MoBiTec GmbH introduces new High Performance Expression Vectors for Bacillus subtilis

Bacillus subtilis Pgrac100 Expression Vectors - Plasmid based expression vectors for highly efficient intracellular production of recombinant proteins in Bacillus subtilis

MoBiTec GmbH, Germany, further expands its unique portfolio of non-E. coli expression vectors. The new Pgrac100 vectors for gene expression in Bacillus subtilis complement the current product line by more efficient tools. Available are vectors with His-tag and Strep-tag for easy purification of proteins generated in the cytoplasm.

Features

Strong promoter with improved regulatory elements
Enhanced amount of expressed recombinant proteins
Inducible protein expression
E. coli / B. subtilis shuttle vectors with different tags (His-tag, Strep-tag)
B. subtilis is considered as a GRAS organism (generally regarded as safe)

B. subtilis as expression host
Bacillus subtilis has been developed as an attractive host because of several reasons:

It is non-pathogenic and is considered as a GRAS organism (generally regarded as safe)
It has no significant bias in codon usage
It is capable of secreting functional extracellular proteins directly into the culture medium
(at present, about 60% of the commercially available enzymes are produced by Bacillus species)
A large body of information concerning transcription, translation, protein folding and secretion mechanisms, genetic manipulation and large-scale fermentation has been acquired.

Also available from us are gene expression systems for Bacillus megatetrium and Lactococcus lactis.

MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include two- & one-hybrid systems for in vivo detection of molecular interactions, genomic libraries, DNA vectors for cloning and expression, kits for expression and purification of recombinant proteins, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products as well as general laboratory equipment. In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.

Arne Schulz, Product Manager
T +49 (0)551 707 22 0
F +49 (0)551 707 22 22
E: info@mobitec.com
W: www.mobitec.com
Lotzestrasse 22a, 37083 Goettingen, Germany

This release was published on openPR.