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TransIT-VirusGEN® Transfection Reagent - Ideal for Recombinant Adeno-associated Virus Production

12-03-2018 03:45 PM CET | Science & Education

Press release from: MoBiTec GmbH

Virus Illustration

Virus Illustration

TransIT-VirusGEN® Transfection Reagent by Mirus, USA, is designed to enhance delivery of packaging and transfer vectors to adherent and suspension HEK 293 cell types to increase recombinant adeno-associated virus (AAV) and lentivirus production.

Adeno-associated virus (AAV) is a nonenveloped, single stranded DNA virus from the Paroviridae family notable for its lack of pathogenicity, low immunogenicity and ability to infect both dividing and quiescent cells. Because AAV is replication-defective in the absence of adeno or helper proteins and is not implicated in any known human diseases, it is widely considered a safe gene delivery vehicle for in vivo and in vitro applications. Accordingly, recombinant AAV has become an invaluable tool for gene therapy and the creation of isogenic human disease models.

Lentivirus is an enveloped, single-stranded RNA virus from the Retroviridae family capable of infecting both dividing and non-dividing cells. Combined with an efficient host-genome integration mechanism and the ability to pseudotype the virus, this capability makes recombinant lentivirus a central gene delivery tool for robust and stable transgene expression in target cells.

The TransIT-VirusGEN® Transfection Reagent enables the generation of both high titer AAV and lentivirus in adherent or suspension HEK 293 cell types. With salient features including: high efficiency DNA delivery, culture format versatility, and streamlined virus generation workflows, TransIT-VirusGEN® is an ideal reagent for scientists utilizing a variety of virus platforms to accelerate their research.

Features

• Reliable – Consistent high virus titer production
• Scalable – Efficient across different formats
• Flexible – Address different virus and cell culture systems

For details see:
https://www.mobitec.com/cms/products/bio/02_genomics/TransIT-VirusGEN-Transfection-Reagent.html

Customers in Gemany are welcome to ask for a one-time free sample of Mirus TransIT-VirusGEN® Transfection Reagent.

About MoBiTec GmbH

MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.

In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.

MoBiTec GmbH, Lotzestr. 22a, 37083 Goettingen,
Germany, info@mobitec.com, www.mobitec.com

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