openPR Logo
Press release

High Quality PEG Raw Materials From Biopharma PEG

Polyethylene glycol (PEG) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), it has wide variety of applications depending on the length of the polymer chain and the molecular weight of the final polymer.

The synthesis of PEG is done by polymerizing ethylene oxide, the main ingredient in antifreeze, using a ring-opening technique, which allows for PEGs of a range of molecular weights and molecular weight distributions to be constructed. This range in weights is what makes it suitable for several uses.

While varying the molecular weight of PEG can have slight effects on its characteristics, mostly on its shape and physical appearance, many characteristics define PEG. It is non-toxic, colorless, inert, odorless, and non-volatile. Also, it is incredibly soluble in water, and organic solvents such as benzene, carbon tetrachloride, and chloroform.

Biopharma PEG's PEG raw materials are suitable for activation into PEG derivatives. Biopharma PEG's PEG raw materials are high quality PEGs with very low polydispersity and low to no diol content. It provides high purity PEG raw materials such as mPEG-OH, NH2-PEG-NH2 and 4-ArmPEG-OH for chemical, biological, medical, industrial and commercial uses.

mPEG-OH is a linear monofunctional PEG acid reagent containing a methoxy (CH3O)-capped polyethylene glycol with one hydroxyl group. It is one of the most common PEG raw materials for further derivatization or functionalization to prepare other reactive functional groups on PEG. mPEG-OH has so far been used for various commercial PEGylated drugs, such as PEG-Interferon and PEG-GCSF. And according to public information, mPEG-OH is one of the PEG raw materials for Pfizer's and Moderna's COVID-19 vaccines.

NH2-PEG-NH2 is a homobibifunctional PEG derivative. It has a linear bifunctional PEG crosslinker with active primary amine or NH2 groups, which can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances. NH2-PEG-NH2 can be dissolved in conventional aqueous solutions and most organic solvents, and can also inhibit the non-specific binding of charged molecules to the modified surface.

4-ArmPEG-OH is a common used maltiarm PEG raw material with hydroxyl groups at each terminal of the four arms connected to one pentaerythritol core. It is suitable for further functionalization into PEG derivatives and for hydrogel formation. The indicated molecular weight of 4-ArmPEG-OH is the sum of the PEG molecular weights of all the arms. 

Biopharma PEG offers a wide range of PEG products from lab to commercial scale in both non-GMP and GMP grades. It provides high purity PEG raw materials for chemical, biological, medical, industrial and commercial uses. Email at and start using a superior product for your next product R&D project.

Biopharma PEG Scientific Inc.
Address: 108 Water Street, Room 4D, Watertown, MA 02472, USA
TEL: 1-857-366-6766
Fax: 617-206-9595

Biopharma PEG Scientific Inc. is a biotechnology-oriented company in Watertown, Massachusetts. We are dedicated to manufacturing and supplying high purity monodispersed and polydispersed polyethylene glycol (PEG) derivatives and PEG raw material, PEGylation services, and custom PEG derivative synthesis to clients worldwide. We continuously expand the capability to provide large-scale manufacture of high purity PEG derivatives with an extensive variety of functional groups, in both non-GMP and GMP grade. These PEG linkers have been widely used in bioconjugation, antibody-drug conjugates (ADCs) therapeutic, click chemistry, 3d bioprinting, drug delivery and diagnostics field, etc. 

This release was published on openPR.

Permanent link to this press release:

Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release High Quality PEG Raw Materials From Biopharma PEG here

News-ID: 2635606 • Views: 480

More Releases from Biopharma PEG Scientific Inc.

Biopharma PEG Supplies Cholesterol (Plant-Derived) Used As Excipients for Lipid Nanoparticles (LNPs)
Biopharma PEG Supplies Cholesterol (Plant-Derived) Used As Excipients for Lipid …
Cholesterol, a derivative of cyclopentane polyhydrophenanthrene, is the main steroid compound in mammals. Most of the traditional cholesterol comes from animal brainstem and lanolin, which is of animal origin and has the risk of carrying animal viruses. Biopharma PEG innovatively uses plant sterols as starting materials to prepare plant-derived cholesterol (CAS NO.: 57-88-5) through biological fermentation and green synthesis, eliminating the generation and carrying of viruses from the source. Cholesterol has
Development Trends And Potential Challenges of PROTACs
Development Trends And Potential Challenges of PROTACs
PROTAC technology has been in development for more than 20 years. PROTAC proof-of-concept studies date back to 2001, when Crews' team tested the possibility of artificially induced intracellular protein degradation with a peptide that was too large in molecular weight and required cells to penetrate the peptide to improve cell permeability. The discovery of the first small molecule PROTAC and the subsequent small molecule E3 ligand, reported in 2008, greatly
ADC Drugs For Breast Cancer Treatment
ADC Drugs For Breast Cancer Treatment
Breast cancer is the malignant tumor with the highest morbidity and mortality among women worldwide. At present, the main therapeutic methods include surgery, chemotherapy, radiotherapy, endocrine therapy and targeted therapy, etc. The development and marketing of new drugs have far-reaching significance in improving the survival of breast cancer patients and changing the pattern of breast cancer treatment. On February 24, 2023, The NMPA approved Enhertu, an injectable drug developed jointly by
History Development of Hydrogels
History Development of Hydrogels
Hydrogels are composed of hydrophilic polymers, whose three-dimensional network structure can not only absorb a large amount of water, but also be used to carry drugs. Hydrogels prepared with suitable materials have the characteristics of high biocompatibility, mechanical and viscoelastic control. Since the term was coined in the late 19th century, hydrogels have been widely used in drug delivery, wound dressing, tissue engineering, and hygiene products. This article mainly introduces

All 5 Releases

More Releases for NH2

Semaglutide VS Liraglutide: Which Is Better For Weight Loss
Among adults with overweight or obesity, once-weekly subcutaneous semaglutide plus counseling for diet and physical activity results in significantly greater weight loss at 68 weeks than once-daily subcutaneous liraglutide, according to a study published in the Jan. 11 issue of the Journal of the American Medical Association. Domenica M. Rubino, M.D., from the Washington Center for Weight Management and Research in Arlington, Virginia, and colleagues compared the efficacy and adverse event
Buy Now Best Spice Oloeoresins : Naturalich
Naturalich : Best Oleoresin in India Your search for the best pure quality of oleoresin is now over. Choose Natuaralich choose Smart. Nurturing the true essence of our name, just as purpose of Ozone is to absorb harmful radiations and serve Earth with safe atmosphere, Ozone Naturals is a business brand committed passionately to serve mankind with natural products, “As Natural as Nature made it to be”. Naturalich offers wide range of
Buy Pure and Natural Spice Oils
Naturalich” a Latin derivative meaning “From Nature”, as name suggest Naturalich deals in natural derived products. Naturalich Essential Oils and derived products have incredible benefits that can be had from using these precious resources and our mission is to provide best quality Natural Essential Oil to every home. Naturalich sources essential oils from all over the world. We work with committed partners to ensure the best growing conditions and produce the
First-class Chelating Agents Covering Full Range Are Available at CD Bioparticle …
Chelating agents are chemical compounds that react with metal ions to form a stable, water-soluble complex. They are also known as chelants, chelators, or sequestering agents. Chelating agents have a ring-like center which forms at least two bonds with the metal ion allowing it to be excreted. Due to the rising demand for cleaning formulations, the market will witness a growing trend in the need for chelating agents, which are
Biochempeg developed a series of PEG compounds used for Semaglutide
Type 2 diabetes is the most common form of diabetes. Semaglutide is an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. It reduces blood sugar via increasing the production of insulin. Biochempeg has developed and can supply some key intermediates of Semaglutide. Semaglutide(trade names: Rybelsus,Ozempic) is a medication for the treatment of type 2 diabetes. It was discovered in 2012, by a team of researchers
Global and China 2-NH2-2-deoxyadenosine Market Size, Shares, Outlook, Strategy, …
The 'Global and Chinese 2-NH2-2-deoxyadenosine Market, 2011-2021 Market Research Report' is a professional and in-depth study on the current state of the global 2-NH2-2-deoxyadenosine industry with a focus on the Chinese market The 'Global and Chinese 2-NH2-2-deoxyadenosine Industry, 2011-2021 Market Research Report' is a professional and in-depth study on the current state of the global 2-NH2-2-deoxyadenosine industry with a focus on the Chinese market. The report provides key statistics on the