openPR Logo
Press release

MoBiTec to Offer Kits for the Isolation of Circulating and Exosome-Associated Genomic DNA

02-09-2018 03:20 PM CET | Science & Education

Press release from: MoBiTec GmbH

Exosomes

Exosomes

MoBiTec's partner company HansaBioMed is the first company that developed kits for the isolation of circulating and Exosome-associated genomic DNA: EXO-DNA and EXO-DNAc

Circulating DNA is emerging as a novel non-invasive tool for disease monitoring. While most of the research has focused on circulating cell-free (cfDNA) or circulating-tumor-cell (CTC)-derived DNA, extracellular vesicle (EVs)-associated DNA (EVDNA) is emerging as a third valuable "liquid biopsy" platform. In fact, genomic single or double-stranded DNA and mitochondrial DNA have been recently detected in extracellular vesicles. In particular, the majority of double-stranded DNA seems to be associated with tumor-derived exosomes where it represents the entire genome of the cancerous tumor from which exosomes were derived. This discovery corroborates the potential of exosomes, which can be easily obtained from a simple blood test.

MoBiTec's partner company HansaBioMed is the first company that developed two kits for the isolation of circulating and Exosome-associated genomic DNA: EXO-DNA and the new EXO-DNAc, which includes a DNA concentrator for concentrating the yield (4 fold concentration) and increasing the purity of the DNA to the levels required for digital PCR (dPCR) analysis and Next Generation Sequencing (NGS).

Applications:

• Discovering mutations by qPCR or digital PCR

• Direct exosome capture and DNA purification from biofluids of cell media without time-consuming purification steps

• Isolation and profiling of genomic EV-associated DNA by DNase treatment

Advantages:

• Highly pure circulating and EVs-associated DNA

• Fast and easy protocol

• Only small volume amounts required

• Suitable for concomitant profiling of cell-free circulating DNA and EV-associated DNA

• The only kit on the market providing Exosome Standards as control

For details please see: http://www.hansabiomed.eu

All HansaBioMed products can be ordered with MoBiTec as of now!

About MoBiTec GmbH

MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.

In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.

MoBiTec GmbH, Lotzestr. 22a
Goettingen, Germany
info@mobitec.com
www.mobitec.com

This release was published on openPR.

Permanent link to this press release:

Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release MoBiTec to Offer Kits for the Isolation of Circulating and Exosome-Associated Genomic DNA here

News-ID: 938500 • Views:

More Releases from MoBiTec GmbH

FerroFarRed - An Ion Indicator for the Specific Detection of Fe2+
FerroFarRed - An Ion Indicator for the Specific Detection of Fe2+
Intracellular Fe2+ can react with hydrogen peroxide, thereby producing the hydroxyl radical, a reactive oxygen species (ROS). Excessive ROS causes oxidative stress, resulting in cancer and neurodegenerative diseases. FerroFarRed (also known as SiRhoNox-1 or ER-SiRhoNox) is a fluorescent probe,manufactured by Goryo Chemical, Japan, distributed in Europe by MoBiTec GmbH, Germany. FerroFarRed specifically detects labile iron (II) ions (Fe2+) and is known to react with Fe2+ only, separately from other metal
TransIT-VirusGEN® Transfection Reagent - Ideal for Recombinant Adeno-associated Virus Production
TransIT-VirusGEN® Transfection Reagent - Ideal for Recombinant Adeno-associated …
TransIT-VirusGEN® Transfection Reagent by Mirus, USA, is designed to enhance delivery of packaging and transfer vectors to adherent and suspension HEK 293 cell types to increase recombinant adeno-associated virus (AAV) and lentivirus production. Adeno-associated virus (AAV) is a nonenveloped, single stranded DNA virus from the Paroviridae family notable for its lack of pathogenicity, low immunogenicity and ability to infect both dividing and quiescent cells. Because AAV is replication-defective in the
Elabscience's Vast Portfolio of Products for Life Science Research Distributed by MoBiTec Germany
Elabscience's Vast Portfolio of Products for Life Science Research Distributed b …
MoBiTec's most recent select partner Elabscience specializes in immunodiagnostic technology for the life science community, offering a complete platform for R&D and manufacture. Elabscience major products cover Proteins, Antibodies, ELlSA Kits, CLIA Kits, Labeling Kits,Biochemical Kits, Cell Lines, and Other Reagents. Elabscience also offers custom services for customers, including Protein Expression and Purification Service, Custom Antibody Service, Custom ELISA Service, Cell Biology Service, Molecular Biology Service, and Whole Research Project Solutions. Every
MoBiTec to Exhibit at Potsdam Days on Bioanalysis 2018, Taking Place in Potsdam, Germany
MoBiTec to Exhibit at Potsdam Days on Bioanalysis 2018, Taking Place in Potsdam, …
The "Potsdam Days on Bioanalysis" provide an excellent platform for researchers, clinicians, and entrepreneurs to discuss diagnostics' hot topics, trends, and recent developments as well as new areas of application and future markets. Often, the implementation of goal-oriented and profitable cooperations is quite a challenge, in particular when it comes to innovative product developments in the fields of diagnostics and analytics. Typically, challenges lie within finding the right cooperation partners, identifying

All 5 Releases


More Releases for DNA

High-Quality Plasmid DNA Fuels Growth in Global DNA Plasmid Manufacturing Market
🌍 Market Overview The DNA Plasmid Manufacturing Market is experiencing robust growth as advancements in cell & gene therapy, DNA vaccines, and genetic engineering continue to expand globally. Plasmid DNA plays a critical role as a raw material in the development of advanced therapies, fueling demand across biopharmaceutical research and production. Key factors driving the market include: Increasing adoption of gene and cell therapies Rising prevalence of chronic and rare genetic disorders Expansion of DNA-based
DNA Synthesis Market Increasing Demand for Synthetic Genes and DNA Sequences
As demonstrated by Precision Business Insights (PBI), the latest report, the global DNA synthesis market was valued at USD 3,702.0 million in 2023 and is expected to reach USD 10,289.5 million by 2029, growing at a CAGR of 18.6% during the forecast period 2024-2030. The key drivers for the growth of the global DNA synthesis market include increasing demand for synthetic genes and DNA sequences, growing applications in the agriculture
Wealth DNA Code Review Legit Price? (Wealth Manifestation DNA Code Audio Frequen …
Wealth DNA Code Wealth DNA Code is a digital program with seven minutes of soundtracks that manifest and listen to daily to activate the "Wealth DNA," which is part of your DNA to help you attract wealth by making money a part of your mentality and making your dreams to come true. https://bit.ly/Visit-The-Official-Website-Here-To-Order-Wealth-DNA-Code Making money, creating assets as well as increasing wealth are the primary objectives that every human being has to
DNA Paternity Testing Market Size [2022-2029] -DNA Diagnostics Center, EasyDNA, …
A recent market research report added to repository of MR Accuracy Reports is an in-depth analysis of global DNA Paternity Testing. On the basis of historic growth analysis and current scenario of DNA Paternity Testing place, the report intends to offer actionable insights on global market growth projections. Authenticated data presented in report is based on findings of extensive primary and secondary research. Insights drawn from data serve as excellent
DNA Paternity Testing Market Trends 2020 | Growth by Top Companies: DNA Diagnost …
The report begins with the overview of the DNA Paternity Testing Market and offers throughout development. It presents a comprehensive analysis of all the regional and major player segments that gives closer insights upon present market conditions and future market opportunities along with drivers, trending segments, consumer behaviour, pricing factors and market performance and estimation. The forecast market information, SWOT analysis, DNA Paternity Testing market scenario, and feasibility study are
DNA Paternity Testing Market Rapidly Growing in Healthcare, Competitor Analysis …
The exclusive research report on the Global DNA Paternity Testing Market 2020 examines the market in detail along with focusing on significant market dynamics for the key players operating in the market. Global DNA Paternity Testing Industry research report offers granulated yet in-depth analysis of revenue share, market segments, revenue estimates and various regions across the globe. Overview of Global DNA Paternity Testing Market: This report studies the Global DNA Paternity Testing