Press release
Single-Use Bioreactors Market to Reach USD 14.9 Billion by 2030
Single-Use Bioreactors
Single-use bioreactors (SUBs) enable flexible, contamination-resistant, and cost-efficient production-making them essential for mAbs, vaccines, recombinant proteins, viral vectors, and personalized cell therapies.
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Key Takeaways
• Market Size 2023: USD 5.4 billion
• Market Size 2030: USD 14.9 billion
• CAGR (2024-2030): 15.4%
• Largest Segment: Wave-induced and stirred-tank bioreactors
• Primary Demand Drivers: Biologics expansion, advanced therapies, and rapid adoption by CDMOs
Market Story
Single-use bioreactors have transformed bioprocessing by overcoming the limitations of stainless-steel systems-offering:
• Fast turnaround with zero cleaning/sterilization
• Lower contamination risk
• High flexibility for multiproduct facilities
• Reduced capital and operating costs
• Ease of scale-out for cell & gene therapies
• Rapid deployment and modularity
They are now indispensable across:
• Monoclonal antibody (mAb) production
• Vaccines & viral vector manufacturing
• Cell & gene therapy (CAR-T, stem cells)
• mRNA and recombinant protein production
• Perfusion & continuous bioprocessing
• Bioprocess development and pilot-scale studies
The surge in personalized and small-batch therapies significantly boosts demand for single-use systems.
Market Segments
By Type of Bioreactor
• Stirred-Tank Single-Use Bioreactors (Largest Segment)
• Wave-Induced Single-Use Bioreactors
• Hybrid Single-Use Bioreactors
• SUB Accessories & Consumables
Stirred-tank SUBs dominate due to familiarity, scalability, and integration with automation.
By Cell Culture Type
• Mammalian Cell Culture (Largest Application)
• Microbial Cell Culture
• Insect Cell Culture
• Plant Cell Culture
• Stem Cell & Primary Cell Culture
Mammalian cell culture dominates biologics and viral vector manufacturing.
By Application
• Monoclonal Antibodies (mAbs) (Largest Application)
• Vaccines & Viral Vector Production
• Cell & Gene Therapy Manufacturing
• Recombinant Proteins & Enzymes
• mRNA-Based Therapeutics
• Bioprocess Development & R&D
Cell and gene therapy production is the fastest-growing area of adoption.
By Capacity
• Up to 50 L
• 50-500 L
• 500-1500 L (Largest Segment)
• Above 1500 L (Emerging Trend)
High-capacity SUBs (1000-2000 L) are increasingly used for commercial-scale biologics.
By End User
• Biopharmaceutical Companies (Largest End User)
• CDMOs (Fastest Growing Segment)
• CROs & Research Institutes
• Cell Therapy Centers
• Vaccine Manufacturers
CDMOs drive major demand due to multi-client flexible manufacturing requirements.
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Recent Industry Developments
• 2024 - Sartorius expanded its BIOSTAT® STR single-use platform with advanced automation features.
• 2023 - Cytiva launched next-gen single-use XcellerexTM stirred-tank bioreactors with improved process control.
• 2023 - Thermo Fisher Scientific upgraded its HyPerformaTM SUB line for intensified and perfusion bioprocessing.
• 2023 - Merck KGaA introduced high-capacity single-use bioreactors enabling scalable mAb and vaccine production.
• 2023 - PBS Biotech expanded its single-use bioreactor solutions for cell therapy manufacturing.
Expert Quote
"Single-use bioreactors offer flexibility, sterility, and scalability-making them the preferred choice for modern biomanufacturing, especially in mAbs, vaccines, and advanced cell therapies."
- Irfan Tamboli, Business Development Executive, Exactitude Consultancy
Key Market Drivers
1. Growth of Biologics & Biosimilars
mAbs, recombinant proteins, and vaccines require efficient, contamination-free manufacturing.
2. Rising Adoption of Cell & Gene Therapies
Single-use platforms are ideal for small-batch, personalized therapies.
3. Operational Efficiency & Cost Reduction
No cleaning, sterilization, or CIP/SIP steps cuts costs and speeds production.
4. Expansion of CDMOs
CDMOs prefer SUBs due to rapid changeovers and multiproduct flexibility.
5. Increasing Use in Continuous Bioprocessing
SUB-enabled perfusion systems support intense, real-time continuous production.
Forecast Outlook (2024-2030)
Key trends shaping the market include:
• SUB integration with automation & AI-based process control
• Expansion of high-volume (1500-4000 L) disposable bioreactors
• Single-use perfusion bioreactors for continuous manufacturing
• Hybrid stainless + single-use facility designs
• Rapid growth in advanced therapy manufacturing
By 2030, single-use bioreactors will dominate early-stage and mid-scale biologics production facilities worldwide, with growing penetration in commercial-scale setups.
Regional Insights
North America
Largest market driven by strong biologics and cell therapy production capabilities.
Europe
High adoption due to advanced CDMOs and rapid biomanufacturing modernization.
Asia-Pacific (Fastest Growing Region)
China, India, South Korea, and Singapore are expanding single-use-based biomanufacturing hubs.
Latin America & Middle East
Growing biologics and vaccine production drives gradual adoption.
Conclusion
The Single-Use Bioreactors Market is positioned for strong growth as global biopharma adopts flexible, scalable, contamination-resistant production systems. With increasing demand for biologics, vaccines, and personalized therapies, single-use bioreactors will continue to play a critical role in next-generation GMP manufacturing.
This report is also available in the following languages : Japanese (使い捨てバイオリアクター市場), Korean (일회용 바이오리액터 시장), Chinese (一次性生物反应器市场), French (Marché des bioréacteurs à usage unique), German (Markt für Einweg-Bioreaktoren), and Italian (Mercato dei bioreattori monouso), etc.
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About Us
Exactitude Consultancy is a market research & consulting services firm which helps its client to address their most pressing strategic and business challenges. Our market research helps clients to address critical business challenges and also helps make optimized business decisions with our fact-based research insights, market intelligence, and accurate data.
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