Press release
Continuous Bioprocessing Market to Reach USD 18.6 Billion by 2030
Continuous Bioprocessing
Continuous bioprocessing enables uninterrupted production, improved efficiency, reduced footprint, lower costs, and superior product consistency compared to traditional batch processing-making it a cornerstone of next-generation biomanufacturing.
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Key Takeaways
• Market Size 2023: USD 6.2 billion
• Market Size 2030: USD 18.6 billion
• CAGR (2024-2030): 16.9%
• Largest Segment: Continuous upstream bioprocessing
• Key Growth Driver: Increasing demand for biologics & advanced therapies requiring consistent, scalable production
Market Story
Continuous bioprocessing transforms biomanufacturing by enabling real-time control, reduced variability, higher yield, and lower operational costs. The model is gaining widespread adoption across:
• Monoclonal antibodies (mAbs)
• Recombinant proteins
• Vaccines
• Viral vectors & gene therapies
• Cell therapies
• mRNA therapeutics
• Enzyme & peptide production
Key benefits driving adoption include:
• Process intensification
• Smaller facility footprint (biomanufacturing 4.0)
• Faster scale-up & flexibility
• Reduced contamination risks
• Greater automation & PAT integration
• Lower cost per gram of biologic produced
Pharma and CDMOs are increasingly transitioning to hybrid (continuous + batch) and fully continuous setups to meet rising global biologics demand.
Market Segments
By Process Type
• Continuous Upstream Bioprocessing (Largest Segment)
- Perfusion bioreactors
- Continuous feeding strategies
- Automated sampling & monitoring
• Continuous Downstream Bioprocessing
- Continuous chromatography
- Continuous filtration & purification
• End-to-End Integrated Continuous Systems (Fastest Growing)
Upstream dominates due to strong adoption of perfusion-based bioreactors for intensified production.
By Product
• Bioreactors & Perfusion Systems (Largest Product Group)
• Chromatography Systems
• Filtration Systems (TFF, UF/DF)
• Media & Buffers
• Sensors, Probes & PAT Tools
• Single-Use Assemblies
• Automation & Control Software
Perfusion-enabled single-use bioreactors are driving significant technological advancements.
By Application
• Monoclonal Antibodies (Largest Application)
• Vaccine Manufacturing
• Recombinant Protein Production
• Gene Therapy & Viral Vectors
• Stem Cell & Regenerative Medicine
• mRNA Production
• Bioprocess Development
The rapid rise of mRNA and viral vector therapies accelerates adoption across clinical and commercial manufacturing.
By End User
• Biopharmaceutical & Biotechnology Companies (Largest End User)
• CDMOs (Fastest Growing)
• Research & Bioprocess Development Institutes
• Cell Therapy Centers
• CROs specializing in bioprocess testing
CDMOs drive adoption due to multi-client production requirements and demand for scalability.
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Recent Industry Developments
• 2024 - Cytiva launched next-generation perfusion bioreactors with enhanced automation & closed-loop control.
• 2023 - Sartorius expanded its continuous chromatography and integrated downstream platforms.
• 2023 - Merck KGaA (MilliporeSigma) introduced advanced PAT-driven solutions for real-time continuous bioprocess monitoring.
• 2023 - Repligen strengthened its TFF systems for continuous purification workflows.
• 2023 - Thermo Fisher Scientific launched automated continuous bioprocessing modules within its single-use ecosystem.
Expert Quote
"Continuous bioprocessing is redefining the future of biologics manufacturing. Real-time control, higher yield, and lower production costs make it one of the fastest-adopted innovations across global biopharma networks."
- Irfan Tamboli, Business Development Executive, Exactitude Consultancy
Key Market Drivers
1. Increasing demand for biologics & gene therapies
Continuous systems ensure consistent quality and faster production cycles.
2. Shift toward process intensification
Perfusion and continuous chromatography deliver higher productivity with smaller footprints.
3. Adoption of single-use technologies
Single-use perfusion bioreactors reduce contamination and maximize flexibility.
4. PAT-driven real-time monitoring
Integrated sensors, analytics, and AI provide dynamic control and higher reproducibility.
5. Lower cost of goods (COGs) in biomanufacturing
Continuous workflows reduce labor, downtime, and resource consumption.
Forecast Outlook (2024-2030)
Key future trends include:
• Fully connected end-to-end continuous manufacturing plants
• AI-based optimization of perfusion culture
• Smart bioreactors with predictive analytics
• Digitally integrated CDMO production ecosystems
• Increased regulatory acceptance of continuous processes
By 2030, continuous bioprocessing will become mainstream across commercial biologics manufacturing, replacing many traditional batch systems.
Regional Insights
North America
Largest market thanks to strong biologics pipelines, advanced CDMOs, and favorable regulatory support.
Europe
Robust adoption driven by high investments in advanced therapies and bioprocessing technologies.
Asia-Pacific (Fastest Growing Region)
China, India, South Korea, and Singapore rapidly expanding biomanufacturing capabilities using continuous systems.
Latin America & Middle East
Growing adoption among vaccine producers and regional biotech centers.
Conclusion
The Continuous Bioprocessing Market is entering a high-growth era as global biopharma embraces real-time, efficient, and highly controlled manufacturing. With rising biologics demand and next-generation therapy expansion, continuous bioprocessing is poised to become the backbone of future GMP manufacturing worldwide.
This report is also available in the following languages : Japanese (連続バイオプロセス市場), Korean (연속 생물공정 시장), Chinese (连续生物加工市场), French (Marché du bioprocédé continu), German (Markt für kontinuierliche Bioprozesse), and Italian (Mercato della bioelaborazione continua), etc.
Request for a sample of this research report at (Use Corporate Mail ID for Quick Response) @ https://exactitudeconsultancy.com/request-sample/73530
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About Us
Exactitude Consultancy is a market research & consulting services firm which helps its client to address their most pressing strategic and business challenges. Our market research helps clients to address critical business challenges and also helps make optimized business decisions with our fact-based research insights, market intelligence, and accurate data.
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https://www.analytica.global/
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https://exactitudeconsultancy.com/
Connect Us:
Irfan Tamboli
PHONE NUMBER +1 (704) 266-3234
EMAIL ADDRESS: sales@exactitudeconsultancy.com
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