Comprehensive HERG Screening Market Forecast 2025-2034: Growth Trends and Strategic Shifts

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HERG Screening Market Size Valuation Forecast: What Will the Market Be Worth by 2025?
The size of the HERG screening market has seen a swift expansion in the past few years. The market is forecasted to increase from $1.62 billion in 2024 to $1.84 billion in 2025, exhibiting a compound annual growth rate (CAGR) of 13.7%. This surge during the historical period is largely due to factors such as an upswing in drug development operations, regulatory mandates, a growing understanding of cardiac health, as well as a rising incidence of cardiac ailments.

HERG Screening Market Size Forecast: What's the Projected Valuation by 2029?
The market size of HERG screening is set to experience a swift expansion in the forthcoming years. It's anticipated to reach a value of "$2.88 billion in 2029" while progressing at a compound annual growth rate (CAGR) of 11.9%. This enlargement in the predicted timespan can be associated with factors such as the broadening scope of personalized medicine, a rise in drug development activities outsourcing, emerging markets and research, and an emphasis on non-cardiac safety examinations. Dominant trends forecasted for this period encompass the progression of in vitro models, the amalgamation of genomic and proteomic data, advances in computational strategies, focus on pediatric drug safety and partnerships for standardization and data sharing.

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What Are the Drivers Transforming the HERG Screening Market?
The increasing count of individuals suffering from cardiac diseases is anticipated to drive the expansion of the HERG screening market. Cardiac disorders, also recognized as cardiovascular diseases, encompass a variety of conditions affecting the heart and the vascular system, which can lead to severe health consequences by hindering the heart's normal functioning. Such disorders stem from unhealthy lifestyle habits, an aging demographic, genetic predispositions, diabetes, and metabolic issues. HERG screening plays a vital role in pinpointing potential drug contenders, warding off harmful cardiac incidents that might trigger severe heart irregularities like torsade de pointes (TdP), and enhancing patient results. For example, in May 2023, a report by the US-based national public health agency, Centers for Disease Control and Prevention, stated that 1 in 20 adults aged 20 and over had cardiovascular diseases, with 695,000 people suffering and 375,476 individuals losing their lives to these diseases. Moreover, a report by the UK-based government division, Office for National Statistics, in March 2022, disclosed that 20,061 individuals succumbed to heart attacks, marking an increment from the preceding year's figures. As a result, the escalating tally of individuals with cardiac diseases is fuelling the expansion of the HERG screening market.

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Which Fast-Growing Trends Are Poised to Disrupt the HERG Screening Market?
Leading firms in the HERG screening market are focusing on the invention of novel advanced solutions, such as GLP-certified HERG screening services, to improve cardiac safety evaluations during the stages of drug development. This service encompasses good laboratory practice-certified screening of the human ether-a-go-go related gene (hERG) through the usual whole-cell patch-clamp method. The execution of the screening adheres to regulation guidelines like ICH S7A and ICH S7B - crucial for safety pharmacology studies during drug development. For example, Metrion Biosciences Ltd., a pharmaceutical company based in the United Kingdom, initiated the GLP-certified hERG screening service in August 2023. The purpose of this service is to boost Metrion's assistance in the development of small-molecule therapeutics and supplement the company's present cardiac safety service range. Furthermore, this service incorporates the standard whole-cell patch-clamp method for identifying possible cardiac risks prior to commencing Phase 1 clinical trials in humans, offers regulatory advice for safety pharmacology studies during drug development, and delivers high-quality biology services to clients for ion channel targets.

Which Segments in the HERG Screening Market Offer the Most Profit Potential?
The herg screening market covered in this report is segmented -

1) By Type: Gene KCNH2, Mutant KCNH2
2) By Ion Channel: Voltage-Gated, Ligand Gated
3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications

Subsegments:
1) By Gene KCNH2: Wild-Type KCNH2, Recombinant KCNH2
2) By Mutant KCNH2: Mutations: Missense Mutations, Nonsense Mutations, Frameshift Mutations

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Which Firms Dominate the HERG Screening Market by Market Share and Revenue in 2025?
Major companies operating in the HERG screening market are Eurofins-Cerep SA., Aviva Biosciences Inc., AstraZeneca Public Limited Company, Merck KGaA, Charles River Laboratories Inc., Abcam Public Limited Company, Molecular Devices LLC, Caliper Life Sciences Inc., Crprotex Limited, ChanTest Corporation, Creative bioarray Inc., Cellular Dynamics International Inc., Nanion Technologies, Essen Bioscience, ABR-Affinity BioReagents Inc., ACEA Biosciences Inc., Metrion biosciences Inc., Aurora Biomed Inc., Aureus Sciences, RedShift BioAnalytics, B'SYS GmbH, Cambridge Bioscience Ltd., Sophion Bioscience Inc., Fluxion Biosciences Inc., ChemAxon Ltd.

Which Regions Offer the Highest Growth Potential in the HERG Screening Market?
North America was the largest region in the HERG screening market in 2024. Asia-Pacific is expected to be the fastest growing region in the forecast period. The regions covered in the HERG screening market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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