Key Trend Reshaping the HERG Screening Market in 2025: Innovative GLP-Certified hERG Screening Solutions for Enhanced Cardiac Safety in Drug Development

Which drivers are expected to have the greatest impact on the over the herg screening market's growth?
The escalating prevalence of cardiac diseases is predicted to fuel the expansion of the HERG screening market in the future. Cardiac disorders, frequently known as cardiovascular diseases, include an array of conditions impacting the heart and blood vessels. These diseases can impede the proper functioning of the heart, leading to severe health issues. Such disorders emerge due to unhealthy lifestyles, an elderly population, genetic predispositions, diabetes, and metabolic syndrome. HERG screening aids in pinpointing potential drug solutions, averting detrimental cardiac incidents which could instigate lethal cardiac arrhythmias, specifically torsade de pointes (TdP), thereby enhancing patient outcomes. For example, as per a report unveiled by the Centers for Disease Control and Prevention in May 2023, 1 in every 20 adults aged 20 or above in the US suffer from cardiovascular diseases. This report found that 695,000 individuals were affected by cardiovascular diseases, with 375,476 deaths. Separately, according to the Office for National Statistics report in March 2022, heart attack deaths in the UK rose to 20,061, an upward trend from the preceding year. Hence, the rapid surge in cardiac disorder patients is boosting the HERG screening market's growth.

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What is the future CAGR of the herg screening market, and how will it impact industry expansion?
The market size for HERG screening has seen a quick expansion in the past years. The market is set to surge from $1.62 billion in 2024 to $1.84 billion in 2025, boasting a compound annual growth rate (CAGR) of 13.9%. Growth during the historic period is linked to an upsurge in drug development endeavors, regulatory demands, growing consciousness about cardiac safety, and an increasing occurrence of heart-related conditions.

The market size of HERG screening is projected to experience a swift expansion in the forthcoming years, reaching $2.9 billion by 2029 with a compound annual growth rate (CAGR) of 12.0%. This anticipated growth throughout the forecast period is linked with the rise of personalized medicine, heightened outsourcing of drug creation processes, the surfacing of new markets and research, along with an emphasis on non-cardiac safety analyses. Key trends predicted for the forecast period encompass the development of sophisticated in vitro models, incorporation of genomic and proteomic information, progress in computational methodologies, focus on child drug safety, as well as partnerships for data interchange and standardization.

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What are the most significant trends transforming the herg screening market today?
Leading firms in the HERG screening market are focusing on introducing new, innovative advanced solutions like GLP-certified HERG screening services to bolster cardiac safety evaluations during drug development procedures. This kind of service pertains to good laboratory practice-certified screening of the human ether-à-go-go related gene (hERG) using the standard whole-cell patch-clamp method, ensuring it aligns with regulatory guidelines such as ICH S7A and ICH S7B that are crucial for safety pharmacology studies during drug development. For example, UK's Metrion Biosciences Ltd unveiled its GLP-certified hERG screening service in August 2023. This service aims to boost Metrion's support for small-molecule therapeutic development and expand the company's existing cardiac safety service range. Besides, this service uses the standard whole-cell patch-clamp technique to identify potential cardiac liabilities before starting Phase 1 clinical trials in humans, provides regulatory guidance for safety pharmacology studies during drug development, and offers clients premium biology services for ion channel targets.

Which key market segments comprise the herg screening market and drive its revenue growth?
The HERG screening market covered in this report is segmented -

1) By Type: Gene KCNH2, Mutant KCNH2
2) By Ion Channel: Voltage-Gated, Ligand Gated
3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications

Subsegmeents:
1) By Gene KCNH2: Wild-Type KCNH2, Recombinant KCNH2
2) By Mutant KCNH2: Mutations: Missense Mutations, Nonsense Mutations, Frameshift Mutations

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What regions are at the forefront of herg screening market expansion?
North America was the largest region in the HERG screening market in 2024. Asia-Pacific is expected to be the fastest growing region in the forecast period. The regions covered in the HERG screening market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

Who are the leading players fueling growth in the herg screening market?
Major companies operating in the HERG screening market are Eurofins-Cerep SA., Aviva Biosciences Inc., AstraZeneca Public Limited Company, Merck KGaA, Charles River Laboratories Inc., Abcam Public Limited Company, Molecular Devices LLC, Caliper Life Sciences Inc., Crprotex Limited, ChanTest Corporation, Creative bioarray Inc., Cellular Dynamics International Inc., Nanion Technologies, Essen Bioscience, ABR-Affinity BioReagents Inc., ACEA Biosciences Inc., Metrion biosciences Inc., Aurora Biomed Inc., Aureus Sciences, RedShift BioAnalytics, B'SYS GmbH, Cambridge Bioscience Ltd., Sophion Bioscience Inc., Fluxion Biosciences Inc., ChemAxon Ltd.

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What Is Covered In The HERG Screening Global Market Report?

•Market Size Forecast: Examine the herg screening market size across key regions, countries, product categories, and applications.
•Segmentation Insights: Identify and classify subsegments within the herg screening market for a structured understanding.
•Key Players Overview: Analyze major players in the herg screening market, including their market value, share, and competitive positioning.
•Growth Trends Exploration: Assess individual growth patterns and future opportunities in the herg screening market.
•Segment Contributions: Evaluate how different segments drive overall growth in the herg screening market.
•Growth Factors: Highlight key drivers and opportunities influencing the expansion of the herg screening market.
•Industry Challenges: Identify potential risks and obstacles affecting the herg screening market.
•Competitive Landscape: Review strategic developments in the herg screening market, including expansions, agreements, and new product launches.

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