Expanding HERG Screening Market Fueled By Increasing Prevalence Of Heart Disorders Driver: A Major Catalyst in the Evolution of the HERG Screening Market in 2025

How Is the HERG Screening Market Projected to Grow, and What Is Its Market Size?
The HERG screening market will grow from $1.62 billion in 2024 to $1.84 billion in 2025, reflecting a CAGR of 13.9%. The growth is attributed to increasing drug development activities, regulatory requirements, rising awareness of cardiac safety, and an increasing incidence of cardiac disorders.

The HERG Screening market is expected to grow to $2.9 billion by 2029 at a CAGR of 12.0%. Expansion in personalized medicine, outsourcing of drug development, and focus on non-cardiac safety assessments contribute to growth. Trends include advanced in vitro models, genomic and proteomic data integration, and pediatric drug safety.

What Are the Key Drivers Behind the Growth of the HERG Screening Market?
The rising prevalence of heart disorders is expected to contribute to the growth of the HERG screening market. Cardiovascular disorders affect the heart and blood vessels, hindering the heart's ability to function and potentially leading to severe health issues. These conditions are often caused by unhealthy lifestyles, aging, genetic factors, diabetes, and metabolic syndrome. HERG screening is crucial for identifying drug candidates, preventing adverse cardiac events, and reducing the risk of potentially fatal arrhythmias like torsade de pointes (TdP). For example, in May 2023, the Centers for Disease Control and Prevention (CDC) reported that 1 in 20 adults aged 20 and above have cardiovascular diseases, with 695,000 people affected and 375,476 fatalities. Furthermore, in March 2022, the Office for National Statistics in the UK reported 20,061 heart attack deaths, marking an increase from the previous year. This rise in heart disorder patients is driving the growth of the HERG screening market.

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Who Are the Major Industry Players Fueling HERG Screening Market Expansion?
Major companies operating in the HERG screening market are Eurofins-Cerep SA., Aviva Biosciences Inc., AstraZeneca Public Limited Company, Merck KGaA, Charles River Laboratories Inc., Abcam Public Limited Company, Molecular Devices LLC, Caliper Life Sciences Inc., Crprotex Limited, ChanTest Corporation, Creative bioarray Inc., Cellular Dynamics International Inc., Nanion Technologies, Essen Bioscience, ABR-Affinity BioReagents Inc., ACEA Biosciences Inc., Metrion biosciences Inc., Aurora Biomed Inc., Aureus Sciences, RedShift BioAnalytics, B'SYS GmbH, Cambridge Bioscience Ltd., Sophion Bioscience Inc., Fluxion Biosciences Inc., ChemAxon Ltd.

Which Key Developments Are Influencing the HERG Screening Market?
Key players in the HERG screening market are focusing on novel, advanced solutions like GLP-certified HERG screening services to enhance cardiac safety evaluations in drug development. This service involves screening the human ether-à-go-go related gene (hERG) with the traditional whole-cell patch-clamp technique, ensuring compliance with regulatory standards like ICH S7A and ICH S7B for safety pharmacology studies. For instance, in August 2023, Metrion Biosciences Ltd., a UK-based pharmaceutical company, launched its GLP-certified hERG screening service. This service is aimed at supporting small-molecule drug development and complements the company's existing cardiac safety portfolio. The service uses the whole-cell patch-clamp technique to assess cardiac risks before Phase 1 clinical trials and provides regulatory guidance for safety pharmacology.

How Is the Segmentation of the HERG Screening Market Defined?
The HERG screening market covered in this report is segmented -

1) By Type: Gene KCNH2, Mutant KCNH2
2) By Ion Channel: Voltage-Gated, Ligand Gated
3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications

Subsegmeents:
1) By Gene KCNH2: Wild-Type KCNH2, Recombinant KCNH2
2) By Mutant KCNH2: Mutations: Missense Mutations, Nonsense Mutations, Frameshift Mutations

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What Is the Leading Region in the HERG Screening Market?
North America was the largest region in the HERG screening market in 2024. Asia-Pacific is expected to be the fastest growing region in the forecast period. The regions covered in the HERG screening market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

What Is Covered In The HERG Screening Global Market Report?

- Market Size Analysis: Analyze the HERG Screening Market size by key regions, countries, product types, and applications.
- Market Segmentation Analysis: Identify various subsegments within the HERG Screening Market for effective categorization.
- Key Player Focus: Focus on key players to define their market value, share, and competitive landscape.
- Growth Trends Analysis: Examine individual growth trends and prospects in the Market.
- Market Contribution: Evaluate contributions of different segments to the overall HERG Screening Market growth.
- Growth Drivers: Detail key factors influencing market growth, including opportunities and drivers.
- Industry Challenges: Analyze challenges and risks affecting the HERG Screening Market.
- Competitive Developments: Analyze competitive developments, such as expansions, agreements, and new product launches in the market.

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