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RNAi Pesticides Market to Reach USD 1,282 Million by 2031 Top 10 Company Globally

08-08-2025 01:57 AM CET | Business, Economy, Finances, Banking & Insurance

Press release from: QY Research

RNAi Pesticides Market to Reach USD 1,282 Million by 2031 Top 10

RNA interference (RNAi) pesticides are cutting-edge biocontrol agents that suppress specific pest genes using double-stranded RNA (dsRNA). They're designed to target only the intended pests such as insects, fungi, and nematodes while sparing beneficial organisms and reducing environmental residues. With rising concerns about chemical resistance, food safety, and ecological impact, RNAi pesticides are becoming integral to modern, sustainable pest management systems.

The global RNAi pesticides market was valued at approximately USD 180 million in 2024, with an estimated 30,2% CAGR, expected to reach USD 1,282 million by 2031. The market is experiencing robust global growth, driven by higher regulatory scrutiny on traditional chemical pesticides, rising pest resistance, and increasing farmer and consumer demand for environmentally sustainable solutions.
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Latest Trends and Technological Developments
In January 2024, GreenLight Biosciences secured EPA registration for its dsRNA-based spray, Calantha, targeting the Colorado potato beetle, marking a pivotal commercial milestone. Rising concerns about insect resistance are pushing demand for precise, sustainable technologies such as RNAi and peptide-based pesticides. Notably, Asia-Pacific RNAi pesticide markets, valued at just USD 5.49 million in 2024, are projected to quadruple to over USD 22 million by 2031, propelled by innovative delivery systems and supportive regional policies.
Asia-Pacific is poised to become a growth powerhouse in RNAi adoption, supported by strong ag-tech investments, precision agriculture initiatives, and policy incentives like Japan's MAFF subsidies and India's organic farming schemes (PMAY). The regions vast agricultural sectors create a compelling use case for RNAi's sustainability and efficacy.

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RNAi Pesticides by Type:
Topical RNAi Pesticides

Seed Embedded RNAi

Transgenic RNAi

Others

RNAi Pesticides by Application:
Agricultutral Application

Non Agricultural Application

Others

Global Top 10 Key Companies in the RNAi Pesticides Market
GreenLight Biosciences

Bayer CropScience

Corteva Agriscience

Syngenta Group

Bayer AG

RNAissance AG

Enko Chem Inc.

Elo Life Systems

Futureco Bioscience

Xiaomo Biotech Limited

Regional Insights
While RNAi pesticide consumption in Southeast Asia remains nascent, it is rapidly advancing. Growing adoption of eco-agricultural models and pilot outreach begun in countries like Thailand and Vietnam suggest promising potential. As formulation costs fall and awareness rises, Southeast Asia could reach an estimated USD 20-30 million market valuation by 2030, bolstered further by regional biomass availability and IPM integration.
RNAi Pesticides by Region:
North America
Europe
China
Japan
India
South East Asia

Key roadblocks include high dsRNA production costs, intricate regulatory approval pathways, and limited familiarity among farmers. Cold-chain logistics for dsRNA sprays and limited perception of biotechnology in agriculture also hamper distribution and acceptance. Moreover, robust packaging and controlled application methods are still evolving to improve field effectiveness and uptake.
Companies should strengthen collaboration with established agrochemical corporations to expedite commercialization and cost scaling. Investing in advanced dsRNA synthesis, nanocarrier delivery systems, and field stability enhancements will improve product uptake. Tailoring species-specific solutions for regional pests and integrating RNAi into IPM frameworks offers strong differentiation in adoption strategies towards both large agribusinesses and small-scale farmers.
Product Models
RNA interference (RNAi) pesticides represent a cutting-edge approach in crop protection, leveraging gene-silencing mechanisms to target specific pests with precision. These biopesticides work by disrupting vital gene expression in target organisms, reducing damage without harming non-target species.
Topical RNAi Pesticides, which are sprayed directly onto plants. Notable products include:
Bayer BioDirect dsRNA Spray: A foliar-applied RNAi targeting Colorado potato beetle, disrupting vital gene functions upon ingestion.
GreenLight Biosciences Calantha RNAi Spray: Designed for controlling corn rootworm, applied as a non-GMO foliar treatment.
Agrospheres RNAi Biopesticide: Encapsulated dsRNA targeting lepidopteran pests, designed for vegetable and cotton crops.
RNAissance Ag Foliar dsRNA: Targets soybean aphid and corn earworm with biodegradable spray formulations.
Bioceres Crop Solutions RNAi Foliar Control: Non-GMO bioformulation aimed at leaf miner suppression in high-value horticulture.
Seed-Embedded RNAi which incorporate RNAi molecules into coated seeds for systemic protection. Examples include:
Monsanto MON87411 Maize: Contains seed-applied RNAi to combat corn rootworm via gene silencing.
GreenLight SeedGuard RNAi Coated Seeds: Targeting seed corn maggot and cutworm with RNAi payload inside the seed coating.
RNAitech SmartSeed Platform: Microencapsulated dsRNA infused in seed coating to suppress pest larvae during early crop stages.
Renaissance BioAg RNAi Seed Protection: Protects seedlings against wireworms and cutworms using polymer-bound RNAi formulations applied during seed processing.
CropOS RNAi Enhanced Oilseed Rape Seeds: Developed for European markets, these seed-treated varieties target cabbage stem flea beetle through RNAi delivery.
Transgenic RNAi where plants are genetically engineered to express RNAi molecules internally. Products examples include:
MON87411 Corn (Monsanto/Bayer): Genetically engineered to express dsRNA targeting western corn rootworm genes internally.
SmartStax® PRO with RNAi (Corteva/Bayer): Combines Bt proteins with transgenic RNAi for multi-mode rootworm resistance.
DuPont Pioneer RNAi Soybean: Experimental transgenic line expressing RNAi to deter soybean cyst nematode.
Syngenta RNAi-Expressing Cotton (Viptera RNAi): Targets lepidopteran pests through plant-encoded RNA expression.
Inari Transgenic RNAi Canola: Enhances resistance to flea beetles using RNA silencing expressed in leaf and stem tissue.

The RNAi pesticide market is emerging as a high-growth segment in sustainable agriculture. Valued at approximately USD 180,2 M in 2024 and with potential to grow at close to 30,2% CAGR, RNAi solutions are gaining traction particularly in North America and Asia-Pacific. Despite high costs and regulatory complexity, successful deployments like Calantha and regional policy support forecast a promising future. Strategic scaling, partnerships, and technological advancement, especially across farming-intensive Asia and Southeast Asia, can catalyze mainstream adoption.

Investor Analysis
RNAi pesticides represent a transformative, high-growth sector (USD 180,2 M in 2024, 30,2% CAGR) offering targeted, environmentally friendly pest control alternatives to traditional chemical pesticides.
Investors may benefit by partnering with pioneering startups like GreenLight, investing in dsRNA manufacturing infrastructure, or collaborating with large agrochemical companies developing regulatory pathways.
RNAi aligns with global sustainability mandates, evolving regulatory environments, and consumer demand shift. With Asia-Pacific and Southeast Asia moving toward green agricultural solutions, early capital positioning offers both strategic differentiation and significant upside.
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5 Reasons to Buy This Report
Detailed market sizing and actionable forecasts for RNAi pesticides through 2031.
Regional insights spotlighting Asia-Pacific's rapid expansion and emerging Southeast Asia markets.
Technology overview covering sprays, RNA delivery systems, and IP partnerships.
Competition mapping of major agrochemical and biotech players.
Strategy-driven roadmap for commercialization, regulatory navigation, and farmer engagement.
5 Key Questions Answered
What was the global market size and expected CAGR for RNAi pesticides from 20242031?
How do key regions like Asia-Pacific and Southeast Asia compare in adoption and market share?
What recent commercialization milestones and technology breakthroughs have occurred?
What are the main barriers to adoption and how can they be addressed?
Who are the leading players and what strategies are they adopting for RNAi product rollout?
Chapter Outline
Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by region, product type, application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: key insights, key emerging trends, etc.
Chapter 3: Manufacturers competitive analysis, detailed analysis of the product manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 4: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 5 & 6: Sales, revenue of the product in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 7: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 8: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 9: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 10: The main points and conclusions of the report.

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