Press release
Pharmaceutical-Grade Polyethylene Glycol (PEG) Market Trends, Forecasts & Key Players
The global pharmaceutical grade polyethylene glycol (PEG) market was valued at USD 3.49 billion in 2024 and is projected to reach USD 6.64 billion by 2034, growing at a CAGR of 6.6% from 2025 to 2034. This growth is fueled by increasing pharmaceutical formulations that require PEG as a binder, solubilizer, or excipient.PEG's hydrophilic nature, safety profile, and versatility in both solid and liquid formulations have made it a key ingredient across oral, topical, ophthalmic, and injectable medications. PEG is also extensively used in PEGylation, a process that improves the pharmacokinetics of biologics and proteins.
Download Full PDF Sample Copy of Market Report @ https://exactitudeconsultancy.com/request-sample/67090
Key Market Drivers
a. Biologics and PEGylated Drugs
The rising demand for biologic drugs, including antibodies and peptides, has significantly increased the use of PEG in PEGylation processes, which extend drug half-life and reduce immunogenicity.
b. Increased Demand for Topical and Ophthalmic Formulations
PEG is widely used in eye drops, creams, gels, and topical anesthetics due to its non-toxic, non-irritating, and hydrating characteristics.
c. Expanding Geriatric Population
PEG-based laxatives and drug formulations are commonly used for elderly patients, fueling demand in both OTC and prescription medication markets.
d. Oral and Controlled-Release Drug Delivery Systems
The demand for controlled-release oral drugs is increasing, and PEG plays a central role in film coatings and matrix formulations that manage drug release.
Key Restraints and Challenges
a. Raw Material Price Fluctuations
PEG is derived from ethylene oxide, a petrochemical product that faces volatility in pricing and availability, especially in energy-crisis scenarios.
b. Environmental Concerns
There are concerns around PEG biodegradability and its long-term environmental footprint, especially in high-volume topical or dermal formulations.
c. Alternatives in Specialty Pharma
Some biotech players are exploring non-PEGylated delivery platforms, particularly for advanced targeted drug delivery systems.
Get Your Exclusive Offer with up to 10% Discount : https://exactitudeconsultancy.com/checkout/?currency=USD&type=single_user_license&report_id=67090
Opportunities and Trends
a. PEGylated Biopharmaceutical Pipeline
Several PEGylated monoclonal antibodies and protein drugs are in clinical trials, offering long-term opportunities for pharmaceutical-grade PEG manufacturers.
b. High Purity Grades for Injectables
The demand for ultra-high-purity PEG grades suitable for parenteral formulations and gene therapy delivery systems is rising.
c. PEG in Nanomedicine and Drug Carriers
PEG is a key component in lipid nanoparticles (LNPs) and nanocarriers used in mRNA-based therapeutics and vaccines.
d. Rising Role in Oncology and Rheumatology
PEG is used in oncology drug solubilization, injectable anti-inflammatory formulations, and cancer adjuvants, particularly in combination therapies.
Market Segmentation
By Molecular Weight
• PEG 200-400
• PEG 400-6000
• PEG 6000-10000
• Above 10000
PEG 400-6000 is the dominant segment due to its widespread use in oral, topical, and parenteral pharmaceutical applications.
By Application
• Laxatives and Osmotic Agents
• Topical Ointments and Eye Drops
• Tablet Coatings and Binders
• Injectable PEGylated Drugs
• Excipient for Controlled Release Systems
Laxatives and topical formulations hold the largest market share, while PEGylated injectables are witnessing the fastest growth.
By End-Use
• Pharmaceutical Manufacturing Companies
• Biotechnology & Biologics Firms
• Contract Manufacturing Organizations (CMOs)
• Research Institutions and Labs
Regional Insights
North America
North America held 38% of the global pharmaceutical PEG market in 2023, attributed to:
• High consumption of oral and injectable drugs
• Presence of leading PEG suppliers and CDMOs
• Accelerated demand for PEGylated biologics and mRNA-based therapies
• FDA approvals for PEG-based excipients and formulations
Europe
• Robust pharmaceutical manufacturing hubs in Germany, Switzerland, and the UK
• Strict quality standards fueling demand for high-purity PEG grades
• Significant presence of biotech firms using PEG in clinical-stage drug development
Asia Pacific
• Fastest-growing region with increasing drug manufacturing capacity in India, China, and South Korea
• Government incentives for bulk drug parks and excipient production
• Rising demand for generic formulations and biosimilars using PEG
Latin America
• Growing consumption of over-the-counter (OTC) PEG-based laxatives and ointments
• Expansion of pharmaceutical packaging and formulation sectors in Brazil and Mexico
Middle East & Africa
• Increasing investment in local pharmaceutical production
• Demand for low-cost oral and topical treatments containing PEG
• Growing distribution of PEG-based syrups and generics through government schemes
Explore Full Report here: https://exactitudeconsultancy.com/reports/67090/pharmaceuropetical-grade-polyethylene-glycol-peg-market
Competitive Landscape
The pharmaceutical-grade PEG market is moderately consolidated, with global players emphasizing molecular weight precision, compliance certifications, and GMP production capabilities.
Key Players
• Dow Chemical Company - A leading PEG supplier offering USP-compliant and GMP-grade polyethylene glycols for oral and topical formulations.
• INEOS - Produces pharmaceutical PEGs across multiple molecular weights, with wide adoption in EU and U.S. pharma markets.
• Merck KGaA - Offers high-purity PEGs and PEG derivatives for injectable biologics and drug delivery systems.
• BASF SE - Focused on multi-functional PEG-based excipients under its Kolliphor® and Lutrol® brands.
• Lotte Chemical - Supplies PEG for drug solubilization and liquid pharmaceutical systems, primarily in Asia.
• Liaoning Oxiranchem - A key Chinese supplier of PEG 400, PEG 6000 for pharmaceutical and cosmetic use.
• NOF Corporation - Pioneer in PEGylation technologies and bio-conjugation, supplying to global biologic developers.
• Croda International - Specializes in custom PEG derivatives for mRNA vaccine delivery and ophthalmic drugs.
• SABIC - Focused on pharma-grade polymers, including PEG used in coatings and capsule formulations.
• Clariant - Developing sustainable PEG-based excipients and collaborating with CDMOs for injectable platforms.
Recent Developments (2025)
1. January 2025 - Merck KGaA
Launched a new high-purity PEG 3350 line for use in oral rehydration therapy and pediatric electrolyte formulations in the U.S. and EU.
2. February 2025 - BASF SE
Expanded its Kolliphor® PEG excipient line with thermo-sensitive PEG blends for sustained topical release in dermatological drugs.
3. March 2025 - NOF Corporation
Signed a licensing agreement with a U.S. biotech firm to co-develop PEGylated siRNA delivery platforms, enabling next-gen RNA therapeutics.
4. April 2025 - Dow Chemical Company
Opened a new PEG production plant in Texas, increasing U.S.-based capacity for pharmaceutical and personal care applications.
5. May 2025 - Croda International
Partnered with an mRNA vaccine manufacturer in India to supply PEG-lipid conjugates for LNP systems, targeting tropical disease vaccines.
Events and Implications
• PEGylation Boom: Biopharma innovation is accelerating demand for injectable PEGs with narrow molecular weight distribution.
• Excipient Compliance: Global regulatory bodies are pushing for excipients with traceability, USP/Ph. Eur. compliance, and GMP validation.
• RNA & Nanomedicine: PEG is key to lipid nanoparticle (LNP) systems used in mRNA, siRNA, and gene editing platforms.
• Asia's Rise: Asian manufacturers are scaling PEG production for both domestic use and Western contract manufacturing partnerships.
• Sustainable PEGs: Companies are investing in biobased ethylene oxide and environmentally friendly PEG derivatives to meet ESG goals.
Conclusion
The pharmaceutical grade polyethylene glycol (PEG) market is positioned for steady and strategic growth over the next decade. As drug formulations become more sophisticated, the demand for excipients that enhance solubility, stability, and bioavailability will only grow stronger-cementing PEG's role as a high-impact, multifunctional polymer.
Innovations in PEGylation, RNA delivery, topical systems, and pediatric drug formulations will continue to shape the market. Manufacturers that invest in purity standards, regulatory certifications, and global scalability will lead in supplying this essential pharmaceutical building block through 2034.
This report is also available in the following languages : Japanese (医薬品グレードのポリエチレングリコール(PEG)市場), Korean (제약용 폴리에틸렌 글리콜(PEG) 시장), Chinese (医药级聚乙二醇(PEG)市场), French (Marché du polyéthylène glycol (PEG) de qualité pharmaceutique), German (Markt für Polyethylenglykol (PEG) in pharmazeutischer Qualität), and Italian (Mercato del polietilenglicole (PEG) di grado farmaceutico), etc.
Request for a sample of this research report at (Use Corporate Mail ID for Quick Response) @ https://exactitudeconsultancy.com/reports/67090/pharmaceuropetical-grade-polyethylene-glycol-peg-market#request-a-sample
Our More Reports:
automotive glass with HUD integration Market
https://exactitudeconsultancy.com/reports/66945/automotive-glass-with-hud-integration-market
Thermal Insulation Materials Market
https://exactitudeconsultancy.com/reports/66947/thermal-insulation-materials-market
Recycled Materials Market
https://exactitudeconsultancy.com/reports/66949/recycled-materials-market
About Us
Exactitude Consultancy is a market research & consulting services firm which helps its client to address their most pressing strategic and business challenges. Our market research helps clients to address critical business challenges and also helps make optimized business decisions with our fact-based research insights, market intelligence, and accurate data.
https://bulletin.exactitudeconsultancy.com/
https://www.thehealthanalytics.com/
https://www.analytica.global/
https://www.marketintelligencedata.com/
https://www.marketinsightsreports.com/
https://exactitudeconsultancy.com/
Connect Us:
Irfan Tamboli
PHONE NUMBER +1 (704) 266-3234
EMAIL ADDRESS: sales@exactitudeconsultancy.com
This release was published on openPR.
Permanent link to this press release:
Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.
You can edit or delete your press release Pharmaceutical-Grade Polyethylene Glycol (PEG) Market Trends, Forecasts & Key Players here
News-ID: 4116421 • Views: …
More Releases from Exactitude Consultancy

Viral Vector Manufacturing Market to Surge to USD 43.04 Billion by 2034, Growing …
Introduction
The healthcare industry is entering a transformative era where precision therapies are reshaping how we treat diseases. Among the most groundbreaking innovations, viral vectors have emerged as critical enablers of gene and cell therapies. These engineered viruses act as vehicles to deliver therapeutic genetic material directly into patients' cells, making them indispensable for modern medicine. From treating rare genetic disorders to powering revolutionary CAR-T cell therapies in oncology, viral vectors…

Veterinary Vaccines Market to Reach USD 20.65 Billion by 2034, Growing at 6.4% C …
Introduction
Animal health is a cornerstone of global food security, sustainable agriculture, and public health. With rising concerns over zoonotic diseases, antimicrobial resistance, and livestock productivity, the role of veterinary vaccines has never been more critical. These vaccines not only protect animal populations from infectious diseases but also indirectly safeguard humans by preventing disease transmission from animals.
In 2024, the global Veterinary Vaccines Market is valued at USD 11.25 billion and is…

Intravenous Immunoglobulin (IVIG) Market to Reach USD 27.1 Billion by 2034, Grow …
Introduction
In recent years, the healthcare industry has seen significant progress in therapies targeting immune system disorders and rare diseases. At the forefront of these therapies is Intravenous Immunoglobulin (IVIG) - a plasma-derived product containing antibodies that play a crucial role in strengthening or modulating immune response. IVIG is widely used in treating primary and secondary immunodeficiency disorders, autoimmune diseases, neurological disorders, and hematological conditions.
With the rising prevalence of chronic illnesses,…

Lipid Nanoparticle Manufacturing Market to Reach USD 2.48 Billion by 2034, Growi …
Introduction
The pharmaceutical and biotechnology industries are undergoing a paradigm shift driven by the success of mRNA vaccines and the growing promise of gene therapies. At the heart of these breakthroughs are lipid nanoparticles (LNPs) - tiny, lipid-based carriers that safely deliver nucleic acids like mRNA, siRNA, and DNA into target cells. LNPs are now recognized as the gold standard for nucleic acid delivery, fueling advancements in infectious disease prevention, oncology,…
More Releases for PEG
Biopharma PEG Delivers Innovative PEG Solutions for Enhanced Drug Efficacy
Watertown, MA - October 24, 2024 - Biopharma PEG is excited to announce its extensive offerings of polyethylene glycol (PEG) products, including monofunctional, homobifunctional, heterobifunctional, and multi-arm PEGs, tailored for PEGylation in biopharmaceutical applications. With over 40 PEGylated drugs approved globally, the role of PEGylation in drug development is more critical than ever.
PEGylation provides numerous advantages, such as improved solubility, enhanced stability, and increased circulation time in the bloodstream. By…
Biopharma PEG Expands Multi-Arm PEG Product Line
Biopharma PEG, a leader in PEG derivatives, is excited to announce the expansion of its high-purity Multi-Arm PEG linker product line, catering to the evolving needs of the medical and bioorganic fields. These advanced PEG linkers are available in various functional groups and molecular weights ranging from 1k to 40k, offering unmatched versatility and performance for research and development in cutting-edge medical applications.
"Biopharma PEG is committed to delivering high-purity multi-arm…
Biopharma PEG Supplies PEG Products Used For Infectious Disease Vaccines
As of January 1, 2023, global vaccine development includes a total of 966 vaccine candidates, of which 23% (220) are traditional inactivated or attenuated vaccines. Advances in molecular technology have facilitated the development of other platforms, such as recombinant protein vaccines, nucleic acid vaccines, and viral vector vaccines, which have further diversified global vaccine development.
Recombinant protein vaccines accounted for the largest proportion of all pipeline in development, 22% (215), due…
Biopharma PEG Supplies PEG Products For Click Chemistry Reactions
What is "click chemistry"? "Click Chemistry", this is a literary name given to this kind of reaction by the Nobel Prize winner K.Burry Sharless, when the cards are put together, "click" (click). Simply put, it is to add two structures to two molecules respectively, and these two structures can be specifically combined to synthesize the required chemical molecules. One of the most famous click-chemistry reactions is the Cu-catalyzed azide-alkyne cycloaddition…
Biopharma PEG Develops PEG Linkers for Antibody Drug Conjugates
Antibody-drug conjugate (ADC) is one of the fastest growing fields in tumor therapy, which consists of monoclonal antibody (Antibody), linker (Linker) and active drug (Payload). So far, there are only 15 drugs on the market in the world. However, with the development of some perfect antibody modification techniques, advanced site-specific coupling techniques and powerful small-molecule toxins, ADC drug research has mushroomed and a large number of ADC drugs are in…
Biopharma PEG Provides Multi-arm PEG Derivatives Crosslinked Into Hydrogels
Polyethylene (ethylene glycol) is a hydrophilic polymer that can have a very high water content when cross-linked into a network. Polyethylene glycol (PEG) is a suitable material for biological applications because it does not normally elicit an immune response. Since the 1970s, PEG has been used to modify therapeutic proteins and peptides in order to increase their solubility, reduce their toxicity, and prolong their cyclic half-lives. In the late 1970s,…