Press release
The Future of Refractory Multiple Myeloma Therapy: 75+ Companies Advancing the Clinical Pipeline | Rapa Therapeutics, Novartis, AbbVie, MiNK Therapeutics, AbbVie, Amgen
Refractory Multiple Myeloma Pipeline
DelveInsight's 'Refractory Multiple Myeloma Pipeline Insight 2024' report provides comprehensive global coverage of pipeline Refractory Multiple Myeloma therapies in various stages of clinical development. Major pharmaceutical companies are working to advance the pipeline space and future growth potential of the Refractory Multiple Myeloma pipeline domain.
For Refractory Multiple Myeloma emerging drugs, the Refractory Multiple Myeloma pipeline analysis report provides a 360° view of the therapeutics landscape by development point, product type, route of administration, molecule type, and MOA. The pipeline research covers business opportunities, challenges, future partnerships, strong competitors, and growth strategies.
Key Takeaways from the Refractory Multiple Myeloma Pipeline Report
• DelveInsight's Refractory Multiple Myeloma Pipeline analysis depicts a robust space with 75+ active players working to develop 80+ pipeline drugs for Refractory Multiple Myeloma treatment.
• The leading Refractory Multiple Myeloma companies include MorphoSys, Janssen Research & Development, LLC, Rapa Therapeutics, Novartis, AbbVie, MiNK Therapeutics, AbbVie, Amgen, Gracell Biopharmaceuticals, Inc., Zhejiang ACEA Pharmaceutical Co. Ltd., Allogene Therapeutics, Beijing InnoCare Pharma Tech Co., Ltd., Takeda, Novartis Pharmaceuticals, and others are evaluating their lead assets to improve the Refractory Multiple Myeloma treatment landscape.
• Key Refractory Multiple Myeloma pipeline therapies in various stages of development include Felzartamab, Talquetamab, RAPA-201, PHE885, ABBV 453, AGENT 797, Venetoclax, Dexamethasone, GC012F, STI-6129, ABT-199, ALLO-605, ICP-490, TAK-981, AUY922, and others.
• In February 2025, Opna Bio announced that its oral small molecule inhibitor, OPN-6602, received FDA Orphan Drug designation for multiple myeloma. OPN-6602 targets E1A-binding protein (EP300) and CREB-binding protein (CBP).
• In December 2024, Bristol Myers Squibb and 2seventy bio, Inc. announced that the U.S. Food and Drug Administration (FDA) approved Abecma® (idecabtagene vicleucel; ide-cel) for the treatment of adult patients with relapsed or refractory multiple myeloma.
• In Nov 2024, Nanjing Leads Biolabs Co., Ltd. announced that LBL-034, a humanized bispecific T-cell engaging antibody targeting GPRC5D and CD3 for multiple myeloma, has received Orphan Drug Designation (ODD) from the FDA.
• In Sept 2024, Sanofi's SARCLISA (isatuximab) gotapproved by the FDA as the first anti-CD38 therapy in combination with standard-of-care treatment for adult patients with newly diagnosed multiple myeloma who are not eligible for autologous stem cell transplant.
Request a sample and discover the recent breakthroughs happening in the Refractory Multiple Myeloma pipeline landscape @ https://www.delveinsight.com/report-store/refractory-multiple-myeloma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=jpr
Refractory Multiple Myeloma Overview
Multiple myeloma is a type of cancer that originates in plasma cells, a type of white blood cell. Although it is considered rare, accounting for less than 2% of cancers, it is the most common form of plasma cell tumor, as stated by the CDC.
Multiple myeloma is classified as refractory when it does not respond to treatment or stops responding during treatment. In patients with refractory multiple myeloma, symptoms that were initially present before treatment may return, or new symptoms may develop. These symptoms are typically the same as those of multiple myeloma and may either persist or recur after treatment.
The most common symptom of multiple myeloma, including refractory multiple myeloma, is bone pain. This occurs because abnormal plasma cells multiply in the bone marrow, the soft tissue inside bones responsible for producing new blood cells.
Experts are still uncertain about the exact cause of multiple myeloma. However, it is believed that gene changes may play a role in making the cancer more resistant to treatment, which could explain why some cases of multiple myeloma become refractory.
Find out more about Refractory Multiple Myeloma medication @ https://www.delveinsight.com/report-store/refractory-multiple-myeloma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=jpr
Refractory Multiple Myeloma Treatment Analysis: Drug Profile
Felzartamab: MorphoSys
Felzartamab is an investigational human monoclonal antibody developed using MorphoSys' HuCAL® antibody technology. The antibody targets against CD38 present on the surface of multiple myeloma cells. The drug candidate uses antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP) for tumor cell killing. Currently it is in Phase III stage of clinical trial evaluation to treat Refractory Multiple Myeloma.
RAPA-201: Rapa Therapeutics
RAPA-201 It is a type of autologous cell therapy. The drug candidate is gene transference, T lymphocyte replacements and work on the same mechanism of action. Currently the drug is being evaluated in Phase II for the treatment of Refractory Multiple Myeloma.
PHE885: Novartis
PHE885 is an autologous, fully human, BCMA-directed CAR T-cell therapy being developed by Novartis for the treatment of refractory multiple myeloma. It is administered through intravenous route. The therapeutic candidate consists of autologous T cells that are genetically modified to express chimeric antigen receptor that targets BCMA (B-cell maturation antigen). Currently it is in Phase II stage of clinical trials.
Key Refractory Multiple Myeloma Therapies and Companies
• Felzartamab : MorphoSys
• Talquetamab : Janssen Research & Development, LLC
• RAPA-201 : Rapa Therapeutics
• PHE885 : Novartis Pharmaceuticals
• ABBV 453 : AbbVie
• AGENT 797 : MiNK Therapeutics
• Venetoclax : AbbVie and Roche
• GC012F : Gracell Biopharmaceuticals, Inc.
• STI-6129 : Sorrento Therapeutics
• ABT-199 : AbbVie
• ALLO-605 : Allogene Therapeutics
• ICP-490 : InnoCare
• TAK-981 : Takeda
• AUY922 : Vernalis
Learn more about the novel and emerging Refractory Multiple Myeloma pipeline therapies @ https://www.delveinsight.com/report-store/refractory-multiple-myeloma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=jpr
Refractory Multiple Myeloma Therapeutics Assessment
By Product Type
• Mono
• Combination
• Mono/Combination.
By Stage
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
By Route of Administration
• Oral
• Parenteral
• Intravenous
• Subcutaneous
• Topical
By Molecule Type
• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy
Scope of the Refractory Multiple Myeloma Pipeline Report
• Coverage: Global
• Key Refractory Multiple Myeloma Companies: MorphoSys, Janssen Research & Development, LLC, Rapa Therapeutics, Novartis, AbbVie, MiNK Therapeutics, AbbVie, Amgen, Gracell Biopharmaceuticals, Inc., Zhejiang ACEA Pharmaceutical Co. Ltd., Allogene Therapeutics, Beijing InnoCare Pharma Tech Co., Ltd., Takeda, Novartis Pharmaceuticals, and others.
• Key Refractory Multiple Myeloma Pipeline Therapies: Felzartamab, Talquetamab, RAPA-201, PHE885, ABBV 453, AGENT 797, Venetoclax, Dexamethasone, GC012F, STI-6129, ABT-199, ALLO-605, ICP-490, TAK-981, AUY922, and others.
Dive deep into rich insights for drugs used for Refractory Multiple Myeloma treatment; visit @ https://www.delveinsight.com/report-store/refractory-multiple-myeloma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=jpr
Table of Contents
1. Introduction
2. Executive Summary
3. Refractory Multiple Myeloma Pipeline: Overview
4. Analytical Perspective In-depth Commercial Assessment
5. Refractory Multiple Myeloma Pipeline Therapeutics
6. Refractory Multiple Myeloma Pipeline: Late-Stage Products (Phase III)
7. Refractory Multiple Myeloma Pipeline: Late-Stage Products (Phase III)
8. Refractory Multiple Myeloma Pipeline: Mid-Stage Products (Phase II)
9. Refractory Multiple Myeloma Pipeline: Early Stage Products (Phase I)
10. Therapeutic Assessment
11. Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Key Companies
14. Key Products
15. Unmet Needs
16. Market Drivers and Barriers
17. Future Perspectives and Conclusion
18. Analyst Views
19. Appendix
Contact Us:
Jatin Vimal
jvimal@delveinsight.com
+14699457679
Healthcare Consulting
https://www.delveinsight.com/consulting-services
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.
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