Press release
Pigment Epithelial Detachment Market Outlook: Aging Population, AI-Driven Diagnosis, and Novel Therapies to Drive Growth, finds DelveInsight | Sumitomo Pharma, Healios, Eyestem Research, Luxa Biotechnology, Regenerative Patch Technologies, Lineage Cell Th
Pigment Epithelial Detachment Market insights
DelveInsight's report, "Pigment Epithelial Detachment - Market Insight, Epidemiology and Market Forecast", provides a comprehensive assessment of retinal pigment epithelium market dynamics, disease epidemiology, and treatment advancements across the 7MM. The report forecasts that the retinal pigment epithelium market size in these regions, which include the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan, is expected to increase significantly in the coming years. This growth will be largely due to an aging population, industry collaborations, and advancements in technologies such as AI-driven diagnostics, telehealth, and therapeutic innovations.
The US currently holds the largest retinal pigment epithelium market share, a trend anticipated to continue due to ongoing innovations in anti-VEGF therapies and advancements in the treatment pipeline. Moreover, Japan's growth rate could surpass others, owing to its aging population and a higher prevalence of PCV-related PED.
Download the Pigment Epithelial Detachment Market report to understand which factors are driving the retinal pigment epithelium therapeutic market @ https://www.delveinsight.com/sample-request/pigment-epithelial-detachment-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=xpr
The epidemiological data presented in the report indicate key trends in incidence, demographics, and the retinal pigment epithelium patient pool. Pigment epithelial detachment is a significant retinal disorder, often associated with age-related macular degeneration (AMD), central serous chorioretinopathy (CSCR), and other retinal diseases, leading to a marked increase in prevalence among the elderly. The average age of patients with drusenoid retinal pigment epithelium is 77 years.
Discover evolving trends in the retinal pigment epithelium patient pool forecasts @ https://www.delveinsight.com/sample-request/pigment-epithelial-detachment-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=xpr
The report also examines the current and evolving retinal pigment epithelium treatment landscape. Intravitreal anti-VEGF agents, like AVASTIN (Roche), Ranibizumab, and Aflibercept, remain the cornerstone for treating vascularized PEDs associated with neovascular AMD. Combination therapies, particularly those that involve anti-VEGF agents alongside photodynamic therapy, such as, have shown promise for managing large or treatment-resistant pigment epithelial detachments.
ONL-1204, developed by ONL Therapeutics, is a novel, first-in-class small-molecule peptide currently in Phase II clinical trials for the treatment of pigment epithelial detachment. ONL-1204 works by inhibiting the Fas receptor to protect retinal cells and photoreceptors from apoptosis and preserve vision. In Phase I and II studies, ONL-1204 has demonstrated encouraging results, showing visual benefits, especially in patients at high risk of vision loss. The ongoing Phase II trial is evaluating two dosing regimens and will provide critical data to support further development towards pivotal Phase III studies.
Looking ahead, the pigment epithelial detachment treatment landscape is rapidly advancing, with significant progress in cell and gene therapy for retinal diseases, especially AMD. Research continues to refine techniques for retinal pigment epithelium transplantation, focusing on the development of new scaffolds and delivery methods to ensure proper oxygenation and cell adhesion for both RPE and outer retina cells.
Moreover, advancements in retinal imaging, such as Laser Doppler holography, are enhancing the visualization of blood flow and other retinal structures, which could improve diagnostics and treatment planning. In late 2024, machine learning algorithms for the automated detection of PEDs from optical coherence tomography images have shown promising results, with logistic regression models achieving over 96% accuracy.
In November 2025, LumiThera received FDA authorization to market its Valeda Light Delivery System, which is the first therapy utilizing photobiomodulation (PBM) to improve visual acuity in patients with intermediate AMD. This approval is based on data from the LIGHTSITE III trial (NCT04065490), which showed durable best-corrected visual acuity improvements of more than five letters maintained over 24 months. Additionally, research published in December 2024 highlighted the role of fatty acid desaturase 1 (FADS1) in RPE ferroptosis and AMD progression, identifying FADS1 inhibition as a potential therapeutic target, reflecting the active pace of development and market growth potential in PED treatments.
Unlock which retinal pigment epithelium emerging drug is expected to capture the largest market share in 7MM by 2032. Visit https://www.delveinsight.com/sample-request/pigment-epithelial-detachment-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=xpr
In conclusion, despite facing challenges such as immune rejection in allogeneic transplants, surgical complications, high production costs, and limited accessibility, the retinal pigment epithelium market is on a strong growth trajectory, fueled by an aging population, innovative therapeutic strategies, and rapid technological advancements in diagnostics and imaging.
With promising developments in anti-VEGF agents, photobiomodulation therapies, and emerging gene and cell therapies, the treatment approach for PED is shifting towards more targeted, effective, and personalized care. As leading players continue to invest in research, collaboration, and innovative pipelines, the PED market is well-positioned for substantial transformation.
Scope of the Pigment Epithelial Detachment Market Report
Study Period: 2020-2034
Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
Key Pigment Epithelial Detachment Companies
Key Pigment Epithelial Detachment Therapies
Pigment Epithelial Detachment Therapeutic Assessment: Pigment Epithelial Detachment current marketed and Pigment Epithelial Detachment emerging therapies
Pigment Epithelial Detachment Market Dynamics: Pigment Epithelial Detachment market drivers and Pigment Epithelial Detachment market barriers
Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
Pigment Epithelial Detachment Unmet Needs, KOL's views, Analyst's views, Pigment Epithelial Detachment Market Access and Reimbursement
Table of Contents
1. Key Insights
2. Report Introduction
3. Executive Summary
4. Pigment Epithelial Detachment Market Overview at a Glance
5. Epidemiology and Market Forecast Methodology
6. Key Events
7. Pigment Epithelial Detachment Background and Overview
8. Pigment Epithelial Detachment Treatment
9. Pigment Epithelial Detachment Epidemiology and Patient Population in the 7MM
10. Pigment Epithelial Detachment Patient Journey
11. Pigment Epithelial Detachment Marketed Drug
12. Pigment Epithelial Detachment Emerging Drugs
13. Pigment Epithelial Detachment: 7MM Analysis
14. Unmet needs
15. SWOT Analysis
16. KOL Views
17. Market Access and Reimbursement
18. Appendix
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight
Company Name: DelveInsight Business Research LLP
Contact Person: Arpit Anand
Email: info@delveinsight.com
Phone: +14699457679
Address: 304 S. Jones Blvd #2432
City: Las Vegas
State: Nevada
Country: United States
Website: https://www.delveinsight.com/
About DelveInsight
DelveInsight is a leading market research and consulting firm specializing in disease-specific insights and therapeutic market analysis. Their reports integrate real-world data, clinical trial findings, and expert interviews to deliver comprehensive industry intelligence.
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