HERG Screening Global Market Size, Share Report, Growth Prospects, Developments Plans, Future Insights and Trends Analysis Till 2033 | Merck KGaA, Crprotex Limited, ChanTest Corporation, Creative bioarray Inc., ChemAxon Ltd.

The HERG screening market size has grown rapidly in recent years. It will grow from $1.42 billion in 2023 to $1.62 billion in 2024 at a compound annual growth rate (CAGR) of 14.2%. The growth in the historic period can be attributed to increasing drug development activities, regulatory requirements, increasing awareness of cardiac safety, rising incidence of cardiac disorders.

The HERG screening market size is expected to see rapid growth in the next few years. It will grow to $2.60 billion in 2028 at a compound annual growth rate (CAGR) of 12.5%. The growth in the forecast period can be attributed to expansion of personalized medicine, increasing outsourcing of drug development activities, emerging markets and research, focus on non-cardiac safety assessments. Major trends in the forecast period include advanced in vitro models, integration of genomic and proteomic data, advancements in computational approaches, focus on pediatric drug safety, collaborations for data sharing and standardization.

Market Overview -
Human Ether-à-go-go-related gene (HERG) screening refers to the process of assessing the potential cardiotoxicity of a drug or compound. HERG screening is an important component of preclinical safety assessment in drug discovery and development, ensuring the safety and efficacy of novel therapeutic agents.

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Expanding HERG Screening Market Fueled By Increasing Prevalence Of Heart Disorders
The rise in the number of patients with heart disorders is expected to propel the growth of the HERG screening market going forward. Heart disorders, also known as cardiovascular disorders or diseases, refer to a range of conditions that affect the heart and blood vessels. These conditions can impact the heart's ability to function properly and may lead to serious health complications. These disorders arise because of unhealthy lifestyles, an aging population, genetic factors, diabetes, and metabolic syndrome. HERG screening helps to identify potential drug candidates, prevent adverse cardiac events that could induce life-threatening cardiac arrhythmias, particularly torsade de pointes (TdP), and improve patient outcomes. For instance, in May 2023, the Centers for Disease Control and Prevention., a US-based national public health agency, reported that in the US, 1 in 20 adults age 20 and older have cardiovascular diseases, 695,000 people were suffering from cardiovascular diseases in 2021, and 375,476 people died with cardiovascular diseases that same year. Furthermore, in March 2022, according to a report published by the Office for National Statistics, a UK-based government department, 19,440 people died of heart attacks in 2020, and this number increased to 20,061 in 2021. Therefore, the rise in the number of patients with heart disorders is driving the growth of the HERG screening market.

Competitive Landscape -
Major companies operating in the HERG screening market are Eurofins-Cerep SA., Aviva Biosciences Inc., AstraZeneca Public Limited Company, Merck KGaA, Charles River Laboratories Inc., Abcam Public Limited Company, Molecular Devices LLC, Caliper Life Sciences Inc., Crprotex Limited, ChanTest Corporation, Creative bioarray Inc., Cellular Dynamics International Inc., Nanion Technologies, Essen Bioscience, ABR-Affinity BioReagents Inc., ACEA Biosciences Inc., Metrion biosciences Inc., Aurora Biomed Inc., Aureus Sciences, RedShift BioAnalytics, B'SYS GmbH, Cambridge Bioscience Ltd., Sophion Bioscience Inc., Fluxion Biosciences Inc., ChemAxon Ltd.

Metrion Biosciences Ltd. Introduces GLP-Certified hERG Screening Service For Enhanced Cardiac Safety In Drug Development
Major companies operating in the HERG screening market are concentrating on new innovative advanced solutions, such as GLP-certified HERG screening services, to enhance cardiac safety assessments during drug development processes. This service refers to the good laboratory practice-certified screening of the human ether-à-go-go related gene (hERG) using the conventional whole-cell patch-clamp technique. It ensures that the screening is conducted in compliance with regulatory guidelines such as ICH S7A and ICH S7B, which are essential for safety pharmacology studies in drug development. For instance, in August 2023, Metrion Biosciences Ltd., a UK-based pharmaceutical company, launched the good laboratory practice (GLP)-certified hERG screening service. This service aims to enhance Metrion's support for small-molecule therapeutic development and complement the company's existing cardiac safety service portfolio. Additionally, this service utilizes the conventional whole-cell patch-clamp technique to assess potential cardiac liabilities before entering Phase 1 clinical trials in humans, provides regulatory guidance for safety pharmacology studies in drug development, and offers clients high-quality biology services for ion channel targets.

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Key Segments -
The HERG screening market covered in this report is segmented -
1) By Type: Gene KCNH2, Mutant KCNH2
2) By Ion Channel: Voltage-Gated, Ligand Gated
3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications

Key highlights covered in the report -
1. Detailed market size forecast and historical data analysis
2. Key drivers influencing market growth
3. Identification of upcoming trends and potential opportunities in the market
4. Analysis of major players strategies, to understand competitive dynamics and market positioning
5. Evaluation of regional dynamics

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