Postoperative infections after transplantation

Transplantation of organs has become a successful modality for treatment of organ diseases. Improved techniques for organ preservation, surgical procedures, rejection management, and posttransplant infection prophylaxis and treatment have contributed to this success. Most identifiable of the advances in solid organ transplantation (SOT) is the development of potent immunosuppressive agents. However, the use of these agents in the prevention and management of rejection is closely interrelated to the development of infection. Infection is the most important cause of early morbidity and mortality following transplantation. The development of prophylactic strategies for bacterial, viral, fungal, and protozoal organisms has contributed to a decrease in infectious complications and an increase in patient survival. However, the development and emergence of antimicrobial-resistant microbes (eg, vancomycin-resistant enterococci [VRE], methicillin-resistant Staphylococcus aureus [MRSA], penicillin-resistant pneumococci, ganciclovir-resistant cytomegalovirus [CMV], and azole-resistant Candida species); fungi (eg, Fusarium, Alternaria,and Scedosporium); and opportunistic bacteria (eg, Rhodococcus equi and Nocardia species) makes it necessary to get the best sterile conditions during operations to minimize the risk of postoperative infection. Currently, the most common infectious problems within the first month following transplantation are bacterial infections of the wound. They are associated with prolonged lengths of hospitalization and increased morbidity and mortality.

Toul instrument table maintains the sterility of the instruments even during long operations and reduces therefore the risk of an surgical site infection SSI. The toul instrument table provides a horizontal ultraclean laminar airflow which is directed directly over the instruments, acting as a barrier and minimizing the presence of bacteria-carrying particles at the instruments. It has been estimated that almost 70 % of bacteria found in patient’s wounds are transported indirectly via exposed instruments especially during long exposure time of instruments like in transplantation surgery.

Toul is equipped with a high-efficiency particulate air filter (Hepa H 14)and can be used to protect immunocompromised patients in case of the absence of clean rooms ( total protected environment (TPE) consisting of a high-efficiency-particulate-air (HEPA)-filtered laminar air flow room to prevent infections ( e.g. neutropenic patients). The unit is mobile and can be used in various rooms. No modification of existing hospital rooms is required.

Application
Heart transplantation
Lung transplantation
Kidney transplantation
kidney-pancreas transplantation
liver transplantation
bone marrow transplantation
All kind of solid-organ transplantation
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Normeditec
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39100 Bozen (Suedtirol)
Tel +39/348 730 24 45
Fax: + 39/0521/37 36 31
http://www.normeditec.com

Normeditec fights against the increase of hospital infections

This release was published on openPR.