Psychological Test and Assessment Modeling: PROMIS Fatigue measure items can be recommended for use in cancer populations
"Twelve of 14 PROMIS fatigue items performed well across the ethnically/racially diverse samples with minimal findings of different item functioning (DIF) that would have any effect on comparing or combining scores across cancer populations. Supporting evidence of the validity and reliability of the PROMIS measures will enhance the adoption of the measures in oncology clinical research."
Approximately 60% of cancer patients experience moderate to severe fatigue during active treatment. Cancer patients commonly describe their fatigue experience as very different from normal fatigue that most people experience. They were "drained" and felt "like a zombie". The qualitative study also found fatigue to have deleterious effects on their lives including cognitive impact ("my brain´s gone"), emotional impact ("depression", "frustration"), physical impact ("trouble keeping up with work", "too tired to get out of bed"), and social impact ("affects relationship with my kids, ... with my spouse, and ... my friends".
Observational studies with cancer patients have found fatigue to also co-occur with poor sleep quality, depressed mood and pain; forming a symptom cluster that severely impacts quality of life.
>> Psychological Test and Assessment Modeling Volume 58, Issue 1/2016
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