MoBiTec, Germany, Offers a New Range of Monofluorinated Nucleosides Manufactured by Dextra, UK

Fluorine introduction can lead to a modification of the reactivity of functional groups, alter conformational stability and, in pharmaceuticals, enhance metabolic stability. Over 30% of leading blockbuster drugs contain at least one fluorine atom.

MoBiTec is excited to present a new range of monofluorinated nucleosides, manufactured by its UK-based partner company Dextra Laboratories Ltd., Reading, UK. Dextra is a leading provider of carbohydrate analysis, synthesis and GMP manufacturing.

The introduction of a fluorine atom into a molecule is known to impart unique properties due to its highly electronegative nature and small size. Fluorine introduction can lead to modification of the reactivity of functional groups, alter conformational stability and in pharmaceuticals, enhance metabolic stability. The success which can been seen through incorporation of fluorine atoms into drugs is illustrated by the fact that over 30% of the leading blockbuster drugs contain at least one fluorine atom.

Dextra have an expert nucleoside team, with a proven track record in the provision of innovative solutions to new target molecules. They have extensive experience in the synthesis of nucleosides with modifications to both the sugar moiety and the nucleobase. They also have considerable experience in fluorination chemistry, successfully synthesising multiple (poly)fluorinated target molecules utilising a range of methods of fluorine introduction and exploiting the altered chemical reactivity of the substrates in the downstream chemistry.

The Dextra product catalog further comprises:

- Monosaccharides
- Imino Sugars
- Oligosaccharides
- Heparin & Chondroitin derived Oligosaccharides
- Maltooligosaccharides
- Blood Group Products
- Glycans
- Neoglycoproteins
- Neoglycolipids
- Polysaccharides
- Pharmaceutical Intermediates and Diagnostics
- Nucleosides
- Phosphorylated Sugars
- Umbelliferyls

In addition to the off-the-shelf product catalog Dextra also offers services with respect to synthesis, analysis, and GMP manufacturing.

MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.

In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.

MoBiTec GmbH
Arne Schulz
Lotzestr. 22a
37083 Goettingen, Germany

This release was published on openPR.