Adhesion Barriers Market Opportunities, and Trends in Coming Years

Adhesion Barriers Market Outlook 2031

The global adhesion barriers market was valued at US$ 1.0 Bn in 2021

The global market is projected to grow at a CAGR of 6.5% from 2022 to 2031

The global adhesion barriers market is anticipated to reach more than US$ 2.0 Bn by the end of 2031

Overview of Adhesion Barriers Market

Adhesion is a band of scar tissue that binds elements of a tissue. Adhesion can also be a skinny sheet of tissue akin to a plastic wrap or thick fibrous band. Adhesion barriers, including bodily barrier agents, separate injured tissues to prevent the formation of a fibrin bridge among tissues. Adhesion develops while the restore mechanisms of the body reply to any tissue disturbance, which includes surgery, infection, trauma, or radiation, ensuing an inflammation.

Adhesions could arise anywhere; however, the belly cavity, pelvis, and heart are the most common places. Seprafilm (sheet-type) and Adspray (gel-type) are the two types of adhesion barriers. Interceed absorbable adhesion barrier is required to reduce postoperative adhesion reformation in infertility and endometriosis surgery. The U.S. FDA has approved three adhesion barrier products: Interceed adhesion barrier, Seprafilm adhesion barrier, and Adept adhesion barrier.

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Radiation therapy for the treatment of various abdominal malignancies such as gynecological diseases, prostate, rectal, or lymphoproliferative disorders leads to the development of abdominal adhesion. Major players in the global adhesion barriers market such as Baxter, Anika Therapeutics, Inc. and Sanofi adopt synergistic approaches for the manufacture and distribution of products. Increase in geriatric population living with gynecological disorders is anticipated to augment the global adhesion barriers market.

High Rate of Adhesion to Drive Global Adhesion Barrier Market

Rise in incidence of post-operative adhesion is expected to be a key driver of the global adhesion barriers market. About 90% of individuals who undergo abdominal surgery, especially laparotomy, are prone to develop abdominal adhesion. The remaining 10% individuals do not develop abdominal adhesion barriers. The signs of laparotomy typically include complex appendectomy, small bowel problems, gastrointestinal cancer, hysterectomy, and ectopic pregnancy.

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More than 9 million abdominal and pelvic procedures are performed in the U.S. every year. The adhesion rate of C-section procedures is around 94%, while the adhesion rate of adhesiolysis and gastrointestinal surgery is between 65% and 75%. Non-surgical adhesions include inflammatory bowel disease, abdominal tuberculosis, and diverticular disorders. Endometriosis and pelvic inflammatory diseases are the most common causes of adhesion.

Increase in Usage of Adhesion Barrier Products across Globe

Surgeons across the world have increased the usage of adhesion barrier products in the past few years. In women, adhesions occur after postpartum gynecological surgeries, which cause prolonged discomfort, inflammation, infertility, and other gynecological diseases. This influences surgeons to choose adhesion barrier films during surgical procedures. Problems caused due to post-surgical adhesion have raised overall morbidity and treatment costs. North America has reported over 300,000 hospital admissions due to adhesive small intestinal obstruction, which accounted for 850,000 days of hospital admissions and cost over US$ 1.3 Bn.

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Non-reactivity, Non-toxicity, and Anti-thrombogenicity Properties to Propel Synthetic Adhesion Barriers Segment

In terms of type, the global adhesion barriers market has been bifurcated into natural adhesion barriers and synthetic adhesion barriers. The synthetic adhesion barriers segment accounted for major share of the global market in 2021. The segment is expected to grow at a high CAGR of from 2022 to 2031. Synthetic adhesion barriers include artificial gel film, Gelfoam, Silastic, Gore-Tex, Interceed (TC7), and Seprafilm. These are non-reactive, non-toxic, and anti-thrombogenic, with small pores that prevent the transmigration of cell tissue and adhesions.

Increase in Complexity of Intra-abdominal Operations to Bolster Abdominal Surgeries Segment

Based on application, the global adhesion barriers market has been classified into abdominal surgeries, gynecological surgeries, neuro surgeries, orthopedic surgeries, and others. The abdominal surgeries segment accounted for major share of the global market in 2021. Postoperative adhesions are estimated to affect more than 90% of patients undergoing abdominal or pelvic surgery. Adhesions can also cause chronic pain, infertility, and increase in the complexity of subsequent intra-abdominal operations. Thus, growth in usage of adhesion barriers in abdominal surgeries is projected to drive the segment.

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Decrease in Frequency, Extent, and Severity of Adhesions in Abdominal and Pelvic Cavities to Propel Film Segment

In terms of formulation, the global adhesion barriers market has been segregated into film, gel, and liquid. The film segment held the largest share of the global market in 2021. The segment is expected to grow at a high CAGR from 2022 to 2031 due to the rise in Seprafilm sales. In comparison to untreated controls, Seprafilm reduces the number of reoperations required for small bowel obstruction by 47%. Seprafilm is a sterile, bioresorbable, translucent adhesion barrier composed of two chemically modified polysaccharides: sodium hyaluronate (HA) and carboxymethylcellulose (CMC).

HA is a naturally occurring polysaccharide found in the human body. CMC, a polysaccharide, is a cellulose derivative. Seprafilm becomes hydrophilic and does not need to be sutured due to the properties of these ingredients. It stays where it is applied until absorbed. When used as directed, the Seprafilm adhesion barrier can be expected to reduce the frequency, extent, and severity of adhesions in abdominal and pelvic cavities. Seprafilm gels within 24 hours to 48 hours after placement.

Increase in Gynecological and Abdominal Surgical Procedures to Augment Hospitals Segment

Based on end-user, the global adhesion barriers market has been divided into hospitals, ambulatory surgical centers, and specialty clinics. The hospitals segment accounted for major share of the global market in 2021. Increase in gynecological and abdominal surgical procedures in hospitals is likely to drive the segment during the forecast period.

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Regional Outlook of Global Adhesion Barriers Market

North America dominated the global adhesion barriers market in 2021. The market in the region is projected to grow at a high CAGR from 2022 to 2031. This can be ascribed to the rise in number of surgeries in the U.S., surge in geriatric population, and increase in incidence of chronic diseases such as cancers and gynecological disorders.

Europe held the second largest share of the global market in 2021. Rest of Europe dominated the market in the region in 2021. Increase in research & development activities in adhesion barriers, such as development of new bioresorable polymer film to prevent peritoneal adhesions in post-surgical treatments, is expected to propel the market in Rest of Europe.

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 Analysis of Key Players in Global Adhesion Barriers Market

The global adhesion barriers market is consolidated, with the presence of small number of large companies. Expansion of product portfolio and mergers & acquisitions are the major strategies adopted by key players. Becton, Dickinson and Company, Allosource, Baxter International, Inc., Anika Therapeutics, Ethicon US, LLC., Hangzhou Singclean Medical Products Co., Ltd., Integra LifeSciences Corporation, PlantTec Medical GmbH, Sanofi, Innocoll, Terumo Corporation, and FzioMed, Inc. are the prominent players in the global adhesion barriers market.

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