How is Organ-on-Chip Technology Revolutionizing Medical Research?

A recent innovation in biomedical engineering, the organ-on-chip technology helps researchers overcome the limitations and constraints of the traditional two-dimensional cell culture processes and methodologies by enabling the development of models that mimic the 3D (three-dimensional) arrangement of various cell types in the human body more accurately. With the growing incidence of chronic diseases, the requirement for advanced treatment methods is rising rapidly. This is pushing up the requirement for alternatives to animal models in R&D (research and development).

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The use of the organ-on-chip technology allows researchers to overcome the constraints of medical research involving animal surrogates of human ailments, mainly in terms of their translatability to humans and scientific validity. Moreover, this technology helps researchers address the various complexities associated with animal models, which are usually used for disease model research and studies. As a result, many pharmaceutical companies are making huge investments in drug discovery and drug repurposing processes involving the use of organ-on-chip models.

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When application is taken into consideration, the organ-on-chip market is divided into physiological model development, drug discovery, and toxicology research. Amongst these, the drug discovery category is predicted to record rapid advancement in the market in the forthcoming years. Between the pharmaceutical and biotechnology companies and academic research institutes, the adoption of organ-on-chip technology is currently observed to be significantly high in the former, on account of the lucrative grants being provided to these companies for R&D activities.

Hence, it can be said with full confidence that the demand for organ-on-chip technology will shoot-up all over the world in the coming years, primarily because of the rising requirement for advanced and improved drug discovery methods, the growing need for better alternatives to animal models in medical research, and the soaring requirement for advanced technologies in healthcare research activities.

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