Moisture content on display
GEA Pharma Systems, in co-operation with NDC, has developed a new inline moisture sensor for pharmaceutical drying systems that drastically simplifies moisture measurement, saves processing time, avoids unnecessary operator contact with toxic compounds and helps ensure a top product quality.
The new moisture sensor, LHP-NDC 710e, which fits into a standard 2” port on the dryer, eliminates the need for complex chemical modelling techniques (chemometrics) to ascertain the moisture content of a product during the drying process. It extracts just the moisture content as a single piece of information and displays it simply for the operator. This speeds up the drying process and improves accuracy.
Using standard techniques, samples of dried powder must be taken manually from each batch of powder and tested off line in a laboratory to establish when the correct moisture contact has been achieved. This is time consuming, requires the dryer to be stopped and to wait while the test is performed, and runs the risk of the target moisture level being overshot producing a product that is too dry and difficult (or impossible) to handle efficiently. Validated systems are susceptible to many outside influences, such as atmospheric conditions, which means that the moisture level can vary even if the process itself is constant.
The new sensor from GEA Pharma Systems, however, shows a continuous display of the actual moisture content on a display screen as the product dries. This allows the operator to monitor precisely the actual moisture content and to stop the drying at exactly the right point. There is no need to wait for results, no chance of over-drying the product, and the operator never has to come in direct contact with the product.
In addition the standard technique only provides a snapshot of the condition of a limited amount of product (5-10grams). The in-line moisture sensor, however, is capable of monitoring the complete drying cycle. The total amount of analysed product during the process cycle is estimated to be more than 1000 grams. This will enable the operator to gain an understanding of the complete process cycle and so continuously improve the production process as well as anticipate unplanned events.
When first installing the LHP-NDC 710e it is necessary to perform a simple calibration exercise to compare the reading on the sensor to actual readings from laboratory tests. These need to be done for each product to be dried. Once the calibration line has been plotted for each product the instrument remembers the settings and continues to show accurate moisture levels for each product. As this is a display of the actual moisture level in the powder it is unaffected by atmospheric conditions or other variables.
The Lighthouse Probe™, also from GEA Pharma Systems, is particularly useful when working with wet or sticky products when it is essential to ensure a clear view of the product. Conventional windows can easily become fouled when processing these types of products. The Lighthouse Probe™ uses an in-line window wash to keep a clear view at all times. Further features are the in-line calibration as well as end-of-process full CIP (Clean-in-Place), which makes it suitable for use in a GMP environment.
Dr. Harald Stahl, Senior Pharmaceutical Technologist, with GEA Pharma Systems said that the time savings for each product batch could be very significant. “Every time a batch is tested manually it can take 10-15 minutes. Sometimes batches have to be tested more often. The real risk is that the final moisture content is too low. In this case it’s possible that the whole batch could be rejected. The new sensor avoids this problem and ensures that the target moisture content is achieved every time.”
The LHP-NDC 710e is simple to install and can be ready for calibration in just 20 minutes. It allows the moisture content of any powder product to be adjusted as required.
GEA Pharma Systems is part of the GEA Group and a specialist in powder handling machinery for the pharmaceutical sector. Products include: tablet presses, granulation and agglomeration equipment, high containment valves, bulk handling equipment, and freeze drying systems for pharmaceuticals.
All editorial enquiries to:
The Words Workshop Ltd
26 Swanwick Lane, Broughton, Milton Keynes, MK10 9LD
Tel: +44 1908 695500
All business enquiries to:
Tomas Vermeire - Senior Process Technologist - Lighthouse Probe Product Manager
GEA Pharma Systems
Tel: +32 (0) 3 350 1258
This release was published on openPR.
Permanent link to this press release:
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.
You can edit or delete your press release Moisture content on display here
News-ID: 212463 • Views: …
More Releases from GEA Pharma Systems
Janssen Pharmaceutica teams up with GEA Pharma Systems to investigate continuous …
Janssen Pharmaceutica, part of the worldwide Janssen Pharmaceutica Group, has initiated a global project with the aim of evaluating technical performance and related business benefits of continuous processing technologies for oral solid dosage forms. In this context, ConsiGma™ continuous processing technology from GEA Pharma Systems has been assessed for tablet manufacture. During an in-depth feasibility study at GEA Pharma Systems’ lab, the team from Janssen has been able to
GEA Pharma Systems presents European granulation, drying, tableting and fermenta …
GEA Pharma Systems will be exhibiting at CHINA-PHARM 2012 from 24 to 27 September at the China National Convention Center in Beijing. Exhibits on stand number 3017 will include examples of the company’s range of Aeromatic-Fielder™ and Collette™ granulation and drying plant; MODUL™ tablet presses from Courtoy™; and pharmaceutical fermentation systems from GEA Diessel showing state-of-the-art technology for a bioreactor vessel. On 25 September the company will present a
Combined pharmaceutical freeze drying service proves a success in China for GEA …
It was in November 2010 that GEA Pharma Systems acquired Beijing Sino-German Tianhe Technology in Beijing to create GEA Lyophil (Beijing) Ltd. Since then, the company has quadrupled turnover and enhanced its customer service by blending German quality and Chinese economy to provide a unique combined offering to its pharmaceutical clients. Jinbin Tang, MD, GEA Lyophil (Beijing) Ltd. said that the market had changed in China since the introduction of new
GEA Pharma Systems wins large order for continuous solid dose processing from ma …
GEA Pharma Systems has announced an agreement with a US pharmaceutical company to supply a complete continuous processing line for the production of solid dose drugs. The order is one of the more significant for ConsiGma™ oral solid dosage continuous processing equipment and represents the first phase of a potentially long-term commitment for this customer. Delivery is scheduled for early 2013. The order is to deliver a continuous solid
More Releases for Inline
Inline Heaters Market Size And Forecast-2022-2029
The research study on the global Inline Heaters market covers industry sectors, market climate, emerging innovations, competitive intelligence, and current developments in the industry. The sector study investigates the business dynamics of the rising economy, as well as current driving forces, market conditions, risks, trends, and problems. The analysis identifies the exact impact on the revenue and demand due to the disturbances caused by the occurrence of COVID-19. The recently
Inline Viscosity Sensors Market 2021 | Detailed Report
According to Market Study Report, Inline Viscosity Sensors Market provides a comprehensive analysis of the Inline Viscosity Sensors Market segments, including their dynamics, size, growth, regulatory requirements, competitive landscape, and emerging opportunities of global industry. An exclusive data offered in this report is collected by research and industry experts team. Get Free Sample PDF (including full TOC, Tables and Figures) of Inline Viscosity Sensors Market @ https://www.reportsnreports.com/contacts/requestsample.aspx?name=5048562 The report provides a
Inline Monitoring Market 2028 | Emerson Electric, LMI Technologies
Inline Monitoring Market – Introduction Inline monitoring refers to the use of stationary sensors mounted outright in the industrial process for sensing the variables such as viscosity, density, color, temperature, or pH level. Unmatched efficiency of inline monitoring to measure the shifting parameters in real time aids in the detection and damage control of produced goods, which aids in saving significantly on the production cost. Get Sample Copy of the Report @ https://www.tmrresearch.com/sample/sample?flag=B&rep_id=5432 Inline
Inline Automated Optical Inspection Global Market 2018-2025
Press Release – 17 Jan 2019 Research and Development News -- . . Latest Update "Global Inline Automated Optical Inspection Market Insights, Forecast to 2025" with Industries Survey | Global Current Growth and Future. ' ' The Inline Automated Optical Inspection market was valued at xx Million US$ in 2017 and is projected to reach xx Million US$ by 2025, at a CAGR of xx% during the forecast period. In this study, 2017 has
Inline AOI Systems Market - Growth of Inline Aoi System Market Is Boosted By Inc …
Automated optical inspection (AOI) is a process of visual inspection which is operated automatically to detect different manufacturing defect such as catastrophic failure and quality defect. This technology is adopting by different types of manufacturer such as printed circuit board manufacturing, liquid - crystal display (LCD) manufacturing, transistor manufacturing, others. Moreover, AOI systems has been segmented in two types such as desktop AOI and Inline AOI systems. Inline AOI
New ParticleTrackTM E25 provides accessible inline characterization
A new inline characterization tool from METTLER TOLEDO provides a simple, effective method for robust in situ aqueous chemistry particle system tracking, helping to enhance optimization and reduce quality control costs in labs and production environments across a wide range of industries. METTLER TOLEDO is pleased to announce the launch of its new inline particle system characterization tool ParticleTrackTM E25. Modifying focused beam reflectance technology (FBRM®) for use in settings where