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Interleukin-6 (IL-6) Inhibitors Analysis, Clinical Trails and Developments

03-05-2020 04:13 PM CET | Health & Medicine

Press release from: Pharma Proff

Interleukin-6 (IL-6) Inhibitors Analysis, Clinical Trails

Interleukin-6 (IL-6) inhibitors currently exhibit a proliferating pipeline with 25+ therapeutic candidates.

IL-6 is a cytokine encoded by IL-6 gene, which helps in the maturation of B cells and is actively involved in the inflammatory response. The IL-6 protein is primarily produced at the sites of acute and chronic inflammation, where it is secreted into the serum and brings a transcriptional inflammatory response through IL-6? receptor. This protein is assumed to be actively involved in pyrogenesis, cancer, rheumatoid arthritis, diabetes mellitus, and schizophrenia. The IL-6 inhibitors target the IL-6 receptors, thereby blocking the signaling pathway between receptors and mediators of inflammation that stimulate the accumulation of B cells.

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According to the research, drugs being developed as IL-6 inhibitors, most of which are in clinical phases and can be expected to be given orally. It has been observed that the oral route of medications is convenient, available in delayed or rapid release formulation, less risk of systemic infections, and inexpensive in nature, and also provides improved patient's compliance.

Some of the companies involved in the development of IL-6 inhibitors include F. Hoffmann-La Roche Ltd., Regeneron Pharmaceuticals Inc., Sanofi-aventis Groupe, Janssen Global Services LLC, Novimmune SA, UCB Pharma.

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IL-6 Inhibitors Pipeline Analysis
o By Phase
o By Molecule Type
o By Route of Administration
o By Company

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Pharma Proff, a brainchild of Prescient & Strategic (P&S) Intelligence Private Limited, is a frontline market intelligence and consulting solutions provider catering to the information and data needs of burgeoning sectors across the world, including pharmaceutical and healthcare. With meticulously curated research reports on the industry landscape, we empower companies in the healthcare and pharmaceutical sectors to make informed business decisions and base their marketing strategies with astuteness.

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