Immune Check Point Inhibitors Market Immune Check Point Inhibitors Clinical Pipeline Report 2022

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Report Table of Contents

Immune Checkpoint Inhibitors- Introduction to Next Generation Cancer Immunotherapy
1.1 Overview
1.2 History- From Tragedy to Breakthrough

Major Immune Checkpoints Proteins
2.1 Role of Cytotoxic T lymphocyte Antigen-4 (CTLA-4) in Cancer Development
2.2 Role of Programed Cell Death Protein 1 (PD1) in Cancer Development

Mechanism of Action of Immune Checkpoint Inhibitors
3.1 Cytotoxic T lymphocyte Antigen-4 (CTLA-4)
3.1 Programed Death Protein-1 (PD1)

CTLA 4 Inhibition Approved Drugs to Target Immune Checkpoints
4.1 Ipilimumab (Yervoy: Melanoma)

PD-1 and PD-L1 Inhibition Approved Drugs to Target Immune Checkpoints
5.1 Nivolumab (Opdivo: Hodgkin Lymphoma, Urothelial Carcinoma and NSCLC)
5.2 Pembrolizumab (Keytruda: Melanoma and NSCLC)
5.3 Atezolizumab (Tecentriq: Solid Tumors)

Biomarkers Associated with Immune Checkpoint Inhibitors
6.1 Predictive Biomarkers to Anti-CTLA 4
6.2 Predictive Biomarker to Anti-PD 1

Combination Approaches with Immune Checkpoint Inhibitors
7.1 Combination with Conventional Methods
7.1.1 Chemotherapy
7.1.2 Targeted Therapies
7.1.3 Radiotherapy
7.2 Combination with Cancer Vaccines
7.2.1 Peptide Vaccines
7.2.2 Cellular Vaccines
7.2.3 Oncolytic Viruses

Global Immune Checkpoint Inhibitors Market

Global Immune Checkpoint Inhibitors Clinical Pipeline
9.1 CTLA-4-Inhibitors Pipeline Overview
9.2 PD-1-Protein-Inhibitors Pipeline Overview
9.3 PD-1-Protein-Inhibitors Pipeline Overview

Global Immune Checkpoint Inhibitors Market Dynamics
10.1 Favorable Parameters
10.2 Challenges to Market Growth

Future Potential of Immune Checkpoint Inhibitors
11.1 Current Therapeutic Eminence
11.2 Upcoming Market Opportunities

PDL1-Protein-Inhibitors Clinical Pipeline by Company, Indication and Phase
12.1 Research
12.2 Preclinical
12.3 Clinical
12.4 Phase-I
12.5 Phase-I/II
12.6 Preregistration

Marketed PDL1-Protein-Inhibitors Clinical Insight by Company and Phase
13.1 Pembrolizumab (Keytruda)
13.2 Atezolizumab (TECENTRIQ)

CTLA-4-Inhibitors Clinical Pipeline by Company, Indication and Phase
14.1 Research
14.2 Preclinical
14.3 Phase-I
14.4 Phase-III

Marketed CTLA-4-Inhibitors Clinical Insight by Company, Phase and Indication
15.1 Ipilimumab (Yervoy)

PD-1-Protein-Inhibitors Clinical Pipeline by Company, Phase and Indication
16.1 Research
16.2 Preclinical
16.3 Phase-I
16.4 Phase-I/II
16.5 Phase-II
16.6 Phase-II/III

Marketed PD-1-Protein-Inhibitors Clinical Insight by Company and Phase
17.1 Pembrolizumab (Keytruda)

Competitive Landscape
18.1 Advaxis
18.2 Agenus
18.3 Amgen
18.4 Bristol Myers Squibb
18.5 Faron Pharmaceuticals
18.6 Genentech
18.7 Genocea
18.8 Incyte Corporation
18.9 Innate Pharma
18.10 Kite Pharma
18.11 MacroGenics
18.12 Merck
18.13 NewLink Genetics Corp
18.14 Sorrento Therapeutics
18.15 TG Therapeutics

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Neeraj Chawla
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KuicK Research
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