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Hepatorenal Syndrome Therapeutics Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments | Cumberland Pharmaceuticals, NOORIK BIOPHARMACEUTICALS LIMITED

07-26-2019 02:44 PM CET | Health & Medicine

Press release from: Pharma Proff

Hepatorenal Syndrome Therapeutics-Pharma Proff

Hepatorenal Syndrome Therapeutics-Pharma Proff

Hepatorenal syndrome (HRS) is a reversible functional renal impairment, that occurs in patients with advanced liver cirrhosis or those with fulminant hepatic failure. It is characterized by a marked reduction in glomerular filtration rate and renal plasma flow, in the absence of other causes of renal failure.

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The symptoms of hepatorenal syndrome are fatigue, abdominal pain, malaise, ascites, jaundice, splenomegaly, and hepatomegaly. There are two sub-types of this disease; type 1 and type 2 hepatorenal syndrome.

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Type 1 hepatorenal syndrome is a rapidly progressive renal failure, defined by doubling of initial serum creatinine to a level >2.5 mg/dl or by a 50% reduction in creatinine clearance to a level

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