Press release
Mass Spectrometric Quantification of Proteinaceous Active Substances from Plants
26.10.2010PANATecs, the specialist for mass spectrometric-based protein analysis, has developed a quantitative analysis of a proteinaceous active substance for herbal medicines, for biosyn, a pharmaceutical company based in Fellbach by Stuttgart*.
Proteins are normally quantified with immunoassays. However, an alternative method had to be selected for the quantification of mistletoe lectin I, because of misleading cross-reactions with other lectins. Moreover, this new method would have to be in accordance with the requirements for drug registration.
This was why the Stuttgart firm biosyn decided to develop a mass spectrometric quantification method in collaboration with PANATecs. This method turned out to be extremely sensitive, even with concentrations in the lower nanogram range. Validation showed that the intraday precision was very high.
This mass spectrometric method can be used, for example, for the precise determination of protein concentrations during biotechnological production, even when classical methods, such as immunoassays, are inapplicable.
*See too the scientific article in the GIT Labor-Fachzeitschrift 10/2010, pp. 746-747, GIT Verlag GmbH & Co. KG, Darmstadt.
PANATecs GmbH
Vor dem Kreuzberg 17
72070 Tübingen
info@panatecs.com
Tel.: +49 7071-92058-0
www.panatecs.com
If you wish further information about this announcement, please contact:
Petra Finkbeiner, PANATecs GmbH,
Tel.: +49 7071-92058-18, pfinkbeiner@panatecs.com
PANATecs GmbH is a young and innovative service provider for the pharmaceutical, biotechnology and biotechnology industries. PANATecs employs high technology based on mass spectrometry to characterize the drugs of the future, which are to be used for the treatment of diseases which are difficult to cure. PANATecs has set itself the objective of becoming the market leader in service provision in protein analysis and will continue to expand its international business during 2010.
PANATecs is a spinoff from Tübingen University and celebrated its fifth birthday in 2009. PANATecs' team of highly qualified scientists supports technological progress in the life sciences industry.
The company is certified according to ISO 9001. Since March 2010, PANATecs has held the Manufacturing Authorization for Test Laboratories according to §13 of the German Medicines Act, including GMP certificate.
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