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Engaged in Sphingolipid Research? Check Out Echelon's New S1P antibody Z-P300!

08-15-2018 05:37 PM CET | Health & Medicine

Press release from: MoBiTec GmbH

Engaged in Sphingolipid Research? Check Out Echelon's New S1P

Sphingosine 1-Phosphate (S1P) is a key component of the sphingolipid signaling cascade.

Recently, scientific literature has suggested that S1P is a potent tumorigenic growth factor that is likely released from tumor cells and that S1P may be a novel biomarker for early stage cancer detection.

Sphingosine kinase has also been shown to be up-regulated in a variety of cancer types. S1P antibody (LT1002) was originally developed and patented at Lpath Therapeutics. Echelon Biosciences has further developed and validated the exciting new antibody Z-P300 for in vitro and cell-based applications.

Validated for use in:
IHC
ELISA

References
1) Visentin B, Reynolds G, Sabbadini R. (2012) Immunohistochemical detection of sphingosine-1-phosphate and sphingosine kinase-1 in human tissue samples. Methods Mol Biol. 874:55-67.

2) O'Brien N, Jones ST, Williams DG, Cunningham HB, Moreno K, Visentin B, et al. (2009) Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies. J Lipid Res.;50(11):2245-57.

3) Swaney JS, Moreno KM, Gentile AM, Sabbadini RA, Stoller GL. (2008) Sphingosine-1-phosphate (S1P) is a novel fibrotic mediator in the eye. Exp Eye Res.;87(4):367-75.

All Echelon products can be ordered from MoBiTec: http://www.mobitec.com

Contact info@mobitec.com for more information and bulk pricing options.

About MoBiTec GmbH

MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.

In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.

MoBiTec GmbH, Lotzestr. 22a, 37083 Goettingen,
Germany, info@mobitec.com, www.mobitec.com

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