Global Study on Factor XIII Deficiency Treatment Market and Growth Analysis Covering Drivers, Market Segments, New Technology, Cost Structure and Trends Forecasted during 2018 to 2028

Factor XIII deficiency is a rare genetic blood disorder that is characterised by the deficiency of clotting factor XIII. Clotting factors are proteins that play an important role in blood clotting. Patients suffering from factor XIII deficiency are able to form clots, however, these clots are highly unstable and dissolve easily, which results in prolonged uncontrolled bleeding. The severity and symptoms of the factor XIII deficiency varies from person to person thus the factor XIII deficiency treatment differs with respective to the severity. In most patients with factor XIII deficiency (80%), bleeding symptoms appear after birth, which include bleeding from the umbilical stump. Other patients are likely to have only a mild expression of the factor XIII deficiency that can become more apparent in the later stages of life when they encounter a traumatic injury or surgery.

Factor XIII deficiency is a genetic disorder that is recessive in nature. Thus, the risk of two carrier parents passing both the altered genes to their offspring is about 25% with each pregnancy. In case the parents are close relatives of each other, the risk is much higher. Thus, in communities where consanguineous marriages are more common, the risk of factor XIII deficiency is higher in the offspring, hence, it is widely seen in such communities.

Report Highlights:

• Detailed overview of parent market
• Changing market dynamics in the industry
• In-depth market segmentation
• Historical, current and projected market size in terms of volume and value
• Recent industry trends and developments
• Competitive landscape
• Strategies of key players and products offered
• Potential and niche segments, geographical regions exhibiting promising growth
• A neutral perspective on market performance
• Must-have information for market players to sustain and enhance their market footprint.

Ask our Industry Expert on this Report- https://www.factmr.com/connectus/sample?flag=AE&rep_id=1348

Factor XIII deficiency treatment involves the usage of factor XIII concentrates. Fresh frozen plasma is one of the most common factor XIII deficiency treatments, especially in regions where the pharmaceutical version of factor XIII concentrates are not available easily. However, cryoprecipitates are no longer recommended for factor XIII deficiency treatment because of the risk of infections from viruses and other similar pathogens. The risk of allergy is also likely with other unknown factors present in the cryoprecipitates. Individuals with factor XIII deficiency are recommended to undergo preventive factor XIII deficiency treatment that includes the use of factor XIII concentrate every 3-4 weeks. The prophylactic factor XIII deficiency treatment is mainly used to prevent bleeding in the brain.
In extremely rare cases, factor XIII deficiency may be caused due to the development of autoantibodies. These autoantibodies are also called inhibitors since they mistakenly attack replacement factor XIII that is used for the factor XIII deficiency treatment. In case the factor XIII deficiency treatment results in the formation of autoantibodies, additional therapy is required along with the factor XIII deficiency treatment. These additional therapies include the usage of immune suppressant drugs.

In 2011, CSL Behring received FDA approval for its Corifact (FXIII Concentrate) for the routine prophylactic factor XIII deficiency treatment. Similarly, in 2014, Novo Nordisk, Inc. received FDA approval for Tretten, a recombinant factor XIII replacement product. Tretten was approved for the prevention of bleeding in adults and children due to factor XIII A-subunit deficiency. Factor XIII deficiency treatment using recombinant technology is a popular topic for research since it is artificially created and does not contain human blood components, thereby resulting in no risk due to blood-borne viruses or similar other pathogens.

Factor XIII Deficiency Treatment Market: Drivers and Restraints

The significant presence of communities that follow consanguineous marriages increases the risk of passing on factor XIII deficiency to the next generations, which is driving the factor XIII deficiency treatment market. Increasing government support for the treatment of rare diseases such as the factor XIII disease treatment is also an important factor driving the factor XIII deficiency treatment market. However, lack of experience of skilled personals for the factor XIII deficiency treatment like other rare diseases along with the difficulties encountered during the R&D of factor XIII deficiency treatment are some of the factors expected to hamper the growth of the factor XIII deficiency treatment market during the forecast period.

To know more about the Factor XIII Deficiency Treatment Market Trends, Visit the link – https://www.factmr.com/report/1348/factor-xiii-deficiency-treatment-market

Factor XIII Deficiency Treatment Market: Segmentation
The global factor XIII deficiency treatment market can be segmented on the basis of treatment distribution channel and geography.

Based on treatment type, the global factor XIII deficiency treatment market is segmented as:
• Fresh frozen plasma treatment
• Pharmaceutical product treatment

Based on distribution channel, the global factor XIII deficiency treatment market is segmented as:

• Hospital pharmacies
• Retail pharmacies
• Blood banks

Factor XIII Deficiency Treatment Market: Overview

The global factor XIII deficiency treatment market is largely driven by the significant presence of consanguineous marriages. The factor XIII deficiency treatment that was used in the past involved the usage of fresh frozen plasma. However, due to the risk of infections, this form of treatment is not preferred. Recombinant technology-driven research resulted in products, such as Tretten, a recombinant factor XIII A-subunit, which are now more preferred since they are completely lab-synthesized products. The administration of these products for factor XIII deficiency treatment must be carried out at regular intervals for the prevention of bleeding especially in the brain.

Factor XIII Deficiency Treatment Market: Regional Outlook

Based on epidemiology, factor XIII deficiency cases are more frequent in regions where consanguineous marriages are more common. Thus, the occurrence of the disorder is most frequent in the Middle East and Africa region. However, a large number of cases go undiagnosed in these regions. Furthermore, the factor XIII deficiency treatment market has the highest potential in the MEA. Regions such as Canada, Brazil, Mexico and China also among the most lucrative regions for the factor XIII deficiency treatment. Europe and Australia have the lowest epidemiology, owing to which the treatment rate for the factor XIII deficiency treatment is low.

Factor XIII Deficiency Treatment Market: Key Players

The global market for factor XIII deficiency treatment has two main pharmaceutical players, however, there are a number of blood banks that offer fresh frozen plasma. Companies that offer factor xiii concentrate are CSL Behring and Novo Nordisk, Inc. Examples of some of the blood banks that offer fresh frozen plasma for factor XIII deficiency treatment are Global Blood Fund, World Blood Bank and other local blood banks.

The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.

The report covers exhaustive analysis on:

• Market Segments
• Market Dynamics
• Market Size
• Supply & Demand
• Current Trends/Issues/Challenges
• Competition & Companies involved
• Technology

Regional analysis includes

• APEJ
o Greater China
o India
o Korea
o ASEAN Countries
o Rest of APEJ
• Japan
• CIS & Russia
• Latin America
o Brazil
o Mexico
o Argentina
o Chile
o Peru
o Rest of LATAM
• North America
o US
o Canada

Pre-book this Report- https://www.factmr.com/checkout/1348/S

About FactMR
FactMR is a fast-growing market research firm that offers the most comprehensive suite of syndicated and customized market research reports. We believe transformative intelligence can educate and inspire businesses to make smarter decisions. We know the limitations of the one-size-fits-all approach; that's why we publish multi-industry global, regional, and country-specific research reports.

Contact Us
FactMR
11140 Rockville Pike
Suite 400
Rockville, MD 20852
United States
Email: sales@factmr.com
Web: https://www.factmr.com/

This release was published on openPR.