Press release
HYDROP and HYDROP-EX, New Fluorescent Reagents to Detect and Measure Hydrogen Peroxide
HYDROP- Mode of action
HYDROP is a fluorescent probe for specific detection of hydrogen peroxide (H2O2). It has low reactivity with other reactive oxygen species (ROS). While HYDROP is used for live-cell imaging, HYDROP-EX is for detection and quantification of hydrogen peroxide in solutions. HYDROP and HYDROP-EX are manufactured by Goryo Chemical, Japan, and distributed in Germany and other European countries by MoBiTec GmbH.
Features
• It fluoresces upon reaction with H2O2, but does not react with other ROS such as hydroxyradical (・OH), superoxide (O2－・), hypochlorous acid (HOCl), singlet oxygen (1O2), and nitric oxide (・NO).
• Cell-permeable HYDROP is a diacetylated form of HYDROP-EX. Initially, HYDROP has low reactivity with H2O2 but it is quickly hydrolyzed by intracellular esterases to generate reactive and cell-impermeable HYDROP-EX. Thus, generated HYDROP-EX remains within a cell and fluoresces upon reaction with H2O2.
Specifications
Excitation max: 492 nm
Emission max: 516 nm
Photostability: low
Brightnes: high
For details on HYDROP see: http://goryochemical.com/english/products/rosfluor/hydrop.html
About MoBiTec GmbH
MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.
In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.
MoBiTec GmbH, Lotzestr. 22a,
37083 Goettingen, Germany
info@mobitec.com
www.mobitec.com
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