Press release
Ultra-Precise 3D Printing Can Help Drug Testing for Treating Brain Disorders
SEM close-up view of one single tubular porous structure of the biomimetic microfluidic system (IIT)
Researchers of the Smart Bio Interfaces group at the IIT in Pontedera (Pisa, Italy) created the first biohybrid device mimicking the blood-brain barrier by means of a Nanoscribe 3D printer. The understanding of the blood-brain barrier mechanisms is target of biomedical investigations that deal with the treatment of several disorders in the central nervous system such as Alzheimer’s disease, multiple sclerosis and brain tumors.
Many drugs that are aimed to reach the brain are not able to penetrate the blood-brain barrier which acts as a membrane to protect the brain from pathogens. Nanoscribe’s direct laser writing systems Photonic Professional GT allow for the fabrication of ultra-precise 3D complex structures that help shape microfluidic models, e.g., resembling biological ones. The biomimicking device developed in this work consists of 3D printed artificial components and endothelial cells and will enable future drug testing.
The detailed press release by IIT can be found here: https://www.nanoscribe.de/en/media-press/press-releases/iit-istituto-italiano-di-tecnologia-first-hybrid-nanotech-device-mimicking-blood-brain-barrier/
Caption (© A.Marino, Smart-Bio-Interfaces, IIT Pontedera)
Img 1: SEM close-up view of one single tubular porous structure of the biomimetic microfluidic system 3D printed by means of a Nanoscribe system.
www.iit.it
www.nanoscribe.com
About Nanoscribe
The supplier of 3D printers for nano- and microfabrication has established itself as technology and global market leader with its laser lithographic processes. Based on the technique of two-photon polymerization, the Photonic Professional GT systems enable the fabrication of highest-resolution and ultra-complex 2D, 2.5D, and 3D nano- and microstructures for scientific and industrial applications. Renowned universities and top research institutes use the award-winning systems in more than 30 countries. Nanoscribe´s portfolio is complemented by tailor-made resins and process solutions. The medium-sized company was founded in 2007 as a spin-off from the Karlsruhe Institute of Technology (KIT).
Nanoscribe GmbH
Media Contact
Anke Werner
Hermann-von-Helmholtz-Platz 1
76344 Eggenstein-Leopoldshafen
Germany
Fon: 0049 (0)721 981980501
E-Mail: werner@nanoscribe.com
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