Global Epigenetics Market: Market Estimation, Dynamics, Regional Share, Trends, Competitor Analysis 2012-2016 and Forecast 2017-2023

Epigenetics is a study of heritable changes in gene expression which involves change in phenotype without changing genotype, which in turn affects reading of genes by cells. Epigenetic changes are natural and regular processes but also influenced by various factors like lifestyle, environment, age and state of disease. Epigenetic modifications can manifest a common manner of cells which differentiate terminally to end up as liver cells, skin cells, brain cells etc. Epigenetic change may have more damaging effects which can lead to diseases like cancer. Systems like histone modification, non-coding RNA-associated gene silencing and DNA methylation are considered for initiation of epigenetic change sustainably.


Surge in prevalence of cancer, improving funds and aids for the R&D activities, rise in the partnerships between pharmaceutical and biotechnology companies and research institutes, increase in epigenetics application in non-oncology diseases will propel the epigenetics. Moreover, improved advancements in epigenetics technology, untapped potential of emerging markets like India and China are expected to offer many opportunities for the growth of epigenetics market. However, high instrument cost and dearth of skilled personnel are expected to hamper the growth of the epigenetics market.


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The Epigenetics Market is classified on the basis of Enzymes, kits and assays, instruments, application, end user, and geography.

Based on Enzymes, the Epigenetics Market is segmented into the following

• DNA polymerase
• Acetylases
• DNA ligases
• Methyl transferase
• RNA ligases
• Reverse Transcriptase
• Others


Based on Instruments, the Epigenetics Market is segmented into the following

• Next generation sequencers
• Mass spectrometers
• Sonicators
• qPCRs
• Others


Based on Application, the Epigenetics Market is segmented into the following

• Oncology
• Cardiovascular diseases
• Metabolic diseases
• Inflammatory diseases
• Infectious diseases

Based on Kits and assays, the Epigenetics Market is segmented into the following

• Deep sequencing kit
• Bisulfate conversion kit
• Methyl transferase assays
• Chip- seq kits
• Immuno precipitation kits
• Histone assay

Based on End user, the Epigenetics Market is segmented into the following

• Pharmaceutical and biotechnological companies
• Contract research companies
• Academic and Research institutes

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Epigenetics has triggered R&D for new drugs for various cancers, chronic and autoimmune disorders. For example, U.S.FDA approved ramucirumab/Cyramza by Eli Lilly for use in combination with folfiri to treat metastatic colorectal cancer and Novartis’s Farydak and Celgene’s Istodax received FDA approval in 2015. Introduction of advanced technologies and potential investments on R&D activities are expected to fuel the growth of epigenetics. Currently, companies are focussing on detection of DNA methylation patterns and histone modification. For example, Epigenomic’s EPI ProColon 1.0, Quest Diagnostic’s ColoVantage, Abbott’s Real Time mS9 are few tests which detect SepT9 DNA methylation biomarker for colorectal carcinoma.

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Geographically Epigenetics Market is segmented as Latin America, Europe, Asia- Pacific, North America, The Middle East & Africa. North America is expected to account for largest market share in regional market of epigenetics due to rise in prevalence of cancer, high funding on R&D, increasing acquisitions and collaborations along large pharma companies, high adaptation and awareness of new technologies and healthcare infrastructure.


Some of the players in epigenetics market Illumina, Inc. (U.S.), Abcam plc. (U.K), QIAGEN N.V. (Netherland), New England Biolabs, Inc. (U.S.), Merck & Co. (U.S.), Sigma-Aldrich Corporation (U.S.), Genedata AG(Switzerland), Cayman chemical company (U.S), Active Motif (U.S.), Thermo Fisher Scientific, Inc., (U.S.), Diagenode, Inc. (Belgium), Zymo Research Corporation (U.S.). and Episona Inc. (U.S).

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