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Nucleic Acid Therapeutics Market Trends Emphasizing Epigenetic and microRNA Modulating Therapies

11-21-2025 10:05 AM CET | Health & Medicine

Press release from: Insightace Analytic Pvt Ltd.

Nucleic Acid Therapeutics Market

Nucleic Acid Therapeutics Market

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Global Nucleic Acid Therapeutics Market - (By Technology (RNA targeted therapeutics, Gene Therapies, Epigenetic and microRNA modulating therapies, Genome editing therapies, Others), By Application (Autoimmune Disorders, Genetic Disorders, Infectious Diseases, Cancer, Others), By End User (Hospitals & Clinics, Academic & Research Institutes, Others)), Trends, Industry Competition Analysis, Revenue and Forecast To 2031."

According to the latest research by InsightAce Analytic, the Global Nucleic Acid Therapeutics Market is valued at US$ 4.93 billion in 2023, and it is expected to reach US$ 13.86 billion by 2031, with a CAGR of 13.8% during the forecast period of 2024-2031.

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Nucleic acid therapeutics represent a rapidly evolving segment of modern medicine, utilizing therapeutic DNA and RNA molecules to prevent, treat, and manage a broad range of diseases. The market is poised for substantial growth, driven by intensified research and development initiatives aimed at strengthening global healthcare capabilities amid rising incidences of chronic diseases and genetic disorders. Advances in biological therapeutics and DNA-based interventions, coupled with increasing demand for innovative pharmaceutical solutions and enhanced healthcare services, are further supporting market expansion.

Despite the promising outlook, the sector faces notable challenges. High treatment costs, a limited workforce skilled in molecular biology and gene-editing technologies, and inadequate infrastructure in certain regions continue to constrain market penetration. Nevertheless, the growing emphasis on personalized medicine-tailoring therapeutic strategies to individual genetic profiles-is fostering wider adoption of nucleic acid-based therapies. Additionally, increased investment by leading pharmaceutical and biotechnology companies in RNA- and DNA-based drug development, along with accelerated clinical implementation and rising global healthcare demands, is expected to sustain market growth and drive long-term commercialization of nucleic acid therapeutics.

List of Prominent Players in the Nucleic Acid Therapeutics Market:
• Novartis
• Moderna Inc
• BioNTech
• Arrowhead Pharmaceuticals
• Merck
• Thermo Fischer Scientific
• Sanofi
• Alnylam Pharmaceuticals
• Sarepta Therapeutics
• Qiagen
• Imugene
• Copernicus Therapeutics Inc.
• Protagonist Therapeutics
• Arbutus Biopharma
• Agilent Technologies
• Silence Therapeutics (UK),
• Astellas Pharma Inc. (Japan),
• CureVac SE (Germany),
• Sirnaomics (US),
• Arcturus Therapeutics Inc. (US)
• Other Market Players

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Market Dynamics
Drivers:
The global nucleic acid therapeutics market is experiencing strong growth, primarily driven by the increasing prevalence of genetic disorders-including cystic fibrosis, muscular dystrophy, and various cancers-that pose significant treatment challenges. Substantial investments from pharmaceutical companies, governmental agencies, and academic research institutions are accelerating drug discovery and development within this sector.

In addition, supportive government policies aimed at promoting pharmaceutical innovation have streamlined regulatory processes and fostered a favorable business environment for market participants. Collectively, these factors are reinforcing the expansion of the nucleic acid therapeutics market and are expected to sustain growth in the foreseeable future.

Challenges:
Despite its promising prospects, the nucleic acid therapeutics market faces several constraints. High research, development, and manufacturing costs limit patient accessibility and affordability. The complex nature of nucleic acid-based therapies presents technological challenges related to delivery systems, molecular stability, and large-scale production. Moreover, stringent regulatory requirements and extended approval timelines can delay market entry for new products. Limited awareness and understanding of these therapies among healthcare professionals and patients further impede adoption, presenting ongoing barriers to broader market penetration.

Regional Trends:
North America is projected to maintain a leading position in the nucleic acid therapeutics market, supported by a robust compound annual growth rate (CAGR) over the forecast period. This dominance is driven by the high prevalence of chronic diseases such as cancer and diabetes, growing demand for targeted and personalized treatment options, and substantial governmental funding for advanced medical research. Europe also represents a significant regional market, underpinned by increased R&D investments that advance gene therapy applications and address rising healthcare demands. Additionally, factors such as higher disposable incomes, expanding population bases, and continuous improvements in healthcare infrastructure are expected to further reinforce market growth across both regions.

Recent Developments:
• In April 2024, Arrowhead Pharmaceuticals, Inc. announced the dosing of its investigational RNA interference (RNAi) therapeutic, ARO-CFB, in a Phase 1/2a clinical trial. The trial included up to sixty-six healthy volunteers and patients with complement-mediated kidney disease.
• In Aug 2022, Merck and Orna Therapeutics entered into a collaboration agreement to jointly explore, create, and market various initiatives, such as vaccines and treatments, in the fields of infectious disease and oncology.

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Segmentation of Nucleic Acid Therapeutics Market-
By Technology-
• RNA Targeted Therapeutics
• Gene Therapies
• Epigenetic and microRNA Modulating Therapies
• Genome Editing Therapies
• Others
By Application-
• Autoimmune Disorders
• Genetic Disorders
• Infectious Diseases
• Cancer
• Others
By End-User-
• Hospitals & Clinics
• Academic & Research Institutes
• Others
By Region-
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa

Read Overview Report- https://www.insightaceanalytic.com/report/nucleic-acid-therapeutics-market/2548

About Us:
InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.

Contact us:
InsightAce Analytic Pvt. Ltd.
Visit: https://www.insightaceanalytic.com/
Tel : +1 607 400-7072
Asia: +91 79 72967118
info@insightaceanalytic.com

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