RNA - based Therapeutics and Vaccines Market to Garner Brimming Revenues by 2024

RNA plays a significant role in many biological processes thus it is considered to be a major target to develop advanced therapeutics and chemical genetic probe. In protein synthesis, RNA is a center figure that catalyzes reactions, encodes proteins, regulates gene expressions and plays another essential role in biological processes.


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RNA-based therapeutics and vaccines are a new class of treatment and precaution measure for a several rare and chronic diseases such as tuberculosis, cancer, diabetes, and cardiovascular condition. Ongoing research and development activities for the development of advanced biological drugs have widened the scope of therapeutic targets for a verity of diseases. This includes numerous RNA-based therapeutics under clinical trials for conditions such as genetic diseases and infectious diseases such as HIV-AIDS, as RNA controls human gene expression.

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RNA-based therapeutics is mainly classified by its activity mechanism, and include inhibitors of mRNA translation (antisense), catalytically active RNA molecules (ribozymes), the agents of RNA interference (RNAi), and RNAs that bind protein and other molecular ligands (aptamers). RNAi was discovered in 1990 and termed post-transcriptional gene silencing as it works by turning off or silencing gene expression. Currently here are around 700 nucleic acid-based (DNA and RNA) therapeutics in the pipeline and around 60% of that are in preclinical development.

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Among these, 60% of pipeline products, 30% therapeutics are for the treatment of oncology. This technology has appeared to be dominant in the RNA-based therapeutics and vaccines market. Other technology such as RNA antisense, involves RNA strand synthesis, which binds to a specific mRNA in order to prevent translation. However, the issue of toxicity and drug delivery associated with RNA-based therapies is a significant challenge for commercialization. However, several new technologies have emerged to overcome these challenges, which will lead to the promising future of RNA-based therapeutics.

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