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Personalised tumor vaccines keep cancer in check

08-21-2017 02:12 PM CET | Health & Medicine

Press release from: SMi Group

Throughout the last decade, novel cancer therapeutics has seen tremendous developments, through targeting tumor cell-intrinsic pathways, as well as targeting tumor cell-extrinsic factors such as growth factors.

Notable clinical success of checkpoint inhibitors as well as adoptively transferred genetically engineered T cells further demonstrates the critical role of T-cells in cancer control and rejection. However, many patients still do not respond to checkpoint inhibitor therapies. This creates the need for effective means of expanding the T-cells in patients using cancer vaccines, which will be further explored by MSD, Exicure, Genentech and INSERM.

There has been substantial progress made in these fields and It's time to connect these fields to enable the linking of genetic alterations with the type of immune response. SMi's 6th annual Cancer Vaccines conference will host high level cancer geneticists, cancer biologists, experts in cancer antigen, tumor immunologists and vaccinologists, to discuss the immunological basis for therapeutic cancer vaccines and how the current understanding of cancer genomics, antigens and T-cell biology might enable development of next-generation novel therapies for patients with cancer.

With the increasing use of various immunotherapy strategies in the clinic, it is essential for immunomonitoring techniques to be conducted to follow the response of patients to therapy. Such investigations will enable the discovery of neoantigens that may contribute to the efficacy of treatment. The potential cellular players, the use of screening techniques to monitor effects of treatment and an account of an immunotherapy trial will illustrate what is possible in clinical practice.

Running alongside the conference will an exclusive pre-conference workshop held on Tuesday 26th September 2017.

The Biomarkers of immune response workshop is aimed at both clinical and research investigators to give insights into how to develop tools for both developing new therapeutic strategies and how to monitor responses to treatment. This will enable you to design clinical trials and to set up laboratory investigations to evaluate response to immunotherapy.

Workshop hosts:

Rose-Ann Padua, Research Director, INSERM
Antoine Toubert, Head, Alloimmunity, Autoimmunity, Transplantation, INSERM
Eric Tartour, Head, Laboratory of Clinical Immunology, Hopital Europeen George Pompidou
Sharam Kordasti, Senior Lecturer, Kings College London
Zwi Berneman, Professor of Haematology, University of Antwerp

Cancer Vaccines 2017 is proudly sponsored by Northwest Biotherapeutics

6th annual Cancer Vaccines
27th – 28th September 2017
London, UK
Contact e-mail:
Contact tel: +44 (0) 207 827 6012

About SMi Group:
Established since 1993, the SMi Group is a global event-production company that specializes in Business-to-Business Conferences, Workshops, Masterclasses and online Communities. We create and deliver events in the Defence, Security, Energy, Utilities, Finance and Pharmaceutical industries. We pride ourselves on having access to the world’s most forward thinking opinion leaders and visionaries, allowing us to bring our communities together to Learn, Engage, Share and Network. More information can be found at

Kyra Williams
SMi Group
1 Westminster Bridge Road

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