Global 3D Cell Culture Market Forecast 2017-2021

Cell based assays have been an indispensable tool for an array of basic and advanced in vitro biotechnology research. Currently large percentages of researchers globally are dependent of two dimensional (2D) cell cultures, however it is well known that 2D and 3D cell cultures differ greatly in their functional and biochemical characteristics. This is especially important in tissue engineering and clinical research where in vivo behavior is to be studied. 3D cell culture market is driven by the fact that these cell culture systems have greatly reduced the need of animal models in certain clinical experiments, as these systems closely resemble in vivo environment that is essential for drug discovery and associated studies. Increasing preclinical research for discovery of novel drugs in neurology, cardiology, oncology, infection and others has further supported the 3D cell culture market growth.

One of the important factors in consideration in 3D cell culture is mimicking the extracellular matrix that provides physical structure, and secretes growth factors for supporting cellular growth and communication. Hence choosing 3D cell culture type plays a key role in success of research. Types of 3D cell cultures include scaffold-free systems, scaffolds, gels, bioreactors, and microchips. Use of 3D cell culture is rapidly increasing across all applications. Currently oncology and stem cell research are prominent applications driving the overall 3D cell culture market globally. Gradual shift from 2D cell cultures to 3D cell cultures is happening in majority of the biotechnology research laboratories. However, 3D cell culture would not completely replace 2D cell culture systems, as 2D systems are more advantageous in microscopy studies.

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Currently, countries in the North America and Europe region lead the 3D cell culture market. Higher number of research laboratories, government and private investor support for novel drug discovery, and trend for quick adoption of new technology are some of the basic factors driving the market growth in the regions. Increasing stem cell research in the South-East Asian countries including South Korea, Thailand, Singapore and others drives 3D cell culture market in Asia Pacific region. This region is expected to witness fastest growth during the forecast period.

3D cell culture market is comprised of large number of global players offering range of 3D cell culture systems compatible for specific research. Companies are trying to build expertise for development of newer technologies that are tailored for specific research activities conducted by research institutes and pharmaceutical companies. In 2014, Reprocell, a Japanese company acquired Reinnervate Ltd (UK) and Human Tissue supplier BioServe (USA). With this acquisition, the parent company plans to fuse its induced pluripotent stem cell technology with the 3D cell culture expertise for drug toxicity testing, neuroscience and cancer research. Key players in the market include Corning Incorporated, Sigma-Aldrich Co. LLC., Lonza, BioTek Instruments, Inc., Cosmo Bio, InSphero AG? and various others.

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