Track Clarithromycin Price Chart Historical and Forecast

Executive Summary

The global Clarithromycin price trend in 2025 reflected a year shaped by supply chain disruptions, tariff adjustments, freight volatility, seasonal demand shifts, and evolving procurement strategies across key pharmaceutical markets. Across North America, APAC, and Europe, price movements oscillated between temporary supply tightness and oversupply corrections, creating a dynamic pricing environment.

In Q1 2025, prices strengthened globally amid logistical bottlenecks, Lunar New Year disruptions, and strategic restocking. Q2 witnessed freight-driven spikes followed by sharp corrections due to oversupply from Asian producers. Q3 prices softened in most regions under inventory pressure and cautious buying behavior. By Q4 2025, the Clarithromycin Price Index recovered modestly across all regions as winter respiratory demand, restocking, and improved trade flows tightened supply.

Regional variations were evident. Germany and the United States recorded stronger Q4 rebounds exceeding 3 percent quarter-over-quarter, while China posted marginal gains reflecting balanced export conditions. Production cost trends remained relatively stable in late 2025 due to steady erythromycin feedstock and glucose input pricing, though compliance, insurance, and logistics expenses created localized upward pressure.

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Introduction

Clarithromycin remains a critical macrolide antibiotic used widely in respiratory infections, Helicobacter pylori treatment regimens, and combination therapies across hospital and outpatient settings. Given its heavy reliance on Asian active pharmaceutical ingredient production hubs, particularly China and India, the global Clarithromycin market remains highly sensitive to logistics, trade policies, freight costs, and seasonal demand cycles.

The 2025 market cycle demonstrated how interconnected production, tariffs, freight volatility, and procurement strategies influence price formation across continents. Import dependency in North America and Europe further amplified the impact of Asian supply shifts.

This report presents a detailed review of quarterly price movements through 2025, regional pricing patterns, cost structure trends, procurement behavior, and a forward-looking forecast.

Global Clarithromycin Price Overview

Global pricing in 2025 can be summarized in four distinct phases.

First Quarter 2025
Prices moved upward across all major markets due to shipping congestion, freight rate increases, Lunar New Year production slowdowns, and strong export demand. Supply-side constraints tightened availability, particularly in China and the United States.

Second Quarter 2025
Freight disruptions, peak season surcharges, and tariff-related procurement acceleration drove price spikes in April and May. However, oversupply from expanded Chinese and Indian production triggered price corrections in June.

Third Quarter 2025
Inventory abundance and cautious procurement weighed on pricing. Oversupply in Asia and Europe forced exporters to offer competitive discounts. North America experienced marginal declines amid tariff uncertainty and elevated inventories.

Fourth Quarter 2025
Prices rebounded modestly across all regions. Winter respiratory demand, restocking activity, reduced spot cargo availability, and improved logistics supported upward momentum.

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Quarterly Price Summary Table

The following table summarizes average quarterly prices and price index movements during 2025.

Quarter Ending Region Avg Price (USD/MT) Basis QoQ Change

March 2025 USA Not Disclosed CFR Upward Trend

March 2025 China Not Disclosed FOB Upward Trend

March 2025 Germany Not Disclosed CIF/CFR Upward Trend

June 2025 USA Not Disclosed CFR +0.38% (Apr-May), -1.17% (June)

June 2025 China Not Disclosed FOB +1.87%, +0.44%, -1.20%

June 2025 Germany Not Disclosed CIF/CFR +1.87%, +0.44%, -1.19%


September 2025 USA 205,826.67 CFR Los Angeles -0.33%

September 2025 China 205,730.00 FOB China -0.31%

September 2025 Germany 205,833.33 Reported Shipments -0.31%

December 2025 USA 212,205.00 CFR +3.10%

December 2025 China 189,911.67 FOB Shanghai +0.08%

December 2025 Germany 212,185.00 CFR Hamburg +3.09%

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Regional Analysis

North America

The United States market remained heavily import-dependent throughout 2025. Q1 prices strengthened due to port congestion at Los Angeles and Savannah, rising freight rates, and strategic stockpiling.

In Q2, severe global freight disruptions caused a sharp spike in May. A 10 percent baseline tariff on Chinese goods increased landed costs. However, June saw a correction as oversupply from China and India combined with cautious buyer activity.

Q3 recorded a 0.33 percent quarter-over-quarter decline. Elevated inventories and tariff uncertainty suppressed spot activity, though steady hospital demand limited deeper price erosion.

By Q4 2025, the Clarithromycin Price Index rose 3.10 percent quarter-over-quarter to USD 212,205.00 per metric ton. Proactive restocking ahead of winter respiratory season tightened spot cargo availability. Lower China-to-USA freight partially offset higher insurance and inspection expenses, resulting in moderate upward momentum rather than sharp spikes.

Demand Outlook
Seasonally stronger prescription-driven demand supported Q4 recovery. However, antimicrobial stewardship practices and therapeutic substitution limited explosive growth.

Cost Trends
Erythromycin feedstock pricing remained stable, but compliance costs and inspection requirements increased operational expenses.

Procurement Behavior
Buyers increasingly adopted staggered procurement strategies to mitigate tariff volatility and freight swings.

Asia Pacific

China continued to dominate global API production. Q1 saw rising prices driven by export demand, Lunar New Year closures, and freight disruptions.

Q2 recorded modest increases in April and May before a June correction due to excess capacity and aggressive competition. Chinese pharmaceutical deflation and price wars pressured margins.

In Q3, the Clarithromycin Price Index fell 0.31 percent quarter-over-quarter. Elevated inventories and weak domestic pharmaceutical demand suppressed pricing power despite temporary plant maintenance and port congestion.

Q4 2025 showed a marginal 0.08 percent increase. The average price stood at USD 189,911.67 per metric ton FOB Shanghai. Localized flooding and solvent-recovery unit maintenance reduced intermediate output. Export-grade volumes tightened slightly, but balanced production prevented strong upward pressure.

Demand Outlook
Hospital tenders and overseas procurement from India and Brazil supported export activity. Domestic demand remained moderate.

Cost Structure
Corn-derived glucose and energy inputs remained broadly stable. Logistics and airfreight premiums briefly elevated FOB offers.

Supply Conditions
Inventory levels at coastal warehouses remained normal, preventing acute shortages.

Europe

Germany served as the benchmark European market. Q1 2025 prices rose steadily amid port congestion at Hamburg and labor strikes across Northern Europe.

Q2 saw April and May firming due to logistics bottlenecks and low Rhine water levels. However, June experienced downward correction as diverted Chinese shipments increased inventory availability.

Q3 prices declined 0.31 percent quarter-over-quarter to USD 205,833.33 per metric ton. Abundant inventories and subdued seasonal demand reduced procurement urgency.

In Q4, the Clarithromycin Price Index rose 3.09 percent to USD 212,185.00 per metric ton CFR Hamburg. Tighter imports, precautionary recalls, and winter respiratory demand supported restocking. Stable origin production and unchanged freight limited cost pass-through, resulting in moderate gains.

Demand Outlook
Winter respiratory infections and routine tendering underpinned steady offtake.

Logistics and Trade Flow
Asian maintenance cycles temporarily tightened import flows. However, stable freight prevented volatility.

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Historical Quarterly Review

The 2025 price cycle highlights three major forces shaping the Clarithromycin market.

First, freight and logistics disruptions significantly influenced price spikes in Q1 and Q2.
Second, oversupply and aggressive exporter pricing created mid-year corrections.
Third, seasonal healthcare demand and inventory rebuilding drove Q4 stabilization.

Trade flow shifts, particularly U.S. tariff adjustments and redirected Chinese shipments, altered global supply allocation throughout the year.

Production and Cost Structure Insights

Clarithromycin production relies heavily on fermentation processes using erythromycin intermediates. Key cost components include:

Erythromycin feedstock
Corn-derived glucose inputs
Energy and utilities
Solvent recovery operations
Compliance and inspection costs
Freight and insurance
In 2025, feedstock costs remained relatively stable. Energy inputs showed limited volatility in Q4. Compliance expenses and freight premiums contributed to regional cost variations.

Chinese overcapacity in mid-2025 compressed producer margins, leading to competitive discounting. By late 2025, supply discipline improved, supporting modest price recovery.

Procurement Outlook

The Clarithromycin Price Forecast suggests moderate firmness in early 2026. Drivers include:

Seasonal respiratory demand
Inventory normalization
Stable freight markets
Controlled production output
However, risks remain tied to:

Trade policy shifts
Freight disruptions
Overcapacity resurgence in China
Buyers are expected to maintain flexible sourcing strategies, diversify suppliers, and avoid excessive forward inventory accumulation.

Frequently Asked Questions

Why did Clarithromycin prices rise in Q4 2025

Winter respiratory demand, proactive restocking, tighter import flows, and moderate logistics pressure supported quarter-over-quarter increases in North America and Europe.

Why did prices decline in Q3 2025

Global oversupply, high inventories, cautious procurement behavior, and subdued seasonal demand created downward pressure across regions.

How do freight costs impact Clarithromycin pricing

As a heavily traded API, Clarithromycin pricing is sensitive to ocean freight, port congestion, and insurance costs. Freight spikes in Q2 2025 caused significant short-term price increases.

What are the major production cost drivers

Erythromycin feedstock, glucose inputs, utilities, compliance costs, and logistics represent the largest cost components.

What is the outlook for 2026

Moderate price stability with slight upward bias is expected, supported by balanced supply-demand conditions and controlled production growth.

How ChemAnalyst Supports Market Participants

ChemAnalyst delivers real-time price tracking, weekly market updates, and forward-looking forecasts for more than 450 commodities, including pharmaceutical APIs such as Clarithromycin.

The platform provides:

Real-time price indices
Regional supply-demand analysis
Plant shutdown monitoring
Trade-flow intelligence
Freight and logistics tracking
Procurement timing insights
With analyst teams based in Houston, Cologne, and New Delhi, and coverage across major global ports including Shanghai, Rotterdam, Hamburg, Busan, and Houston, ChemAnalyst ensures accurate and timely reporting.

Buyers benefit from structured forecasts that support cost optimization and supply chain resilience. By understanding not just price movements but the drivers behind them, procurement teams can strategically plan sourcing, manage inventory risk, and navigate volatility with confidence.

Clarithromycin prices in 2025 illustrated the delicate balance between supply chain disruptions, global trade flows, and seasonal healthcare demand. As the market transitions into 2026, disciplined production, cautious procurement, and real-time intelligence will remain central to managing price risk effectively.

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