Global Biotechnology Market Size, Share, Forecast & Technology Analysis Report 2025-2033

The global biotechnology market size was valued at USD 761.5 Billion in 2024 and is projected to reach USD 1,315.9 Billion by 2033. The market is expected to grow at a CAGR of 6.27% between 2025 and 2033. Key growth drivers include advancements in genetic engineering, increasing demand for personalized medicine, and sustainable agricultural solutions.

Study Assumption Years

Base Year: 2024
Historical Years: 2019-2024
Forecast Period: 2025-2033

Biotechnology Market Key Takeaways

The global biotechnology market size reached USD 761.5 Billion in 2024.
The market is expected to grow at a CAGR of 6.27% during 2025-2033.
The forecast period for the market is from 2025 to 2033.
Rapid advancements in genetic engineering, such as CRISPR-Cas9, drive innovation across medicine, agriculture, and industrial processes.
Increasing demand for personalized medicine based on genomic sequencing propels production of biopharmaceuticals and targeted therapies.
Sustainable agriculture solutions including genetically modified crops and biopesticides are boosting biotechnology adoption.
Integration of bioinformatics enhances R&D capabilities and biotechnological efficiencies.

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Market Growth Factors

The biotechnology market growth is propelled by rapid innovation in gene editing techniques, including CRISPR-Cas9 technology that allows precise modification of genes within organisms. This innovation has transformative potential in medicine with novel gene therapies for genetic disorders and cancers, agriculture with genetically engineered crops, and industrial manufacturing of pharmaceuticals and enzymes.

Increasing demand for personalized medicine driven by advancements in genomic sequencing technologies has led to targeted therapies that enhance efficacy and reduce side effects. Biotechnology plays a central role in developing biopharmaceuticals such as monoclonal antibodies and gene therapies. Additionally, diagnostics based on genetic markers enable early disease detection and prognosis, shifting healthcare toward precision medicine.

Sustainability challenges in agriculture due to rising food demand and environmental concerns fuel the need for biotechnological solutions. Genetically modified organisms engineered for higher yields, pest resistance, and improved nutrition, along with biopesticides from natural sources, reduce environmental impacts. Biotechnology optimizes plant traits for climate resilience and nutrient use efficiency, supporting food security and resource sustainability.

Market Segmentation

By Product Type:

Instruments: Fundamental tools for precise analysis and experimentation supporting advanced research and diagnostics.
Reagents: Essential components fueling experimental processes to enable accurate results and breakthroughs.
Software and Services: Software provides data analysis, visualization, and integration solutions; services include consulting, training, and technical support to facilitate biotechnology adoption and innovation.

By Technology:

Nanobiotechnology: Combines nanoscale materials with biological systems, enabling breakthroughs in drug delivery, diagnostics, and therapies.
Tissue Engineering and Regeneration: Develops functional tissues to address organ shortages and medical needs.
DNA Sequencing: Provides comprehensive genomic analysis critical for personalized medicine and disease understanding.
Cell-Based Assays: Offers insights into cellular behavior for drug development and toxicity testing.
Fermentation: Central bioprocessing method producing biofuels, pharmaceuticals, and enzymes.
PCR Technology: Amplifies DNA, foundational to diagnostics and genetic research.
Chromatography: Separates biomolecules with precision, vital for drug purification and analytical processes.
Others

By Application:

Healthcare: The largest segment, driving biotechnology innovations in diagnostics, treatment development, and personalized medicine.
Food and Agriculture: Employs biotechnology for crop improvement and sustainable farming.
Natural Resources and Environment
Industrial Processing
Bioinformatics
Others

Regional Insights

North America dominates the biotechnology market, attributed to its strong R&D investments, well-established regulatory frameworks, and robust innovation ecosystem. The region benefits from leading universities, biotech companies, and venture capital emphasis that accelerates commercial biotech solutions. The U.S. hosted the NSCEB 'Biotech Across America' roadshow in 2025, highlighting North Carolina's biopharma manufacturing, workforce, and agricultural biotech advances, underscoring the sector's critical role in economic resilience and supply chain onshoring.

Recent Developments & News

In May 2025, Biogen and City Therapeutics partnered to develop RNA interference (RNAi) therapies for central nervous system diseases, combining City Therapeutics' RNAi platform with Biogen's delivery technology.
In May 2025, Biocon Biologics, via partner Yoshindo Inc., launched Ustekinumab BS Subcutaneous Injection [YD] in Japan, a biosimilar for psoriasis vulgaris and psoriatic arthritis treatment.
In April 2025, Novartis announced a USD 23 Billion investment over five years to expand its U.S. biotech and pharmaceutical presence, including seven new facilities and increased workforce.
In April 2025, Amgen invested USD 900 Million additional for expanding its Ohio biologics manufacturing site, totaling over USD 1.4 Billion spent and 750 jobs expected.
In March 2025, Roche opened the Roche Genentech Innovation Center Boston at Harvard, focusing on cardiovascular, renal, and metabolism R&D and AI-driven drug discovery.

Key Players

Amgen Inc.
Biocon Limited
Biogen Inc.
F. Hoffmann-La Roche AG
Genmab A/S
Lonza Group AG
Novartis AG
Novo Nordisk A/S
Pfizer Inc.
Regeneron Pharmaceuticals Inc.
Seagen Inc.
Syngenta AG
Vertex Pharmaceuticals Incorporated

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