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United States Weight Loss Therapeutics Market to Grow at 20.6% CAGR through 2033, Driven by Surging Demand for GLP-1 Agonists and Next-Gen Prescription Drugs | DataM Intelligence
According to DataM Intelligence, the global Weight Loss Therapeutics market size reached US$ 3.92 billion in 2024 and is expected to reach US$ 20.84 billion by 2033, growing at a CAGR of 20.6% during the forecast period 2025-2033. This growth is propelled by the escalating global obesity and overweight epidemic, rapid adoption of highly effective GLP-1 receptor agonists and dual GIP/GLP-1 therapies, increasing prescription of semaglutide and tirzepatide-based drugs, expanding access through retail and online pharmacies, rising consumer awareness of weight management, and strong pipeline advancements in novel oral and injectable formulations.Get a Free Sample PDF Of This Report (Get Higher Priority for Corporate Email ID): https://www.datamintelligence.com/download-sample/weight-loss-therapeutics-market?jd
United States Key Industry Developments
☑️ January 2026: Novo Nordisk expanded manufacturing capacity for Wegovy (semaglutide), addressing supply constraints and securing additional formulary placements across major U.S. payers amid surging demand.
☑️ January 2026: Eli Lilly reported accelerated uptake of Zepbound (tirzepatide), with new real-world evidence demonstrating superior weight loss outcomes in obese patients with comorbidities.
☑️ December 2025: Rhythm Pharmaceuticals advanced its setmelanotide program for rare genetic obesity, gaining traction in pediatric and specialty clinics following expanded FDA approvals.
☑️ December 2025: Currax Pharmaceuticals strengthened distribution partnerships for Contrave, targeting retail pharmacy channels to reach broader overweight populations.
Japan Key Industry Developments
☑️ January 2026: Japanese regulatory authorities fast-tracked reviews for GLP-1-based therapies, with Novo Nordisk and Eli Lilly preparing launches of semaglutide and tirzepatide injections for obesity management.
☑️ January 2026: Local healthcare providers showcased integrated weight loss programs incorporating prescription drugs and natural supplements at major endocrinology conferences in Tokyo.
☑️ December 2025: Growing adoption of oral anti-obesity medications and injectables in urban clinics, driven by increasing obesity rates and government focus on metabolic health.
Key Mergers and Acquisitions
✦ Eli Lilly announced a strategic collaboration and potential acquisition discussions in the GLP-1 space to further strengthen its oral and dual-agonist pipeline for weight loss (January 2026).
✦ Novo Nordisk continued expansion through targeted bolt-on acquisitions of delivery technology firms to enhance next-generation injectable and oral formulations for obesity therapeutics.
✦ GSK secured a licensing agreement with a biotech innovator to advance novel oral anti-obesity candidates, positioning for entry into the high-growth prescription segment in early 2026.
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Market Segmentation Analysis
By Therapeutics: Prescription Drugs dominate (valued at US$ 1.79 billion in 2024); followed by Over-the-Counter, Natural Supplements, and Others.
By Condition: Obesity holds the largest share; followed by Overweight and Others.
By Dosage Form: Injectables lead due to GLP-1 efficacy; followed by Tablets, Capsules, and Others.
By Distribution Channel: Retail Pharmacies and Online Pharmacies grow rapidly; Hospital Pharmacies remain key for specialty prescriptions.
Regional Insights
North America commands the largest market share in the global Weight Loss Therapeutics market, valued at US$ 1.54 billion in 2024, supported by high obesity rates, widespread adoption of GLP-1 agonists like semaglutide and tirzepatide, favorable reimbursement policies, strong clinical evidence, and the presence of leading innovators driving prescription volume and patient access. Asia-Pacific remains the fastest-growing region, fueled by rapidly rising obesity prevalence in emerging economies, increasing healthcare spending, expanding availability of branded and generic anti-obesity drugs, growing online pharmacy penetration, and aggressive market entry by global players.
Growth Drivers
✦ Explosive global rise in obesity and overweight populations
✦ Breakthrough efficacy of GLP-1 and dual GIP/GLP-1 receptor agonists
✦ Rapid prescription growth and supply chain improvements for semaglutide and tirzepatide
✦ Increasing consumer demand for convenient oral and injectable options
✦ Pipeline innovation, regulatory approvals, and expanding distribution channels
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Key Players
The market includes leading companies such as Novo Nordisk A/S, Currax Pharmaceuticals LLC, Eli Lilly and Company, VIVUS LLC, Rhythm Pharmaceuticals, Inc., CHEPLAPHARM GmbH, GSK plc, KVK Tech, Inc., Teva Pharmaceutical Industries Ltd, and others.
Key Highlights (Top 5 Key Players)
✦ Novo Nordisk A/S - Leading with Wegovy and Ozempic dominance in the GLP-1 category.
✦ Eli Lilly and Company - Driving growth through Zepbound and Mounjaro's superior dual-agonist efficacy.
✦ Rhythm Pharmaceuticals, Inc. - Specializing in rare genetic obesity treatments with setmelanotide.
✦ GSK plc - Advancing oral anti-obesity candidates and broad portfolio expansion.
✦ Currax Pharmaceuticals LLC - Strong in Contrave for comprehensive weight management.
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