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NASH Drugs Market to Reach USD 38.26 Billion by 2034 Driven by Rising Liver Disease Burden & Breakthrough Therapeutic Pipelines

12-05-2025 11:26 AM CET | Business, Economy, Finances, Banking & Insurance

Press release from: Exactitude Consultancy

NASH Drugs Market

NASH Drugs Market

Pune, India - December 2025 - The global NASH (Non-Alcoholic Steatohepatitis) Drugs Market, valued at USD 5.94 billion in 2024, is projected to reach USD 38.26 billion by 2034, expanding at an exceptional 20.6% CAGR (2025-2034), according to Exactitude Consultancy. Rising obesity rates, diabetes prevalence, metabolic syndrome, and the absence of FDA-approved therapies until recently are accelerating investment in NASH drug development.

Market Summary
The NASH Drugs Market is witnessing explosive growth as pharmaceutical companies race to commercialize treatments targeting fibrosis, inflammation, and metabolic dysfunction. NASH affects millions globally and is emerging as a leading cause of liver transplantation. Breakthrough therapeutic classes-including FXR agonists, FGF21 analogs, PPAR agonists, THR-β agonists, CCR2/CCR5 inhibitors, GLP-1 combinations, and anti-fibrotic agents-are advancing rapidly through late-stage pipelines. Improved diagnostic tools such as non-invasive imaging, biomarkers, and AI-based fibrosis assessment are facilitating earlier intervention. North America leads the market due to high disease prevalence, while Asia-Pacific is the fastest-growing region driven by rising metabolic disorders.

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Key Takeaways
• 2024 Market Size: USD 5.94 Billion
• 2034 Forecast: USD 38.26 Billion
• CAGR: 20.6% (2025-2034)
• FXR agonists and combination therapies dominating late-stage development
• High unmet clinical need boosting R&D investment
• Asia-Pacific experiencing sharp growth due to increasing obesity and diabetes

Market Drivers
• Growing global burden of NAFLD and NASH
• Increased funding for fibrosis and metabolic disease research
• Pipeline progression of first-in-class and combination therapies
• Advances in non-invasive diagnostics enabling patient identification
• Rising partnership activity between biotech firms and large pharma

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Segmentation Snapshot
By Drug Class
• FXR Agonists
• PPAR Agonists
• THR-β Agonists
• FGF21 Analogs
• GLP-1 Combinations
• CCR2/CCR5 Inhibitors
• Others

By Stage of Treatment
• Early-Stage NASH
• Advanced Fibrosis
• Cirrhotic NASH

By Distribution Channel
• Hospital Pharmacies
• Specialty Clinics
• Retail & Online Pharmacies

By Region
• North America (Largest Market)
• Europe
• Asia-Pacific (Fastest Growing)
• Latin America
• Middle East & Africa

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Recent Developments
• FXR agonists achieving key regulatory milestones.
• Combination regimens (e.g., GLP-1 + FGF21) showing superior fibrosis reduction.
• AI-based diagnostic tools improving staging accuracy for NASH clinical trials.

Expert Quote - Irfan Tamboli, Business Development Executive
"NASH represents one of the highest unmet needs in metabolic disease. Breakthrough drug classes and combination therapies are finally bringing hope to millions of patients worldwide."

Conclusion
The NASH Drugs Market is on a steep growth trajectory through 2034 as innovative metabolic and anti-fibrotic therapies progress toward commercialization. Companies with strong pipelines, biomarker-driven strategies, and combination platforms will dominate this rapidly evolving market.

This report is also available in the following languages : Japanese (NASH治療薬市場), Korean (NASH 약물 시장), Chinese (NASH药物市场), French (Marché des médicaments contre la NASH), German (Markt für NASH-Medikamente), and Italian (Mercato dei farmaci per la NASH), etc.

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Connect Us:
Irfan Tamboli
PHONE NUMBER +1 (704) 266-3234
EMAIL ADDRESS: sales@exactitudeconsultancy.com

About Us
Exactitude Consultancy is a market research & consulting services firm which helps its client to address their most pressing strategic and business challenges. Our market research helps clients to address critical business challenges and also helps make optimized business decisions with our fact-based research insights, market intelligence, and accurate data.

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