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Top Market Shifts Transforming the Central Nervous System Biomarkers Market Landscape: Key Insights

11-14-2025 07:19 AM CET | Health & Medicine

Press release from: The Business Research Company

Central Nervous System Biomarkers Market

Central Nervous System Biomarkers Market

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What Is the Expected CAGR for the Central Nervous System Biomarkers Market Through 2025?
The valuation of the central nervous system biomarkers market has demonstrated robust expansion lately, projected to ascend from a figure of $5.58 billion in the year 2024 to reach $6.14 billion by 2025, reflecting a consistent compound annual growth rate of 9.9%; this upward trajectory throughout the historical phase is largely fueled by escalating apprehensions surrounding neurological conditions, the widespread incidence of ailments affecting the central nervous system, an increased need for superior diagnostic and therapeutic methods, advancements in medical facilities, and the increasing proportion of elderly individuals within the population.

What's the Projected Size of the Global Central Nervous System Biomarkers Market by 2029?
Anticipation is high for vigorous expansion within the central nervous system biomarkers market over the upcoming years, projecting a valuation of $8.98 billion by 2029, driven by a consistent compound annual growth rate (CAGR) of 10.0%. This upswing through the projection horizon is fundamentally supported by several key factors: a rising incidence of neurological conditions, escalating requirements for tailored medical treatments, an expanding elderly demographic, heightened emphasis on identifying diseases sooner, and a greater need for diagnostic methods that do not involve invasive procedures. Furthermore, this period will be characterized by significant trends such as the introduction of novel technological breakthroughs, strategic alliances forming between biotech firms, pharmaceutical entities, and various other invested parties, increased investigation into biomarkers derived from cerebrospinal fluid and blood, alongside the implementation of artificial intelligence and machine learning techniques.

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Top Growth Drivers in the Central Nervous System Biomarkers Industry: What's Accelerating the Market?
Anticipated escalation in the prevalence of conditions impacting the nervous system is foreseen to stimulate expansion within the central nervous system biomarker sector in the future.Neurological disorders, encompassing diverse ailments impacting the brain, spinal cord, and peripheral nerves globally, stem from numerous etiologies such as heredity, pathogens, immune system dysfunction, deterioration, growths, circulatory problems, and physical trauma.Within the context of CNS ailments, biomarkers originating from the central nervous system prove invaluable for confirming diagnoses, estimating the likelihood or outcome of a condition, gauging the severity of the ailment, and monitoring how effectively interventions are working, thus being crucial in comprehending these pathologies and their treatability.To illustrate this growing burden, data from the US governmental organization, the Centers for Disease Control and Prevention, indicated in April 2023 that approximately 6.7 million individuals in the United States, aged 65 and above, were living with Alzheimer's disease, a figure projected to climb to 14 million by 2060, effectively almost tripling, with the prevalence of Alzheimer's doubling every five years subsequent to reaching age 65;consequently, the increasing incidence of neurological diseases underpins the market growth for CNS biomarkers.

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What Trends Will Shape the Central Nervous System Biomarkers Market Through 2029 and Beyond?
A significant movement within the central nervous system biomarker sector involves the rising prominence of novel therapeutic product authorizations. Leading entities competing in this arena are heavily invested in advancing groundbreaking pharmaceuticals and securing regulatory clearance to enhance their competitive standing. A prime illustration occurred in January 2022 when Denovo Biopharma LLC, a US-based biopharma firm currently in the clinical phase, successfully secured the U.S. Food and Drug Administration's (FDA) go-ahead to proceed with its Investigational New Drug (IND) application for liafensine (DB104), targeting treatment-resistant depression (TRD). This trial is notable as the inaugural worldwide CNS clinical study for TRD that employs a biomarker-driven approach; furthermore, its potential includes pinpointing individuals exhibiting a higher probability of favorable outcomes with liafensine, thus paving the way for more tailored therapeutic selections. Liafensine itself is a forthcoming agent designed to elevate the concentrations of both dopamine and norepinephrine within the brain.

What Are the Main Segments in the Central Nervous System Biomarkers Market?
The central nervous system biomarkersmarket covered in this report is segmented -

1) By Type: Safety Biomarker; Efficacy Biomarker; Validation Biomarker; Other Types
2) By Disease: Multiple Sclerosis; Alzheimer's Disease; Parkinson's Disease; Traumatic Brain Injury; Other Diseases
3) By Application: Drug Discovery And Development; Personalized Medicines; Disease Risk Assessment; Diagnostics; Other Applications
4) By End-Users: Diagnostic Labs; Clinics; Hospitals; Research Centers; Other End-Users

Subsegments:
1) By Safety Biomarker: Toxicity Biomarkers; Adverse Event Biomarkers
2) By Efficacy Biomarker: Pharmacodynamic Biomarkers; Response Biomarkers
3) By Validation Biomarker: Predictive Biomarkers; Prognostic Biomarkers
4) By Other Types: Diagnostic Biomarkers; Biomarkers For Disease Progression

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Which Top Companies are Driving Growth in the Central Nervous System Biomarkers Market?
Major companies operating in the central nervous system biomarkers market include F. Hoffmann-La Roche AG, Novartis AG, Siemens Healthineers, Thermo Fisher Scientific Inc, Abbott Laboratories, Merck KGaA, Eurofins Scientific, Charles River Laboratories International Inc., PerkinElmer Inc., Bio-Rad Laboratories Inc., QIAGEN N.V., Axon Neuroscience SE, Alector Inc., Oryzon Genomics S.A., Abastar Mdx Inc., Banyan Biomarkers Inc., Avacta Group PLC, Geno Technology Inc., Anavex Life Sciences Corp., Alseres Pharmaceuticals Inc., Aposense Ltd., Applied Neurosolutions Inc., C2N Diagnostics, Alzheon Inc., DiaGenic ASA, Abiant Inc., Avid Radiopharmaceuticals Inc., Acumen Pharmaceuticals Inc., Cassava Sciences Inc., Denali Therapeutics

Which Regions Will Dominate the Central Nervous System Biomarkers Market Through 2029?
North America was the largest region in the central nervous system biomarkers market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the central nervous system biomarkers market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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