Hormone Supplements Market to Reach USD 30,648 Million by 2031 Top 20 Company Globally

The hormone supplements category covering products such as melatonin sleep aids, DHEA formulations, testosterone boosters and thyroid support supplements sits at the intersection of supplements, preventive health and personalized wellness. Manufacturers in this space sell active hormonal ingredients (or botanicals/translational actives that claim hormone-modulating effects) through multiple formats (capsules, tablets,es, powders and liquid drops) into retail, e-commerce and clinical channels. Demand is driven by aging populations, rising health literacy, athlete and fitness markets, and consumer interest in sleep, metabolic health and anti-aging. Recent market research vendors and industry trackers have profiled this category as a fast-growing subsegment of the broader supplements market.

The global market size for hormone supplements in 2024 of USD 19,953 million with a projected CAGR of 6.2% to 2031 reaching market size USD 30,648 million by 2031. with an average selling price of USD 95,000 per ton, implies a shipped volume on the order of 210,031 ton sold in 2024. Factory gross margin is 28%, implying a factory gross profit of USD 26,600 per ton and a factory cost of goods sold of USD 68,400 per ton. A COGS breakdown is raw materials (active ingredients + excipients), packaging, direct labor, quality & regulatory, manufacturing overhead & energy, distribution & logistics, other (waste/testing). A single line full machine capacity production is around 800 ton per line per year. Downstream demand is concentrated in sports & fitness and male health, sleep & mental wellness, metabolic/weight management formulations, anti-aging/hormonal balance, thyroid support and other niche uses.
Latest Trends and Technological Developments
Regulatory scrutiny of melatonin products intensified in 2025 after quality and labeling investigations found significant variability in melatonin content in some over-the-counter products, prompting advisories and seizures in multiple markets; Australias Therapeutic Goods Administration public warnings and follow-up reporting appeared in mid-2025, highlighting safety concerns for children in particular (news coverage JuneJuly 2025). This trend is driving buyers and platforms to demand third-party testing and tighter supply-chain traceability.
Brands are also capitalizing on hormone-adjacent consumer interest products marketed to modulate GLP-1, or to support appetite/metabolic control, have proliferated since 2024; celebrity and influencer product launches in late 2024 and 2025 leverage this trend (for example, consumer press coverage of new GLP-1-targeting supplements in 2024). This fuels both interest and regulatory attention because these products border pharmaceutical modalities and can attract scrutiny for therapeutic claims.
Technology and formulation developments include higher-purity synthetic actives, microencapsulation for controlled release (improving stability and taste in gummy formats), growth in clinically validated ingredient blends, expanded use of contract-manufacturing organizations (CMOs) with in-house analytics, and more rapid adoption of direct-to-consumer (DTC) telehealth + supplement bundles. Industry trend reports in late 2024 to 2025 note rising investment in personalization (consumer testing + tailored supplement subscriptions) and digital channels as primary growth drivers.
Novo Nordisk, a leading global pharmaceutical company, regularly purchases high-purity recombinant human growth hormone (somatropin) from its active pharmaceutical ingredient (API) supplier, Lonza Group, under long-term supply agreements. A typical transaction might involve Novo Nordisk procuring a batch of the hormone for approximately $50,000 USD per kilogram of the purified API, which is then formulated into their branded injectable products like Norditropin®.

The formulated somatropin product, Norditropin®, is prescribed and dispensed to patients at major hospital pharmacies and specialized clinics, such as those within the Cleveland Clinic health system. For the end-user, the cost is not per kilogram but per dosage. A single 5mg prefilled pen, containing a month's supply for a pediatric patient, is used by the patient at a cost of approximately $1,200 USD per unit, making it a critical, though expensive, treatment for conditions like growth hormone deficiency.
Asia is a major growth engine for hormone-related supplements both because of sheer population scale and rapidly expanding middle-class health spend. Broad Asia-Pacific supplement market analys estimate high single- to double-digit regional growth across formats, with country-level dynamics varying: Japan, South Korea and Australia lead in premiumization and regulatory sophistication while China, India and Southeast Asian markets show faster volume growth, expansion of local contract manufacturers, and strong e-commerce uptake. The Asia Pacific supplements market has been cited repeatedly as a large and rapidly growing regional market in 2024 to 2025 studies, and multinational players are expanding manufacturing footprints and private-label capacity in the region to shorten supply chains and serve both domestic and export demand. For hormone supplements specifically, demand for melatonin, testosterone support and anti-aging formulations in urban centers is rising, while local herbal traditions remain a complementary channel in many countries.
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Hormone Supplements by Type:
Melatonin Supplements

DHEA Supplements

Testosterone Boosters

Thyroid Support

Others

Hormone Supplements by Product:
Capsules/Tablets

Powder

Liquid Drops

Gummy Candies

Others

Hormone Supplements by Dosage:
Micro Dose (10 mg / serving)

Hormone Supplements by Usage:
Sleep and Relaxation Support

Sport and Fitness Performance

Metabolic and Weight Management

Men's and Women's Health

Others

Hormone Supplements by Source Origin:
Synthetic Hormones

Bioidentical Hormones

Plant Derived Phytohormones

Animal Derived Hormones

Others

Hormone Supplements by Application:
Supermarkets

Specialty Stores

Online Sales

Others

Global Top 20 Key Companies in the Hormone Supplements Market
Natures Bounty

NOW Foods

Life Extension

Natrol

Thorne HealthTech

Douglas Laboratories

Swanson Health Products

GNC Holdings

Pure Encapsulations

BioMatrix

Jarrow Formulas

NutraScience Labs

Gaia Herbs

Irwin Naturals

NaturesPlus

Designs for Health

Integrative Therapeutics

HUM Nutrition

NutraBio Labs

Vital Nutrients

Regional Insights
Southeast Asia combines strong digital penetration with younger demographics in many markets and rapidly rising per-capita spend on wellness. Indonesia is singled out as one of the faster-growing national supplement markets in ASEAN: recent regional market reports and country studies estimate Indonesias total supplement market in the low-to-mid billions USD in 20232024 (multiple trackers show ~USD 2.53.3 billion range for 2024 depending on definitions), and market growth in Indonesia is supported by social commerce, mobile retail and growing local manufacturing capability. Across ASEAN, e-commerce, social-commerce and cross-border platform sales (regional marketplaces and direct-to-consumer imports) are the primary distribution accelerants for hormone-adjacent supplements, while regulatory heterogeneity (different permitted ingredients, labelling and registration rules) creates both compliance cost and market-entry friction. Private label and CMOs in China and Southeast Asia are important suppliers to global and regional brands.
The category faces several structural challenges: regulatory risk (claims and ingredient restrictions vary widely by country and enforcement has tightened following safety investigations, particularly for childrens melatonin products); supply-chain quality control (active ingredient impurities and variable potency have driven recalls and platform blocks); reputational risk from celebrity/influencer product claims that imply drug-like effects; price pressure from commoditized private-label manufacturers; and the technical complexity of preserving hormone-active stability in consumer formats (requiring robust formulation and QC). Securing clear clinical evidence for benefit or at minimum robust safety data and quality certifications has become essential for mainstream retail acceptance and for passing platform (marketplace) safety checks.
Manufacturers and brands should prioritize three practical moves: first, invest in certified third-party testing and transparent labeling to differentiate on quality; second, lean into formats and channels with higher margin and trust (clinically validated capsules, pharmacy channels, telehealth bundling) while limiting unverified therapeutic claims; third, balance regional manufacturing footprints to reduce lead times for Asia markets and to manage regulatory differences. Companies should model manufacturing economics conservatively maintain gross margins under 30% at the factory level while investing in QA/regulatory spend and develop contingency supply agreements for key active ingredients to avoid single-source risk. Digital marketing and subscription models remain high-ROI tactics in ASEAN; in Indonesia specifically, video and social commerce formats are a primary growth vector.

Product Models
Hormone supplements are formulations designed to balance or support the bodys natural hormone levels, often used to improve sleep, energy, mood, metabolism, or reproductive health.
Melatonin supplements help regulate sleep-wake cycles by mimicking the naturally occurring hormone melatonin, which the brain produces in response to darkness. Notable products include:
Natrol Melatonin Natrol Inc.: Fast-dissolve tablets that promote better sleep and relaxation.
Nature Made Melatonin Pharmavite LLC: USP-verified formula supporting restful sleep.
NOW Melatonin NOW Foods: Vegan capsules aiding natural circadian rhythm support.
Life Extension Melatonin 3mg Life Extension: Controlled-release tablet for sustained nighttime support.
Solgar Melatonin Solgar Inc.: Non-GMO formula designed for better sleep onset.
Dehydroepiandrosterone (DHEA) supplements help restore levels of this naturally produced adrenal hormone, often linked with aging, stress response, and hormonal balance in men and women. Examples include:
Pure Encapsulations DHEA Pure Encapsulations: Hypoallergenic capsules supporting adrenal health.
Swanson DHEA Swanson Health Products: Designed to enhance stamina and mood.
Natures Lab DHEA Natures Lab: Supports balanced hormone production and wellness.
Country Life DHEA Country Life Vitamins: Gluten-free hormone balance supplement.
Designs for Health DHEA Designs for Health: Practitioner-grade formula for adrenal restoration.
Testosterone boosters are supplements formulated to naturally support testosterone production, which may enhance muscle mass, energy, and overall performance. Notable products include:
Prime Male Roar Ambition Ltd.: Aimed at restoring testosterone levels in aging men.
TestoFuel Roar Ambition Ltd.: Boosts muscle growth and recovery through natural ingredients.
EVLTEST EVLUTION Nutrition: Supports muscle performance and hormonal health.
TestRX Leading Edge Health: Targets natural testosterone production for strength
Six Star Testosterone Booster Iovate Health Sciences: Enhances performance and muscle recovery.
Thyroid support supplements are formulated with vitamins, minerals, and herbal extracts that promote healthy thyroid hormone production and metabolism, supporting energy, weight control, and mood balance. Notable products include:
ThyroScript Herbalogic: A natural herbal blend supporting optimal thyroid hormone balance and energy levels.
ThyroSense Natural Factors: Formulated with adaptogenic herbs to maintain healthy thyroid and adrenal interaction.
ThyroMate ThyroMate Inc.: Multivitamin-based thyroid complex supporting mood, metabolism, and energy.
Thyroid Health Capsules Swanson Health Products: Balanced nutrient blend for optimal thyroid and energy levels.
NutraChamps Thyroid Support NutraChamps: Promotes hormonal harmony and vitality.

Hormone supplements are a commercially attractive but increasingly scrutinized subsegment of the global supplements market. Given steady consumer demand for sleep, metabolic and anti-aging products paired with rising e-commerce in Asia and ASEAN the category will continue expanding at mid-single-digit to low-double-digit rates depending on product subsegment. Near-term risks are regulatory and quality-related, and firms that invest in transparency, compliant claims and manufacturing robustness will capture the higher-trust premium channels and most durable market share.

Investor Analysis
Investors should view the hormone supplements subcategory as a growth-adjacent niche within the much larger supplements market, with particular upside in sleep (melatonin formulations), male-health (testosterone support), and personalized metabolic/weight support products. How: Investment value is created by backing companies with rigorous quality control, scalable regional manufacturing (Asia/ASEAN footprint), proprietary clinical evidence or differentiated formulations, and strong DTC/e-commerce distribution. Why: The market fundamentals rising consumer wellness spend in Asia and ASEAN, strong digital channels, and modular manufacturing economies of scale create repeatable revenue and margin expansion opportunities, but regulatory and reputational risk mean value accrues to companies that can demonstrate quality and clear claims. Investors should prioritize capex-light, asset-light models (brand + CMO partnerships) or mid-cap companies with diversified manufacturing and solid QA certifications.
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5 Reasons to Buy This Report
To obtain a focused market sizing and volume estimate for hormone supplements in 2024 and an actionable forecast baseline through 2031 that is ready for investor modelling.
To understand Asia and ASEAN market dynamics and distribution channels that are driving near-term growth.
To benchmark realistic factory economics (COGS, gross profit per kg, and per-component cost breakdown) for financial planning and M&A diligence.
To access a curated list of recent regulatory and safety developments that materially affect product strategy and market access.
To get strategic recommendations for product, manufacturing and go-to-market moves tailored to high-growth Asia and ASEAN markets.
5 Key Questions Answered
What was the implied global shipped volume from the 2024 market value and the assumed price?
What are representative factory economics (COGS per kg, gross profit per kg, and a realistic per-component COGS breakdown)?
How do Asia and ASEAN market structures, e-commerce penetration and regulatory environments differ, and what does that mean for market entry?
Which product subsegments (sleep, male health, metabolic, thyroid support) capture the largest downstream demand share today?
Which operational and compliance investments materially reduce regulatory and reputational risk while preserving margin?
Chapter Outline
Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by region, product type, application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: key insights, key emerging trends, etc.
Chapter 3: Manufacturers competitive analysis, detailed analysis of the product manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 4: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 5 & 6: Sales, revenue of the product in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 7: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 8: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 9: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 10: The main points and conclusions of the report.

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