Press release
Small Interfering RNA (siRNA) Therapeutics Market to Benefit from Rising Government Funding and Increasing Research in Precision-Based Treatments
InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Global Small Interfering RNA (siRNA) Therapeutics Market - (By Type (Liposome-Based Systemic Therapy, Nanoparticle-Based Systemic Therapy, Other), By Application (Hospital, Research Institutions, Pharmaceutical and Biotechnology Companies, Academic Institutions, Other)), Trends, Industry Competition Analysis, Revenue and Forecast To 2031."The Small Interfering RNA (siRNA) Therapeutics Market Size is valued at USD 1.6 Bn in 2023 and is predicted to reach USD 4.89 Bn by the year 2031 at a 15.0% CAGR during the forecast period for 2024-2031.
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Small interfering RNA (siRNA) therapeutics represent a transformative advancement in gene silencing technology, offering precise and targeted treatment approaches for a broad spectrum of diseases by selectively inhibiting the expression of disease-associated genes. Market growth is being driven by an increasing number of clinical trials, shorter preclinical development timelines, rising government funding for research and innovation, and the presence of well-established healthcare infrastructures in key regions. The growing global prevalence of cancer-one of the leading causes of mortality-has further intensified interest in siRNA therapeutics, as these molecules demonstrate strong potential in modulating gene expression to address underlying disease mechanisms.
However, the market faces several challenges that may hinder its expansion. Complex and evolving regulatory requirements for therapy approval, coupled with high development and manufacturing costs, continue to pose significant barriers. Additionally, technical limitations related to delivery systems, stability, and pharmacokinetics present ongoing challenges in siRNA therapeutic development.
Despite these constraints, growing investments from pharmaceutical companies, biotechnology firms, and academic research institutions are driving innovation, advancing clinical translation, and accelerating commercialization efforts. These developments are expected to create substantial opportunities for sustained growth and technological advancement within the siRNA therapeutics market.
List of Prominent Players in the Small Interfering RNA (siRNA) Therapeutics Market:
• GE Healthcare Dharmacon, Inc.
• OPKO Health, Inc.
• Alnylam Pharmaceuticals
• Arrowhead Research Corp
• Sanofi Genzyme
• Genecon Biotechnologies Co., Ltd.
• Arbutus Biopharma Corp
• Silence Therapeutics AG
• Sylentis S.A.
• Olix Pharmaceuticals
• GlaxoSmithKline
• Isis Pharmaceuticals/ Ionis Pharmaceuticals
• BenitecBiopharma Ltd.
• Bio-Path Holdings Inc.
• Calando Pharmaceuticals
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Market Dynamics
Drivers:
The growth of the small interfering RNA (siRNA) therapeutics market is primarily driven by the rising demand for precision medicine aimed at addressing the increasing prevalence of genetic disorders and viral infections. Technological advancements in delivery systems-such as nanoparticle- and liposome-based platforms-have substantially enhanced the stability, bioavailability, and therapeutic efficacy of siRNA-based treatments.
Supportive regulatory frameworks, coupled with increased government and private sector funding for biopharmaceutical research, are further catalyzing market expansion. Additionally, strategic collaborations and partnerships among pharmaceutical companies, biotechnology firms, and academic research institutions are fostering innovation and accelerating the clinical translation of siRNA therapeutics. Growing patient awareness and preference for targeted and personalized treatment approaches continue to reinforce the market's upward trajectory.
Challenges:
Despite its strong growth potential, the siRNA therapeutics market faces notable challenges. High production and development costs represent significant barriers to entry, particularly for smaller firms. Ensuring the efficient delivery and sustained stability of siRNA molecules within the human body remains a critical technical obstacle affecting therapeutic effectiveness.
Furthermore, the complex and lengthy regulatory approval processes, coupled with the substantial investment required for large-scale clinical trials to establish safety and efficacy, contribute to extended commercialization timelines. These factors collectively pose challenges to broader market penetration and profitability.
Regional Trends:
North America is expected to maintain a leading position in the global siRNA therapeutics market, supported by a growing number of clinical trials, frequent product launches, robust healthcare infrastructure, and substantial public and private investments in research and development. The region's strong regulatory support and increasing healthcare expenditure further enhance market growth.
Meanwhile, the Asia-Pacific (APAC) region is anticipated to experience significant expansion, driven by rapid urbanization, improvements in healthcare infrastructure, rising disposable incomes, and favorable government initiatives promoting R&D in biopharmaceuticals. Increasing public awareness of the therapeutic potential of siRNA in treating complex diseases, including cancer and cardiovascular disorders, is also contributing to accelerated market adoption across the region.
Recent Developments:
• In April 2024, Wave Life Sciences reported ongoing progress in their partnership with GSK and achieved notable breakthroughs in siRNA and RNA editing. Wave partnered with GSK and identified its initial two programs for further development after successfully validating their targets. These applications utilized Wave's advanced GalNAc-siRNA format, which is the next generation in the field of hepatology.
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Segmentation of Small Interfering RNA (siRNA) Therapeutics Market-
By Type-
• Liposome-Based Systemic Therapy
• Nanoparticle-Based Systemic Therapy
• Other
By Application-
• Hospital
• Research Institutions
• Pharmaceutical and Biotechnology Companies
• Academic Institutions
• Other
By Region-
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa
Read Overview Report- https://www.insightaceanalytic.com/report/small-interfering-rna-sirna-therapeutics-market/2629
About Us:
InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.
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InsightAce Analytic Pvt. Ltd.
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