Press release
United States Patient Derived Xenograft (PDX) Models Market 2025 | Growth Drivers, Competitive Landscape & Investment Opportunities
Market Size and GrowthPatient Derived Xenograft (PDX) Models Market is expected to reach at a high CAGR during the forecast period (2024-2031).
Key Development:
United States: Recent Industry Developments
✅ In October 2025, Crown Bioscience expanded its U.S. presence by inaugurating a new Model Development Center in Kannapolis, North Carolina. This facility boasts the world's largest commercially available PDX collection and approximately 1,000 tumor organoid models, enhancing capabilities across 35 cancer indications.
✅ In October 2025, XenoSTART and Minerva Imaging announced an expanded partnership to deliver an integrated PDX-Radiopharma-DD platform. This collaboration aims to advance translational oncology by combining PDX models with radiopharmaceutical development, facilitating more precise cancer therapies.
Japan: Recent Industry Developments
✅ In October 2025, Japan's National Cancer Center launched the J-PDX Library, aiming to accelerate drug discovery and development by providing a comprehensive collection of PDX models derived from Japanese cancer patients. This initiative supports the rapid delivery of more effective anticancer drugs to patients.
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Patient-Derived Xenograft (PDX) models are preclinical cancer models created by implanting human tumor tissues into immunodeficient mice. They closely mimic the patient's tumor biology, enabling accurate evaluation of drug efficacy, biomarker discovery, and personalized cancer therapy development.
Recent Mergers and acquisitions:
United States: Recent M&A Activity in PDX Models
✅ In October 2025, Charles River Laboratories announced the acquisition of Oncodesign, a French company specializing in oncology and immuno-oncology services. This strategic move enhances Charles River's capabilities in PDX model development, expanding its portfolio to include a broader range of tumor types and related services.
✅ In October 2025, Champions Oncology entered into a licensing agreement with Weill Cornell Medicine to distribute and commercialize an extensive bank of hematological PDX models. This collaboration aims to accelerate research and development in precision oncology by providing access to a diverse set of patient-derived models.
Japan: Recent M&A Activity in PDX Models
✅ In October 2025, JSR Corporation, a Japanese life sciences company, expanded its PDX model offerings by acquiring a portfolio of prostate cancer PDX models from CoMotion at the University of Washington. This acquisition strengthens JSR's position in the oncology research market by broadening its range of clinically relevant models.
Key Players:
=> Charles River Laboratories, Envigo, JSR Corporation (Crown Bioscience Inc.), Champions Oncology, Inc., EPO Berlin-Buch GmbH, Hera BioLabs, Horizon Discovery Group plc, WuXi AppTec, BEIJING IDMO Co. Ltd., Shanghai ChemPartner Co., Ltd. among others.
Growth Forecast Projected:
The Global Patient Derived Xenograft (PDX) Models Market is anticipated to rise at a considerable rate during the forecast period, between 2024 and 2031. In 2023, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.
Research Process:
Both primary and secondary data sources have been used in the global Patient Derived Xenograft (PDX) Models Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.
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Key Segments:
➥ By Type: Mice Model, Rats Model, Gastrointestinal Tumor Model, Gynecological Tumor Model, Respiratory Tumor Model, Other Tumor Model
➥ By Application: Preclinical Drug Development, Biomarker Analysis, Basic Cancer Research
➥ By End-User: Pharmaceutical & Biotechnology Companies, Contract Research Organizations (CROs), Academic & Research Institutions, Others
Regional Analysis for Patient Derived Xenograft (PDX) Models Market:
⇥ North America (U.S., Canada, Mexico)
⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)
⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)
⇥ South America (Colombia, Brazil, Argentina, Rest of South America)
⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)
Benefits of the Report:
Chapter 1: Sets the stage by outlining the report's coverage, summarizing key market segments by region, product type, and application. Presents a snapshot of market sizes, growth potential across segments, and anticipated industry evolution both short and long term.
Chapter 2: Highlights pivotal market insights and uncovers the most significant emerging trends driving change within the industry.
Chapter 3: Offers an in-depth look at the competitive landscape among Patient Derived Xenograft (PDX) Models producers, including revenue shares, strategic moves, and recent mergers and acquisitions.
Chapter 4: Presents comprehensive profiles of the market's key players, delving into details such as revenue, profit margins, product portfolios, and company milestones.
Chapters 5 & 6: Analyze Patient Derived Xenograft (PDX) Models revenue at both regional and country levels, providing quantitative breakdowns of market sizes, growth opportunities, and development prospects worldwide.
Chapter 7: Focuses on different market segments by type, examining their individual sizes and potential, guiding readers toward high-impact, untapped market areas.
Chapter 8: Explores segmentation by application, evaluating industry growth potential in various downstream markets and pinpointing promising sectors for expansion.
Chapter 9: Provides a thorough review of the industry's supply chain mapping out both upstream and downstream activities.
Chapter 10: Concludes with a summary of the report's key findings and highlights the most critical takeaways for industry stakeholders.
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