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Evolving Market Trends In The Patient Derived Xenograft (PDX) Models Industry: Advancements in Patient-Derived Xenograft (PDX) Models and Bioluminescence Imaging for Glioblastoma Research
Patient Derived Xenograft (PDX) Models Market
What Is the Expected Patient Derived Xenograft (PDX) Models Market Size During the Forecast Period?
The patient-derived xenograft (PDX) models market, valued at $0.4 billion in 2024, is expected to grow to $0.47 billion in 2025, reflecting a compound annual growth rate (CAGR) of 16.4%. Growth in recent years has been driven by increased research and development investments, regulatory support, partnerships and collaborations, a rise in contract research organizations (CROs), and the growing number of cancer cases.
The patient derived xenograft (PDX) models market is expected to experience significant growth in the coming years, reaching $0.85 billion by 2029, with a compound annual growth rate (CAGR) of 16.0%. The growth is driven by the demand for personalized medicine, increased need for humanized PDX models, rising cancer incidence, focus on precision oncology, and growing investment in cancer research. Key trends include technological advancements, rising demand for humanized PDX models, collaborative research initiatives, increased funding for cancer research, and an expanding focus on immuno-oncology.
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What Are the High-Growth Segments in the Patient Derived Xenograft (PDX) Models Market?
The patient derived xenograft (PDX) models market covered in this report is segmented -
1) By Type: Mice Models, Rat Models
2) By Technique: Heterotopic Implantation, Orthotropic Implantation
3) By Tumor Type: Gastrointestinal Tumor Models, Lung Tumor Models, Hematological Tumor Models, Gynecological Tumor Models, Respiratory Tumor Models, Urological Tumor Models, Other Tumor Models
4) By Application: Preclinical Drug Development, Precision Medicine, Co-Clinical Trials, Basic Cancer Research
5) By End-User: Academic And Research Organizations, Contract Research Organizations, Pharmaceutical And Biotechnological Companies, Other End-Users
Subsegments:
1) By Mice Models: Immunodeficient Mice Models (Nud*e Mice, SCID Mice), Humanized Mice Models, Genetically Modified Mice Models
2) By Rat Models: Immunodeficient Rat Models, Humanized Rat Models, Genetically Modified Rat Models
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What Key Drivers Are Expected to Influence Future Patient Derived Xenograft (PDX) Models Market Growth?
The growing demand for personalized medicine is expected to drive the expansion of the patient-derived xenograft (PDX) models market. Personalized medicine focuses on customizing medical treatments based on individual patient characteristics, such as genetics, environment, and lifestyle. This demand is rising due to advancements in genomic research, which allow for treatments tailored to an individual's genetic makeup, resulting in more precise and effective healthcare outcomes.
Which Companies Hold the Largest Share Across Different Patient Derived Xenograft (PDX) Models Market Segments?
Major companies operating in the patient derived xenograft (PDX) models market are Laboratory Corporation of America Holdings, WuXi AppTec Co. Ltd., Charles River Laboratories International Inc., The Jackson Laboratory, Inotiv Inc, Biocytogen Pharmaceuticals Co. Ltd., Taconic Biosciences Inc, BioDuro-Sundia Inc, Horizon Discovery Ltd., Crown Bioscience Inc., Champions Oncology Inc., Oncodesign Services S.A, Genesis Biotechnology Group LLC., Creative Animodel, Abnova Corp., Certis Oncology Solutions Inc., Xentech, Aragen Bioscience Inc., EPO Experimental Pharmacology & Oncology Berlin-Buch GmbH., Urosphere, Hera BioLabs, InnoSer, Pharmatest Services Ltd., IVRS AB, Altogen Inc
What Trends Are Expected to Dominate the Patient Derived Xenograft (PDX) Models Market in the Next 5 Years?
Major companies in the patient-derived xenograft (PDX) models market are introducing advanced models integrated with in vivo bioluminescence imaging to facilitate real-time observation of tumor development. This imaging approach supports PDX models by enabling non-invasive monitoring of tumor spread and responses to treatments, which improves preclinical drug research effectiveness. For example, in March 2024, India-based InVitro Research Solutions Private Limited, a Contract Research Organization (CRO), introduced a new orthotopic model of human glioblastoma in NSG-SGM3 mice using PDX and in vivo bioluminescence imaging. This model aims to support personalized glioblastoma treatment and plays a vital role in studying the disease's biology and evaluating new therapies.
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What Are the Emerging Geographies for The Patient Derived Xenograft (PDX) Models Market Growth?
North America was the largest region in the patient derived xenograft (PDX) models market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the patient derived xenograft (PDX) models market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the Patient Derived Xenograft (PDX) Models Market?
2. What is the CAGR expected in the Patient Derived Xenograft (PDX) Models Market?
3. What Are the Key Innovations Transforming the Patient Derived Xenograft (PDX) Models Industry?
4. Which Region Is Leading the Patient Derived Xenograft (PDX) Models Market?
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