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2025-2034 Vutrisiran Market Outlook: Key Drivers, Emerging Challenges, and Strategic Insights

09-16-2025 08:34 AM CET | Health & Medicine

Press release from: The Business Research Company

Vutrisiran Market

Vutrisiran Market

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What Will the Vutrisiran Industry Market Size Be by 2025?
The market for vutrisiran has experienced a swift expansion in the past few years. The projected growth will see it jump from $0.6 billion in 2024 to $0.67 billion in 2025, with a compound annual growth rate (CAGR) of 11.8%. This growth during the historical period can be credited to factors like increased knowledge of hereditary transthyretin amyloidosis, a surge in clinical trials, enhanced healthcare expenditures, a preference for non-invasive methods of administration among patients, and an increase in genetic disorders.

What's the Long-Term Growth Forecast for the Vutrisiran Market Size Through 2029?
The market size for vutrisiran is anticipated to experience a significant increase in the upcoming years, projected to reach "$1.06 billion in 2029, with a compound annual growth rate (CAGR) of 12.0%. Factors contributing to this surge in the forecast period include an increase in the accessibility to healthcare, a higher frequency of chronic illnesses, more funding for research and development, a greater emphasis on individualized medicines, and growing knowledge about diseases. Key trends during this forecast period encompass advancements in combination therapy, the application of targeted therapy, progress in personalized medicine, advancements in digital health technologies, and breakthroughs in biotechnology.

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What Are the Key Growth Drivers Fueling the Vutrisiran Market Expansion?
The surge in research and development spending is predicted to boost the vutrisiran market's expansion. Research and development encompass the systematic exploration and experimentation to advance and enhance products, services, or procedures. The surge in R&D investment can be attributed to government programs and funding, burgeoning healthcare and pharmaceutical necessities, sustainability, and ecological apprehensions. Funding for R&D enables pharmaceutical companies to carry out clinical trials, illustrating the drug's long-term advantages and safety, resulting in wider regulatory approvals. Moreover, advancements in RNA interference (RNAi) technology enhance the precision of the drug, minimize side effects, and increase patient acceptance. For example, Eurostat, a Luxembourg-based EU statistical office, reported in December 2023 that the EU's R&D spending grew to €352 billion ($384.42 billion) in 2022, a 6.34% jump from €331 billion ($361.48 billion) the previous year. Therefore, the rise in research and development investment is influencing the vutrisiran market's growth.

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What Are the Key Trends Driving Vutrisiran Market Growth?
A key development in the vutrisiran market is the targeted advancement of ground-breaking treatments like subcutaneous RNAi therapeutic strategies, as a more accessible, fewer dosing solution for managing hereditary transthyretin-mediated (hATTR) amyloidosis. The treatment utilizes RNA interference technology, injected under the skin, and is engineered for prolonged release. This approach guarantees steady drug levels over prolonged periods, enhancing convenience for patients and facilitating better adherence to treatment for polyneuropathy associated with hereditary transthyretin-mediated (hATTR) amyloidosis. For example, US-based biopharmaceutical firm, Alnylam Pharmaceuticals, announced in June 2022, that the Food and Drug Administration (FDA) had approved vutrisiran (AMVUTTRA) for the treatment of polyneuropathy in adults with hereditary transthyretin-mediated (hATTR) amyloidosis. The drug significantly enhances neuropathy symptoms and halts the progression of the disease. Over half of patients in the HELIOS-A Phase 3 study witnessed either a reversal or halt in disease symptoms. AMVUTTRA demonstrates a strong safety performance, with no instances of drug-related discontinuations or deaths, and a dosing plan that could enhance patient adherence.

How Is the Vutrisiran Market Segmented?
The vutrisiran market covered in this report is segmented -

1) By Drug Class: Antisense Oligonucleotide, Nucleic Acids, Nucleotide, Nucleoside, Other Drug Classes
2) By Route Of Administration: Oral, Injectable, Subcutaneous
3) By Patient Demographics: Pediatric, Adult, Geriatric
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies, Other Distribution Channels

Subsegments:
1) By Antisense Oligonucleotide: Single-Stranded Antisense Oligonucleotides, Double-Stranded Antisense Oligonucleotides
2) By Nucleic Acids: DNA-based Nucleic Acids, RNA-based Nucleic Acids
3) By Nucleotide: Purine Nucleotides, Pyrimidine Nucleotides
4) By Nucleoside: Purine Nucleosides, Pyrimidine Nucleosides
5) By Other Drug Classes: Peptide-Based Drugs, Protein Therapeutics

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Which Companies Are Leading the Charge in Vutrisiran Market Innovation?
Major companies operating in the vutrisiran market are Alnylam Pharmaceuticals Inc

Which Regions Are Leading the Global Vutrisiran Market in Revenue?
North America was the largest region in the vutrisiran market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the vutrisiran market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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4.Consultants & Analysts - To support market entry, expansion strategies, and client advisory work.

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With over 15,000+ reports from 27 industries covering 60+ geographies, The Business Research Company has built a reputation for offering comprehensive, data-rich research and insights. Our flagship product, the Global Market Model delivers comprehensive and updated forecasts to support informed decision-making.

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