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Vutrisiran Market Size Forecasted To Achieve 1.08 Billion By 2029 With Steady Growth

06-18-2025 06:51 AM CET | Health & Medicine

Press release from: The Business Research Company

Vutrisiran

Vutrisiran

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What Is the Vutrisiran Market Size and Projected Growth Rate?
The market for vutrisiran has experienced significant expansion in the past few years. Projections indicate it will increase from a worth of $0.60 billion in 2024 to $0.68 billion in 2025, presenting a compound annual growth rate (CAGR) of 12.8%. The surge seen in the historic period is linked to a growing understanding of hereditary transthyretin amyloidosis, an increase in clinical trials, heightened healthcare expenditures, an upswing in patient preference for non-invasive administration techniques, and a rise in genetic disorders.

The market size for vutrisiran is projected to experience accelerated growth in the coming years, expanding to $1.08 billion in 2029 with a compound annual growth rate (CAGR) of 12.4%. Factors contributing to this predicted growth during the forecast period include improved healthcare accessibility, an increase in chronic diseases, more investment in R&D, a heightened focus on individualized medicine, and an increased understanding of diseases. Some major trends for the forecast period are advancements in combination therapy, the embracing of targeted therapy, innovation in personalized medicine, progress in digital health technologies, and development in the biotechnology field.

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What Are the Major Segments in the Vutrisiran Market?
The vutrisiran market covered in this report is segmented -

1) By Drug Class: Antisense Oligonucleotide, Nucleic Acids, Nucleotide, Nucleoside, Other Drug Classes
2) By Route Of Administration: Oral, Injectable, Subcutaneous
3) By Patient Demographics: Pediatric, Adult, Geriatric
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies, Other Distribution Channels

Subsegments:
1) By Antisense Oligonucleotide: Single-Stranded Antisense Oligonucleotides, Double-Stranded Antisense Oligonucleotides
2) By Nucleic Acids: DNA-based Nucleic Acids, RNA-based Nucleic Acids
3) By Nucleotide: Purine Nucleotides, Pyrimidine Nucleotides
4) By Nucleoside: Purine Nucleosides, Pyrimidine Nucleosides
5) By Other Drug Classes: Peptide-Based Drugs, Protein Therapeutics

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What Are The Driving Vutrisiran Market Evolution?
The escalation in funding for research and development activities is predicted to boost the vutrisiran market's growth in the future. Research and development encompass systematic exploration and trials aimed at innovating and enhancing products, services, or processes. The factors contributing to the rise in research and development (R&D) investment include government-led initiatives and financial support, increased needs in healthcare and the pharmaceutical industry, sustainability drives, and environmental considerations. R&D financing permits pharmaceutical entities to undertake clinical trials that help demonstrate long-term benefits and safety of a medication, resulting in wider regulatory approvals. Moreover, advancements in RNA interference (RNAi) technology enhance the precision of the medication, minimize side effects, and promote patient acceptance. For example, data from Eurostat, the statistical office of the European Union based in Luxembourg, indicated that the European Union's R&D spending in 2022 increased to €352 billion ($384.42 billion), a 6.34% jump from €331 billion ($361.48 billion) in the preceding year. Hence, the escalating investment in R&D is fueling the expansion of the vutrisiran market.

Which Firms Dominate The Vutrisiran Market Segments?
Major companies operating in the vutrisiran market are Alnylam Pharmaceuticals Inc

What Are the Major Trends Shaping the Vutrisiran Market?
The Vutrisiran market's predominant trend is centered on the creation of cutting-edge remedies, like subcutaneous RNAi therapeutics, aimed at offering hassle-free, less regular dosing alternatives for the control of hereditary transthyretin-mediated (hATTR) amyloidosis. Subcutaneous RNAi therapeutics utilize RNA interference technology via a subcutaneous injection for extended release. This technique guarantees stable drug concentrations over a period to enhance patient convenience and compliance in managing polyneuropathy related to hereditary transthyretin-mediated (hATTR) amyloidosis. For example, Alnylam Pharmaceuticals, an American biopharmaceutical firm, declared in June 2022 that the FDA had approved Vutrisiran (AMVUTTRA) for adults' polyneuropathy treatment in cases of hereditary transthyretin-mediated (hATTR) amyloidosis. It brings substantial alleviation to neuropathy symptoms and stops the disease's progression. In the HELIOS-A Phase 3 clinical trial, over half the patients witnessed either a cessation or reversal of disease indications. AMVUTTRA also shows a favorable safety record, without any drug-related discontinuations or fatalities, and a dosing plan that could enhance patient adherence.

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Which Is The Largest Region In The Vutrisiran Market?
North America was the largest region in the vutrisiran market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the vutrisiran market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the Vutrisiran Market?
2. What is the CAGR expected in the Vutrisiran Market?
3. What Are the Key Innovations Transforming the Vutrisiran Industry?
4. Which Region Is Leading the Vutrisiran Market?

Why This Report Matters:

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