Antisense & RNAi Therapeutics Market: Major Trends Reshaping the Future of the Industry

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What Will the Antisense & RNAi Therapeutics Industry Market Size Be by 2025?
The market size of antisense and RNAi therapeutics has seen a swift expansion in the past few years. The market, standing at $1.75 billion in 2024 is projected to escalate to $1.93 billion in 2025, marking a compound annual growth rate (CAGR) of 10.2%. This growth during the historical period is fueled by an increase in funding, technological advancements, and an increase in healthcare spending, coupled with the rapid rise in the aging population and economic development in burgeoning markets.

What's the Long-Term Growth Forecast for the Antisense & RNAi Therapeutics Market Size Through 2029?
In the coming years, the antisense & RNAi therapeutics market is projected to experience accelerated expansion, escalating to "$3.11 billion in 2029 with a compound annual growth rate (CAGR) of 12.8%. This predicted surge over the forecast period can be attributed to factors such as enhanced healthcare access, an increased incidence of cancer and a rising demand for antisense and RNAi therapeutics provoked by the COVID-19 situation. Key trends anticipated over the forecast period encompass concentrated efforts towards researching and developing RNA therapeutics for the treatment of orphan diseases, employing nanoparticles, creating new and more effective antisense and RNAi therapeutics, and forming partnerships with other organizations for the innovation of products and boosting revenues.

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What Are the Key Growth Drivers Fueling the Antisense & RNAi Therapeutics Market Expansion?
The increased occurrence of conditions like coronary artery diseases, neurodegenerative disorders, and infectious diseases is expected to stimulate demand for the antisense & RNAi therapeutics market. Techniques employed to suppress genes, such as RNA interference and antisense oligonucleotides, are being deployed to treat a range of neurodegenerative diseases by rectifying mutant genes. In illustration, as per data released by the American Heart Association in January 2024, the age-adjusted mortality rate due to cardiovascular diseases climbed to 233.3 out of every 100,000, indicating a 4.0% increment from the preceding year. Therefore, the escalating occurrence of multiple neurodegenerative and infectious diseases is anticipated to fuel the expansion of the antisense & RNAi therapeutics market.

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Which Emerging Trends Are Transforming the Antisense & RNAi Therapeutics Market in 2025?
Renowned businesses in the segment of antisense & RNAi therapeutics are engaging in strategic activities like partnerships and collaborations to sustain in the progressively competitive market. For example, in January 2023, US-based Orbit Discovery Limited, which specializes in peptide discovery services, teamed up with UK-based SanegeneBio Inc., a company dedicated to developing novel RNAi-based drugs. Their joint venture aims to identify tissue-specific delivery of RNA therapeutics for efficient gene knockdown, with the end goal being the development of an advanced RNAi therapeutics portfolio. This collaboration involves both hit identification and cell-based internalization studies. Sanegene has the prerogative to further develop the hits originating from these screening processes, utilizing Orbit's exclusive technology for swift peptide lead discovery. Thanks to Orbit Discovery's distinctive peptide display engine, the screening of extensive peptide libraries is possible, thus expediting the discovery of pertinent peptide leads based on affinity and functional screens.

How Is the Antisense & RNAi Therapeutics Market Segmented?
The antisense & rnai therapeutics market covered in this report is segmented -

1) By Technology: RNA Interference, Antisense RNA
2) By Route Of Administration: Intravenous Injections, Intra-dermal Injections, Other Delivery Methods
3) By Indication: Oncology, Cardiovascular Diseases (CVDs), Respiratory Disorders, Neurological Disorders, Infectious Diseases, Other Indications

Subsegments:
1) By RNA Interference (RNAi): Small Interfering RNA (siRNA), Short Hairpin RNA (shRNA), Dicer-substrate siRNA, MicroRNA (miRNA) Based Therapeutics
2) By Antisense RNA: Antisense Oligonucleotides (ASOs), Morpholino Oligomers, Locked Nucleic Acids (LNAs), Gapmer Antisense Oligonucleotides

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Which Companies Are Leading the Charge in Antisense & RNAi Therapeutics Market Innovation?
Major companies operating in the antisense & RNAi therapeutics market include Biogen Inc., Ionis Pharmaceuticals Inc., Alnylam Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., Moderna Inc., Sanofi S.A., Dicerna Pharmaceuticals Inc., Arbutus Biopharma Corporation, Acuitas Therapeutics, Adhera Therapeutics Inc., EdiGene Inc., Sirnaomics Inc., Suzhou Ribo Life Science Co. Ltd, Biocon Limited, Quark Pharmaceuticals, GlaxoSmithKline Plc, Shanghai Junshi Biosciences Co. Ltd., AstraZeneca, Benitec Biopharma Limited, Silence Therapeutics, Dynacure, CN Bio Innovations, Sarepta Therapeutics, Mallinckrodt, Regeneron Pharmaceuticals Inc., Alcyone Lifesciences Inc., Bio-Path Holdings Inc, Calando Pharmaceuticals, Enzon Pharmaceuticals Inc, Celnova Pharma, Pfizer Inc., Taiba Pharma, Gen İlaç ve Sağlık Ürünleri A.Ş., Egypt Otsuka Pharmaceutical

Which Regions Are Leading the Global Antisense & RNAi Therapeutics Market in Revenue?
North America was the largest region in the antisense & RNAi therapeutics market in 2024. The regions covered in the antisense & RNAi therapeutics market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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