NGS-Based RNA Sequencing Market Size to Reach Significant Growth by 2031 - Exclusive Report by DataM Intelligence

Market Overview
According to DataM Intelligence, the global NGS-based RNA Sequencing Market reached a notable valuation in 2023 and is projected to grow at a CAGR of 19.7% during the forecast period 2024-2031. The market is driven by advancements in next-generation sequencing (NGS) technologies, enabling faster, cost-effective, and high-throughput RNA sequencing for transcriptomics and gene expression studies.
The market is propelled by increasing product approvals, automation in sample preparation, and growing genomic research in areas like rare genetic diseases and autoimmune disorders. North America dominates the market, supported by major players, robust research infrastructure, and significant investments in biomedical innovation.

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NGS-Based RNA Sequencing Market Overview
The NGS-based RNA Sequencing Market is forecasted to grow at a CAGR of 19.7% from 2024 to 2031. This technology identifies and sequences nucleotides in RNA, playing a critical role in transcriptomics and gene expression analysis. It offers faster, more reliable, and cost-effective solutions compared to traditional methods, with enhanced throughput capabilities.

The market is driven by the advantages of NGS-based RNA sequencing over conventional technologies, such as microarrays, including higher specificity, direct transcript quantification, and the ability to detect novel transcripts. These benefits make it a preferred method for researchers studying gene expression, alternative splicing, and disease mechanisms.

Key Highlights from the Report

Market Growth: The global NGS-based RNA Sequencing Market is projected to grow at a CAGR of 19.7% during 2024-2031.

North America Leadership: North America holds the largest market share at approximately 40% in 2024, driven by key players like Illumina, Inc., and strong government and private funding.

RNA Sequencing Platforms Dominate: The RNA sequencing platform & consumables segment holds the largest share, fueled by innovative platforms like Illumina HiSeq, Oxford Nanopore, and Ion Torrent.

Applications in Drug Discovery and Diagnostics: The market is segmented into drug discovery, diagnostics, precision medicine, and others, with drug discovery leading due to its role in identifying gene fusions and transcript isoforms.

Technological Advancements: Innovations like RNA interference (RNAi) and platforms such as SEQuoia RiboDepletion Kit by Bio-Rad enhance sequencing accuracy and efficiency.

COVID-19 Impact: The pandemic boosted market growth by increasing the use of RNA sequencing to study SARS-CoV-2 viral dynamics and pathogenesis.

RNA Sequencing Platforms & Consumables Lead with Significant Market Share
The NGS-based RNA Sequencing Market is segmented by product & services, technology, application, end-user, and region. By product & services, the RNA sequencing platform & consumables segment holds the largest share, approximately 45%, driven by advanced platforms like Illumina HiSeq, Oxford Nanopore Technologies, and PacBio IsoSeq.These platforms enable researchers to detect gene fusions, transcript isoforms, and single nucleotide variants with high precision. For instance, Agilent Technologies' SureSelect Strand-Specific RNA Library Preparation Kit supports whole-transcriptome sequencing, enhancing studies on gene expression and alternative splicing.

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Drug Discovery Leads Applications Amid Growing Genomic Research
By application, the market is categorized into drug discovery, diagnostics, precision medicine, and others. The drug discovery segment dominates with a 38% market share, driven by the rising prevalence of diseases like cancer and autoimmune disorders, where RNA sequencing aids in identifying novel therapeutic targets.
The technology's ability to analyze transcriptional activity and detect disease-specific changes fuels its adoption in precision medicine and diagnostics. End-users include biotechnology and pharmaceutical companies, research centers, academic and government institutes, and hospitals & clinics, with biotech and pharma companies leading at 42% due to their focus on innovative drug development.

North America Leads NGS-Based RNA Sequencing Market with 40% Share
North America holds the largest market share at 40% in 2024, driven by the presence of leading companies like Illumina, Inc., Thermo Fisher Scientific, and Agilent Technologies, alongside strong funding for genomic research. The U.S. leads due to early adoption of NGS technologies and high prevalence of diseases like rheumatoid arthritis, affecting over 1.3 million Americans in 2018. The region's advanced research infrastructure and collaborations between academia, industry, and government further accelerate market growth. Asia Pacific is the fastest-growing region, fueled by increasing investments in biotechnology and rising healthcare demands.

Major Companies
Key players driving market growth include:
Illumina, Inc.: Leading provider of NGS platforms like HiSeq, widely used for RNA sequencing.
Agilent Technologies, Inc.: Offers solutions like the SureSelect Strand-Specific RNA Library Preparation Kit.
Thermo Fisher Scientific Inc., Oxford Nanopore Technologies, PerkinElmer, Inc., F. Hoffmann-La Roche Ltd, Hamilton Company, and Takara Bio Inc.

Recent Developments
In May 2021, Bio-Rad Laboratories, Inc. launched the SEQuoia RiboDepletion Kit for NGS, enhancing assay efficiency by eliminating irrelevant ribosomal RNA from RNA-sequencing libraries. This development supports researchers in achieving more accurate sequencing results for genomic studies.

Contact Information:

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DataM Intelligence 4Market Research LLP
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USA: +1 877-441-4866
Email: Sai.k@datamintelligence.com
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