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Future of Cytokine-Based Therapies And Inhibitors Market: Size, Share & Forecasts to 2029

08-25-2025 09:57 AM CET | Health & Medicine

Press release from: The Business Research Company

Cytokine Based Therapies And Inhibitors

Cytokine Based Therapies And Inhibitors

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What Is the Projected Market Size Valuation of the Cytokine-Based Therapies And Inhibitors Market by 2025?
There has been consistent expansion in the market for cytokine-based therapies and inhibitors in recent years. The market, which was valued at $140.66 billion in 2024, is anticipated to surge to $146.95 billion in 2025, witnessing a compound annual growth rate (CAGR) of 4.5%. Factors contributing to the growth during the historical period include the escalating prevalence of autoimmune diseases, increased cancer rates, a surge in infectious disease cases, the rising demand for personalized medical treatments, advancements in the production of vaccines, and growing public awareness about immunotherapies.

What Is the Estimated Market Growth Value for the Cytokine-Based Therapies And Inhibitors Industry in 2029?
The market for cytokine-based therapies and inhibitors is predicted to undergo consistent expansion in the coming years, reaching a market size of $173.32 billion in 2029 with a compound annual growth rate (CAGR) of 4.2%. This predicted growth in the forecast period is linked to factors such as a rising global elderly population, the wide-spread acceptance of targeted therapies, the growing number of chronic inflammatory diseases, the broadening of clinical trial pipelines, the government's endorsement of immunology studies, and increased emphasis on patient safety and outcomes. The forecast period is also likely to see key trends like progress in protein engineering, the creation of multi-cytokine inhibitors, the application of artificial intelligence in drug discovery, the use of next-generation sequencing for biomarker discovery, the merging of digital health platforms, and improved formulation technologies for better stability.

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What Are the Growth Drivers and Opportunities in the Cytokine-Based Therapies And Inhibitors Market?
The escalating occurrences of autoimmune disorders, where the body's immune system mistakenly identifies its own healthy cells and tissues as alien invaders, are projected to fuel the expansion of the cytokine-based therapies and inhibitors market. This surge in autoimmune disorders can be attributed to alterations in diet, specifically an increased intake of excessively processed foods that have the potential to upset gut microbiota and impair immunoregulation. Cytokine-based therapies and inhibitors, which target specific cytokines involved in inflammation, are efficient in managing these autoimmune disorders. Citing an example, a 2024 survey study by Versorgungsatlas.de, a German based online healthcare information source, reported that out of 73,241,305 insured individuals in 2022, a total of 6,304,340 were diagnosed with at least a single autoimmune disease. This equates to a raw prevalence rate of 8.61%. Consequently, the burgeoning rate of autoimmune disorders is propelling the growth of the cytokine-based therapies and inhibitors market.

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What Are the Primary Segments Covered in the Global Cytokine-Based Therapies And Inhibitors Market Report?
The cytokine-based therapies and inhibitors market covered in this report is segmented -

1) By Type: Interleukins, Tumor Necrosis Factor, Epidermal Growth Factor, Interferon, Chemokine
2) By Application: Cancer And Malignancies, Inflammatory And Immune Disorders, Infectious Diseases, Asthma And Airway Inflammation, Other Applications
3) By End User: Hospitals, Clinics, Research Laboratories, Academic And Research Institutes, Specialty Centers, Other End Users

Subsegments:
1) By Interleukins: Interleukin-2, Interleukin-6, Interleukin-10, Interleukin-12, Interleukin-17, Interleukin-23
2) By Tumor Necrosis Factor (TNF): Tumor Necrosis Factor-Alpha Inhibitors, Tumor Necrosis Factor-Beta Inhibitors
3) By Epidermal Growth Factor (EGF): Epidermal Growth Factor Receptor Inhibitors, Human Epidermal Growth Factor Receptor 2 Inhibitors
4) By Interferon: Interferon-Alpha, Interferon-Beta, Interferon-Gamma
5) By Chemokine: C-C Chemokine Receptor Type 5 Antagonists, C-X-C Chemokine Receptor Type 4 Inhibitors, C-X-C Chemokine Receptor Type 1/2 Inhibitors

What Are the Top Growth Trends in the Cytokine-Based Therapies And Inhibitors Market?
Leading corporations in the cytokine-based therapy and inhibitor sector are putting their attention on pioneering treatments such as intravesical cytokine maintenance immunotherapy. This method addresses enhancing the persistence of comprehensive responses and minimizing recurrence rates in individuals with Bacillus Calmette-Guérin-resistant non-muscle invasive bladder cancer (BCG-resistant NMIBC). Intravesical cytokine maintenance immunotherapy implicates direct injection of immune-stimulating proteins into the bladder. It then involves extended maintenance dosing to continuously trigger local immune responses and control tumor regrowth. For instance, in April 2024, nogapendekin alfa inbakicept-pmln (Anktiva) received approval from the US government's regulatory authority, the Food and Drug Administration (FDA). This innovative cytokine-based therapy, used in conjunction with Bacillus Calmette-Guérin (BCG), is an advanced form of immunotherapy. It behaves as a fusion protein that targets interleukin-15 (IL-15) pathways, in turn activating immune cells such as natural killer (NK) cells and CD8-positive T cells. This approach corresponds with the principles of cytokine-based therapy, which employ signaling proteins like IL-15 to boost the body's immune monitoring and anti-tumor activities.

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Which Companies Are Shaping the Future of the Cytokine-Based Therapies And Inhibitors Market?
Major companies operating in the cytokine-based therapies and inhibitors market are Pfizer Inc., Johnson & Johnson, F. Hoffmann-La Roche Ltd, AbbVie Inc., Bayer AG, Novartis AG, Sanofi SA, Bristol-Myers Squibb Company, Thermo Fisher Scientific Inc., AstraZeneca Plc, GlaxoSmithKline plc, Eli Lilly and Company, Amgen Inc, Lonza Group AG, Cytiva, UCB S.A., Sartorius CellGenix GmbH, Biocon Limited, Bio-Techne Corporation, Miltenyi Biotec B.V. & Co. KG.

Which Region Holds the Largest Market Share in the Cytokine-Based Therapies And Inhibitors Industry?
North America was the largest region in the cytokine-based therapies and inhibitors market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cytokine-based therapies and inhibitors market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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