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Cryptococcosis Therapeutics Market to Record 5.3% CAGR Growth Through 2029 | Global Analysis Report

08-25-2025 09:44 AM CET | Health & Medicine

Press release from: The Business Research Company

Cryptococcosis Therapeutics

Cryptococcosis Therapeutics

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Cryptococcosis Therapeutics Market Outlook: How is the Market Expected to Grow by 2025?
The market size for cryptococcosis therapeutics has seen substantial growth in previous years. The market size is set to increase from $3.91 billion in 2024 to $4.13 billion in 2025, with a compound annual growth rate (CAGR) of 5.6%. The historic growth can be linked to the increase in human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) cases, greater acknowledgment of fungal infections, expanding accessibility of antifungal drugs, growth in global awareness and surveillance programs for fungal diseases, and the increase in health initiatives by non-governmental entities.

Cryptococcosis Therapeutics Market Forecast: What Size Will It Reach By 2029?
In the coming years, the cryptococcosis therapeutics market is anticipated to experience substantial growth, with its valuation anticipated to reach $5.07 billion by 2029, expanding at a compound annual growth rate (CAGR) of 5.3%. Factors such as increased funding for antifungal research and novel drug discovery, growing incidents of immunosuppressive conditions and therapies, a rise in global fungal disease incidence, and heightened demand for quick diagnostic tools and combination therapies are all contributors to this projected growth. Notable trends for the forecast period are the increasing preference for combination antifungal treatments, the emergence of next-generation antifungals featuring innovative mechanisms, comprehensive management of fungal diseases, the utilization of sophisticated drug delivery systems, and the adoption of artificial intelligence and machine learning in this field.

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Which Key Market Drivers Will Shape Cryptococcosis Therapeutics Industry Trends in 2025-2029?
The growing incidence of human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) is set to spur the expansion of the cryptococcosis therapeutics market. HIV/AIDS is a persistent, fatal disease resulting from a virus attacking the immune system, making the body susceptible to infections and illnesses. The increasing number of HIV/AIDS cases, particularly in regions with health services' restricted access, impedes early detection, regular treatment, and efficient prevention measures. Cryptococcosis therapeutics are effective in managing HIV/AIDS by dealing with opportunistic fungal infections commonly seen in immunocompromised individuals. These therapeutics help in avoiding severe complications such as cryptococcal meningitis, enhancing patient life quality and aiding in long-term disease handling. In 2024, the UK Health Security Agency reported a 51% increase in HIV diagnoses in England from the previous year - from 3,975 cases in 2022 to 6,008 in 2023. Hence, the escalating prevalence of HIV/AIDS is powering the expansion of the cryptococcosis therapeutics market. Boost in healthcare expenses are influencing the growth of the market, owing to better access to treatments, early diagnosis and surge in research funding. Healthcare expenditures include funds disbursed on medical services, treatments, equipment, research, and public health events to sustain or advance health results. The upswing in these expenses can primarily be attributed to an aging population, leading to the requirement for more medical attention, treatments, and extended healthcare services. This increase supports the cryptococcosis therapeutics market by providing extensive access to improved treatments, aids in early detection, and backs-up the search for more effective antifungal treatments. For instance, in 2024, the Centers for Medicare & Medicaid Services (CMS) reported that national health expenditures (NHE) surged up to 7.5%, amounting to $4.9 trillion in 2023, representing 17.6% of gross domestic product (GDP). Furthermore, between 2023 and 2032, it's projected the average annual rate of the NHE would increase by 5.6%, contributing to the rise of health spending's share of GDP from 17.3% in 2022 to 19.7% in 2032. Therefore, the increase in healthcare expenditure is stimulating the growth of the cryptococcosis therapeutics market.

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What Are the High-Growth Segments in the Cryptococcosis Therapeutics Market?
The cryptococcosis therapeutics market covered in this report is segmented -

1) By Drug Type: Branded, Generic
2) By Treatment: Amphotericin B, Flucytosine, Fluconazole, Other Treatments
3) By Route Of Administration: Oral, Intravenous, Inhalation
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
5) By End-User: Hospitals, Ambulatory Surgical Centers, Other End Users

Subsegments:
1) By Branded Drugs: Ambisome, Diflucan, Vfend, Noxafil, Cresemba
2) By Generic Drugs: Amphotericin B Deoxycholate, Fluconazole, Voriconazole, Itraconazole, Flucytosine

Which Global Trends Are Driving Cryptococcosis Therapeutics Market Expansion?
Leading businesses in the cryptococcosis therapeutics market are prioritizing the production of novel products and securing regulatory endorsements, such as those for azole antifungal medications, to enhance treatment, fight against resistance, and bolster their market standing. Azole antifungal drugs are a type of medication that restricts fungal growth by impeding the creation of ergosterol, an essential part of fungal cell membranes. For example, in December 2022, the Ministry of Health, Labour, and Welfare (MHLW) in Japan granted Asahi Kasei Pharma Corporation, a Japanese pharmaceutical firm, the authorization to produce and market Cresemba 100 mg capsule and Cresemba 200 mg intravenous infusion for treating severe fungal infections like aspergillosis, mucormycosis, and cryptococcosis. Cresemba (isavuconazonium sulfate) is an azole antifungal drug, available in the forms of capsules and intravenous infusion, which acts by interrupting ergosterol production in fungal cell membranes, culminating in the death of the fungal cells. The capsules are approved for use in patients aged 6 years and above (weighing a minimum of 16 kg), and the intravenous form can be administered from the age of 1 year.

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Who Are the Fastest-Growing Companies in the Cryptococcosis Therapeutics Industry?
Major companies operating in the cryptococcosis therapeutics market are Pfizer Inc., Merck & Co. Inc., Bayer AG, Bristol-Myers Squibb Company, Gilead Sciences Inc., Asahi Kasei Pharma Corporation, Astellas Pharma Inc., Bausch Health Companies Inc., Sun Pharmaceutical Industries Limited, Eisai Co. Ltd., Dr. Reddy's Laboratories Ltd., Cipla Limited, Takeda Pharmaceutical Company Limited, Luminex Corporation, Evotec SE, Kaken Pharmaceutical Co. Ltd., Basilea Pharmaceutica AG, Vical Incorporated, F2G Limited, Century Pharmaceuticals Ltd., LGM Pharma LLC, Zeon Health Industries Pvt. Ltd., Matinas BioPharma Holdings Inc.

What Is the Regional Outlook for the Cryptococcosis Therapeutics Market by 2029?
North America was the largest region in the cryptococcosis therapeutics market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cryptococcosis therapeutics market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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