Cementless Total Knee Systems Market Expansion Outlook: $5.77 Billion in 2029

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What Is the Projected CAGR for the Cementless Total Knee Systems Market from 2024 to 2025?
The market for cementless total knee systems has significantly expanded in the past few years. The market value is projected to increase from $4.44 billion in 2024 to $4.68 billion in 2025, with a compound annual growth rate (CAGR) of 5.6%. The remarkable growth during the historic period can be credited to factors such as increasing demand for durable implants from younger demographics, growing understanding of superior orthopedic solutions, rising acceptance of custom and patient-specific implants, increased knowledge about advanced orthopedic remedies, and a surge in the number of outpatient and ambulatory surgical centers.

What are the Expected Market Size and CAGR for Cementless Total Knee Systems by 2029?
The market size of cementless total knee systems is projected to witness robust expansion in the upcoming years, with a valuation set to reach $5.77 billion by 2029, growing at a compound annual growth rate (CAGR) of 5.3%. The growth in this period can be linked to the heightened focus on value-based healthcare, improved surgeon proficiency and training in cementless techniques, rising concerns related to complications from cement, an increased push towards early mobilization and shorter hospital stays, and the continued growth of customization through 3D printing and digital planning. Key trends in the forecast period will be driven by technological advancements in implant surfaces, the use of robotic-assisted surgery systems, progress in biomaterials and coatings, advances in patient-specific equipment, and the evolution of minimally invasive surgical methods.

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Which Factors Are Driving the Global Cementless Total Knee Systems Market Expansion?
The cementless total knee systems market is anticipated to expand due to the growing instances of orthopedic diseases. These diseases, affecting the musculoskeletal system- bones, joints, muscles, ligaments, and tendons- result in pain, limited movement, and functional impairment. Aging populations looking for long-lasting mobility solutions which reduce joint discomfort, improve movement, and promote an active lifestyle with lesser medical interventions are contributing to the surge in orthopedic diseases. Cementless total knee systems offer a lasting and biologically compatible answer for orthopedic ailments by promoting natural bone growth, reducing the chances of implant loosening, and restoring joint function without resorting to bone cement usage. For example, the Office for Health Improvement & Disparities, a UK government department, reported in January 2024 that the rate of people aged 16 and over who self-declared long-term musculoskeletal (MSK) disease, a form of orthopedic disease, saw an increase from 17.6% in 2022 to 18.4% in 2023. Hence, the rising instances of orthopedic diseases are fueling the growth of the cementless total knee systems market.

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Which Segment Currently Holds the Largest Share of the Cementless Total Knee Systems Market?
The cementless total knee systems market covered in this report is segmented -

1) By Component: Tibial Component, Femoral Component
2) By Fixation Method: Primary Fixation, Hybrid Fixation
3) By End User: Hospitals, Orthopedic Centers, Other End Users

Subsegments:
1) By Tibial Component: Fixed-Bearing Tibial Baseplates, Mobile-Bearing Tibial Baseplates, Modular Tibial Components, Monoblock Tibial Components, Porous-Coated Tibial Components, 3D-Printed Tibial Components
2) By Femoral Component: Posterior-Stabilized Femoral Components, Cruciate-Retaining Femoral Components, Ultra-Congruent Femoral Components, Asymmetric Femoral Components, Anatomical Femoral Components, Cementless Porous-Coated Femoral Components

Which Major Trends Are Shaping the Future of the Cementless Total Knee Systems Industry?
Leading corporations in the cementless total knee systems market are channeling their efforts into inventing cutting-edge technologies like TIDAL technology. The primary aim is to produce superior porous implants that improve bone integration and boost implant longevity. TIDAL technology, a sophisticated 3D-printed porous implant design, improves bone integration by bolstering mechanical strength, enhancing fatigue resistance, and ensuring ideal load distribution for an enduring implant stability. To cite an example, in April 2025, Restor3d Inc., a medical device firm based in the US, obtained FDA 510(k) clearance for their initial cementless patient-specific implant - the iTotal Identity CR 3DP porous total knee system. This trailblazing system applies innovative 3D printing and porous technology to enhance bone integration and stability. Simultaneously, its bespoke design, customized surgical tools, and pre-mapped surgical method aid surgeons in attaining greater precision and effectiveness.

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Which Key Players Dominate the Cementless Total Knee Systems Industry Globally?
Major companies operating in the cementless total knee systems market are Johnson & Johnson Services Inc., Stryker Corporation, Zimmer Biomet Holdings Inc., Smith & Nephew plc, Enovis Corporation, Globus Medical Inc., MicroPort Scientific Corporation, Medacta International SA, B. Braun Melsungen AG, Waldemar Link GmbH & Co. KG, restor3d Inc., implantcast GmbH, United Orthopedic Corporation, Signature Orthopaedics Pty Ltd, Gruppo Bioimpianti Srl, Permedica S.P.A., Evolutis SAS, Euromed Implants GmbH, X.NOV SAS, Beijing Chunli Zhongke Bio-Tech Co. Ltd.

What Are the Fastest-Growing Regions in the Cementless Total Knee Systems Market?
North America was the largest region in the cementless total knee systems market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cementless total knee systems market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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