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Graft Versus Host Disease (GVHD) Treatment Industry Outlook 2025-2029: Market Set to Cross $4.1 Billion Milestone

08-06-2025 11:39 AM CET | Health & Medicine

Press release from: The Business Research Company

Graft Versus Host Disease (GVHD) Treatment

Graft Versus Host Disease (GVHD) Treatment

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How Large Will the Graft Versus Host Disease (GVHD) Treatment Market Size By 2025?
In recent years, the market size for the treatment of graft versus host disease (GVHD) has seen a significant increase. The market, which was valued at $2.85 billion in 2024, is anticipated to reach $3.07 billion in 2025, marking a compound annual growth rate (CAGR) of 7.7%. This growth during the historic period is attributed to several factors including an upsurge in allogeneic transplantations, a growing incidence of acute GVHD, an increased rate of hematopoietic stem cell treatment, a surging demand for bone marrow transplants, a rising global prevalence of GVHD, an increase in chronic GVHD cases, advancements in medical technology, and a surge in the patient population.

How Big Is the Graft Versus Host Disease (GVHD) Treatment Market Size Expected to Grow by 2029?
The graft versus host disease (GVHD) treatment market is anticipated to experience significant expansion in the upcoming years, escalating to $4.1 billion in 2029 with a compound annual growth rate (CAGR) of 7.5%. This projected uptick during the forecast period is due to an increase in the number of allogeneic transplantations, a growing occurrence of acute GVHD, an escalating rate of hematopoietic stem cell treatments, an increased demand for bone marrow transplants, a rising incidence of GVHD globally, growth in chronic GVHD cases, technological advancements, and an expanding patient population. The forecast period is expected to witness major trends such as partnerships, investments, product approvals, and customizations.

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Which Key Market Drivers Powering Graft Versus Host Disease (GVHD) Treatment Market Expansion and Growth?
The surge in hematological disorders is anticipated to fuel the expansion of the graft versus host disease (GVHD) treatment market. Blood disorders, also known as hematological disorders, cover a broad spectrum of conditions that impact blood and its constituents, including red blood cells, white blood cells, platelets, and plasma. Various factors such as unhealthy lifestyle choices, genetic factors, and exposure to specific environmental toxins like radiation, chemicals, and pollutants are expanding the scope of hematological disorders. Treatment approaches developed for GvHD can provide significant benefits to patients with blood disorders, presenting fresh opportunities for immune modulation and enhanced disease management. For instance, the Leukemia & Lymphoma Society, a US-based healthcare organization, predicts that leukemia, lymphoma, and myeloma will result in the estimated deaths of 57,380 individuals in the US in 2023. This implies that approximately 157 individuals die each day, or more than six individuals succumb every hour to blood cancer in the US. Hence, the escalating occurrence of blood disorders is propelling the graft versus host disease (GVHD) treatment market.

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Which Fast-Growing Trends Are Poised to Disrupt the Graft Versus Host Disease (GVHD) Treatment Market?
Leading firms in the graft versus host disease (GVHD) treatment market are striving to get a competitive edge by devising advanced medications and seeking approval for their use in GVHD treatment. Product authorization is key in ensuring that medical products adhere to the required standards for safety, efficacy, and quality prior to being made available to the public. For example, in March 2023, Incyte corporation, a healthcare firm based in the US, produced a ruxolitinib extended-release (XR) tablet which had been sanctioned by the Food and Drug Administration, a healthcare authority in the US. These tablets were designed for daily use in the treatment of certain forms of myelofibrosis, polycythemia vera, and graft-versus-host disease (GVHD).

What Are the Emerging Segments in the Graft Versus Host Disease (GVHD) Treatment Market?
The graft versus host disease (GVHD) treatment market covered in this report is segmented -

1) By Product Type: Corticosteroids, Monoclonal Antibodies, Immunosuppressants, Others
2) By Disease Type: Acute GvHD, Prophylaxis GvHD, Chronic GvHD
3) By End User: Hospitals Pharmacies, Retail Pharmacies, Online Pharmacies

Subsegments:
1) By Corticosteroids: Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone, Betamethasone, Budesonide
2) By Monoclonal Antibodies: Anti-Inf Monoclonal Antibodies ( Infliximab, Adalimumab), Anti-il-2ra Monoclonal Antibodies ( Basiliximab), Anti-cd52 Monoclonal Antibodies (Alemtuzumab), Anti-il-6 Monoclonal Antibodies (Tocilizumab), Anti-Cd20 Monoclonal Antibodies (Rituximab)
3) By Immunosuppressants: Calcineurin Inhibitors (Cyclosporine, Tacrolimus), Methotrexate, Mycophenolate Mofetil, Azathioprine, Sirolimus (Rapamycin), Cyclophosphamide
4) By Others: Mesenchymal Stem Cells (Mscs), Jak Inhibitors ( Ruxolitinib), Extracorporeal Photopheresis (Ecp), Thalidomide, Antithymocyte Globulin (Atg), Colony-Stimulating Factors (Filgrastim)

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Who Are the Global Leaders in the Graft Versus Host Disease (GVHD) Treatment Market?
Major companies operating in the graft versus host disease (GVHD) treatment market are Pfizer Inc., Johnson & Johnson Services Inc., F. Hoffmann-La Roche Ltd., Merck & Co. Inc., Sanofi SA, Novartis AG, Bristol Myers Squibb, AstraZeneca, Abbott Laboratories, GlaxoSmithKline plc, Eli Lilly And Company, Novo Nordisk A/S, Takeda Pharmaceutical Company Limited, Gilead Sciences Inc., Merck KGaA, Teva Pharmaceutical Industries Ltd., Biogen Inc., Astellas Pharma Inc., Jazz Pharmaceuticals plc, Allergan plc, Incyte Corporation, Mallinckrodt Pharmaceuticals, Genzyme Corporation, Kiadis Pharma, Neovii Pharmaceuticals AG, ElsaLys Biotech SA, Mesoblast Ltd., Soligenix

Which are the Top Profitable Regional Markets for the Graft Versus Host Disease (GVHD) Treatment Industry?
North America was the largest region in the graft versus host disease (GVHD) treatment market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the graft versus host disease (GVHD) treatment market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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